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[Publications] Satoh,S., Ichikawa,A.et al.: "The Key Amino Acid Residue of Prostaglandin EP3 Receptor for Governing G Protein Association and Activation Steps." Biochem.Biophys.Res.Commun.255. 164-168 (1999)
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[Publications] Takahashi,S., Ichikawa,A.et al.: "Localization of a cyclopentenone prostaglandin to the endoplasmic reticulum and induction of BiP mRNA." Biochem.J.335. 35-42 (1998)
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[Publications] Katsuyama,M., Ichikawa,A.et al.: "Characterization of the gene for the mouse prostaglandin E receptor subtype EP2: tissue-specific initiation of transcription in the macrophage and the uterus." Biochem.J.330. 1115-1121 (1998)
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[Publications] Segi,E., Ushikubi,F.et al.: "Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice." Biochem.Biophys.Res.Commun.246. 7-12 (1998)
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[Publications] Suda,M., Ushikubi,F.et al.: "Prostaglandin E_2 (PGE_2) autoamplifies its production through EP1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells." Calcif.Tissue Int.62. 327-331 (1998)
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[Publications] Ushikubi,F.et al.: "Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3." Nature. 395. 281-284 (1998)
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[Publications] Ito,K., Haga,T.et al.: "Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 and 5." Eur.J.Biochem.(in press). 259. (1999)
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[Publications] Haga,K., Haga,T.et al.: "GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin." Eur.J.Biochem.255. 363-368 (1998)
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[Publications] Tsuga,H., Haga,T.et al.: "Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes: Role of third intracellular m2 loop and G protein-coupled receptor kinase 2." J.Biol.Chem.273. 5323-5330 (1998)
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[Publications] Adachi,K., Satoh,M.et al.: "Inhibition of NMDA receptors and nitric oxide synthase reduces ischemic injury of the retina." Eur.J.Pharmacol.350. 53-57 (1998)
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[Publications] Seki,T., Satoh,M.et al.: "Bremazocine recognizes the difference in four amino acid residues to discriminate between a nociceptin receptor and opioid receptors." Jpn.J.Pharmacol.77. 301-306 (1998)
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[Publications] Seki,T., Satoh,M.et al.: "DAMGO recognizes four residues in the third extracellular loop to discriminate between μ-and κ-opioid receptors." Eur.J.Pharmacol.350. 301-310 (1998)
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[Publications] Miyazaki,T., Fujii,H.et al.: "Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway." Genes & Development. 12. 770-775 (1998)
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[Publications] Fujii,H.et al.: "Functional dissection of the cytoplasmic subregions of the IL-2 receptor βc chain in primary lymphocyte populations." EMBO Journal. 17・22. 6551-6557 (1998)
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[Publications] Maeda,N., Kadomatsu,K.et al.: "A receptor-like tyrosine phosphataseζ (PTRζ/RPTPβ) binds midkine: involvement of arginine 78 of midkine in the high affinity binding to PTPζ" J.Biol.Chem.(in press). (1999)
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[Publications] Fan,Q.-W., Kadomatsu,K.et al.: "Expression of basigin, a member of the immunoglobulin superfamily, in the central nervous system." Neurosci.Res.30. 53-63 (1998)
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[Publications] Yokota,C., Kadomatsu,K.et al.: "Midkine counteracts the activin signal in mesoderm induction and promotes neural formation." J.Biochem.123. 339-346 (1998)
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[Publications] Illes,Z., Tabira,T.et al.: "Selective loss of invariant Vα24+ T-cells in the peripheral blood of MS patients." Neuroimmunology. 6. 50-51 (1998)
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[Publications] Tanahashi,H.and Tabira,T.: "Cloning of the cDNA encoding rat presenilin-2." Biochim.Biophys.Acta.1396. 259-262 (1998)
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[Publications] Inoue,H., Tanabe,T.et al.: "Glucocorticoid-Mediated Suppression of the Promoter Activity of the Cyclooxygenase-2 Gene Is Modulated by Expression of Its Receptor in Vascular Endothelial Cells." Biochem.Biophys.Res.Commun.254. 292-298 (1999)
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[Publications] Subbaramaiah,K., Tanabe,T.et al.: "Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorobol Ester-treated Human Mammary Epithelial Cells." J.Biol.Chem.273. 21875-21882 (1998)
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[Publications] Takahashi,S., Tanabe,T.et al.: "Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats." Am.J.Physiol.275. G1137-G1145 (1998)
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[Publications] Uehara,T., Nomura,Y.et al.: "Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells." J.Neurochem.72 (1). 196-205 (1999)
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[Publications] Araya,R., Nomura,Y.et al.: "Hypoxia induces apoptosis human neuroblastoma SK-N-MC cells caspase activation accompanying cytochrome C release from mitochondria." FEBS Lett.439. 168-172 (1998)
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[Publications] Sanchez,J.A., Inagaki,N.et al.: "Modelation of reconstituted ATP-sensitive K+ channels by GTP-binding proteins." J.Physiol.507. 315-324 (1998)
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[Publications] Nagao,K., Sakamoto,K.et al.: "Characterization of mRNA expression of prostaglandin F2α receptor regulatory protein in the pseudo-pregnant rat ovary." J.Reprod.Fertil.(submitted).
