2000 Fiscal Year Final Research Report Summary
The research of the influence of mastication on general health from the view of brain function
| Project/Area Number |
09470473
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
矯正・小児・社会系歯学
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| Research Institution | KYUSHU UNIVERSITY |
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Principal Investigator |
NAKATA Minoru Kyushu Univ., Faculty of Dental Science, Professor, 歯学研究院, 教授 (40014013)
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| Co-Investigator(Kenkyū-buntansha) |
HAYASAKI Haruaki Kyushu Univ., Faculty of Dental Science, Research Associate, 大学院・歯学研究院, 助手 (60238095)
YAMASAKI Youichi Kyushu Univ., School of Dentlstry, Assistant Professor, 歯学部・附属病院, 講師 (30200645)
FUJISE Takako Kyushu Univ., School of Dentlstry, Research Associate, 歯学部・附属病院, 助手 (50284518)
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| Project Period (FY) |
1997 – 2000
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| Keywords | mastication / energy metabolism / satiety center / growth ＆ development / braln histamine / brain function / mandibular movement / occlusion |
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| Research Abstract |
One of the main goals of dentistry is to achieve lifelong health of the masticatory function. Until very recently, however, the influence and significance of mastication on the global health of the human body have remained uncertain. The purpose of this study is to clarify the relationship between mastication and general health.
In the basic study, it was indicated that brain histamine function activated by mastication began earlier in the mesencephalic trigeminal nucleus and later in the ventromedial hypothalamic nucleus, the satiety center, due to a signal originating from the oral proprioceptors and initiated by chewing. And it was suggested the difference of oral proprioceptive sensation originated from food consistency and its signal procession in the hypothalamus caused the changes in energy balance that affects adiposity.
In the clinical study, the changes of chewing movement in the process of mastication of jelly with different texture were compared between children and adults. The new method was developed for easy visualization and diagnosis of mandibular movement measured by an opto-electonic movement analysis system. The measurement system that combined a tracking system for mandibular movements with a three-dimensioned digitizer for tooth shape was developed to record occlusal contacts during mandibular movement. Incisal and condylar paths during habitual mouth opening movement of children with anterior reverse bite in the primary dentition compared to those of children with normal dentition. These findings indicate that mastication is of great importance not only for the intake of food but also for the systemic and physical functions.
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[Publications] Fujise, T., Yoshimatsu, H., Kurokawa, M., Oohara, A., Kang, M., Nakata, M.and Sakata, T.: "Satiation and masticatory function modulated by brain histamine in rats"P.S.E.B.M.(Proceedings of the Society for Experimental Biology and Medicine). 217. 228-234 (1998)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Hayasaki, H., Nakata, S., Nishijima, N., Okamoto, A., Minematsu, K., Yamasaki, Y.& Nakata, M.: "CMDME (curved mesh diagram of mandibular excursion) method for visualization and diagnosis of mandibular movement"Journal of Oral Rehabilitation. 25. 672-676 (1998)
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「研究成果報告書概要(欧文)」より
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[Publications] Hayasaki, H., Nakata, S., Nishijima, N., Okamoto, A., Minematsu, K., Yamasaki, Y.& Nakata, M.: "A calculation method for the range of occluding phase at the lower incisal point during chewing movements using the curved mesh diagram of mandibular excursion (CMDME)"Journal of Oral Rehabilitation. 26. 236-242 (1999)
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「研究成果報告書概要(欧文)」より
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[Publications] Okamoto, A., Hayasaki, H., Nishijima, N., Iwase, Y., Yamasaki, Y.and Nakata, M.: "Occlusal contacts during lateral excursions in children with primary dentition"J.Dent.Res.. 79(11). 1890-1895 (2000)
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「研究成果報告書概要(欧文)」より
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[Publications] Nishijima, N., Hayasaki, H., Okamoto, A., Nakata, S., Yamasaki, Y.and Nakata, M.: "Difference in tracks between habitual open and close mandibular movements at the condyle in children"Journal of Oral Rehabilitation. 27(11). 999-1003 (2000)
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「研究成果報告書概要(欧文)」より
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