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[Publications] Hida,A., Seyama,Y.et al.: "Sexual differences in branched chain amino acid metabolism into fatty acids and cholesterol in Harderian gland of golden hamster." J.Biochem.124. 648-653 (1998)
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[Publications] Igarashi,T., Izumi,T.et al.: "Characterization of the leukotriene B4 receptor in porcine leukocytes. Separation and reconstitution with heterotrimeric GTP-binding proteins." Eur.J.Biochem.259. 419-425 (1999)
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[Publications] Ishii,I., Izumi,T.et al.: "Agonist-induced sequestration, recycling and resensitization of platelet-activating factor receptor: role of cytoplasmic tail phosphorylation in each process." J.Biol.Chem.273・16. 9878-9885 (1998)
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[Publications] Hiraoka,Y., Muramatsu,I.et al.: "Binding and functional characterization of α_1-adrenoceptor subtypes in the rat prostate." Eur.J.Pharmacol.366. 119-126 (1999)
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[Publications] Muramatsu,I.et al.: "α_1-Adrenoceptor subtypes and two receptor systems in vascular tissues." Life Science. 62 (17/18). 1461-1465 (1998)
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[Publications] Sakai,T., Muramatsu,I.et al.: "Persistent release of noradrenaline caused by anticancer drug 4'-epidoxorubicin in rat tail artery in vitro" Eur.J.Pharmacol.356. 25-30 (1998)
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[Publications] Hayashi,T., Iguchi,A.et al.: "Physiological concentration of 17β-estradiol inhibits the effect of inducible nitric oxide synthase in macrophage cell line: J774 by receptor mediated system." J.Cardiovascular Pharmacol.31. 292-298 (1998)
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[Publications] Ramos,M.A., Iguchi,A.et al.: "Induction of macrophage VEGF in response to oxidized LDL and VEGF accumulation in human atherosclerotic lesions." Arteriosclerosis, Thrombosis, and Vascular Biology. 18. 1188-1196 (1998)
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[Publications] Mukai,T., Saji,H.et al.: "Pharmacokinetic models to evaluate radiolebeling reagents for protein radiopharmaceuticals." Nucl.Med.Biol.25 (1). 31-36 (1998)
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[Publications] Yamamura,N., Saji,H.et al.: "Evaluation of 〔1-^<11>C〕octanoate as a new radiopharmaceutical for assessing liver function using positron emission tomography." Nucl.Med.Biol.25 (4). 467-472 (1998)
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[Publications] Nagata,T., Shichida,Y.et al.: "The hydrogen bonding network of water molecules and the peptide backbone in the region connecting Asp83,Gly120 and Glu113 in bovine rhodopsin." Biochemistry. 37. 17216-17222 (1998)
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[Publications] Terakita,A., Shichida,Y.et al.: "Selective activation of G-protein subtypes by vertebrate and invertebraterhodopsins." FEBS Lett.439. 110-114 (1998)
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[Publications] Tsukamoto,Y., Miki,N.et al.: "Involvement of gicerin, a cell adhesion molecule, in development and regeneration of oviduct, and metastasis of oviductal adenocarcinomas." Exp.Cell.Res.(in press). (1999)
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[Publications] Taira,E., Miki,N.et al.: "Neurite promotion from ciliary ganglion neurons by gicerin." Neurochem.Int.32. 23-29 (1998)
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[Publications] Hashimoto,H., Baba,A.et al.: "Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor." Genomics (in press). (1999)
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[Publications] Yamamoto,K., Baba,A.et al.: "Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene." Gene. 211. 63-69 (1998)
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[Publications] Sano,H., Ebina,Y.et al.: "Insulin enhances macrophage scavenger receptor-mediated endocytic uptake of advanced glycation end products." J.Biol.Chem.273. 8630-8637 (1998)
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[Publications] Lauro,D., Ebina,Y.et al.: "Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue." Nature Genetics. 20. 294-298 (1998)
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[Publications] Eguchi,N., Ito,S.et al.: "Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice." Proc.Natl.Acad.Sci.U.S.A.96. 726-730 (1999)
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[Publications] Okuda-Ashitake,E., Ito S.et al.: "Nocistatin, a peptide that blocks nociceptin action in pain transmission." Nature. 392. 286-289 (1998)
