1999 Fiscal Year Final Research Report Summary
Establishment of Fundamental Technique of Electrode Surface Modification for Development on Molecularly Imprinted Sensor
| Project/Area Number |
09555265
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 展開研究 |
|---|
| Research Field |
工業分析化学
|
|---|
| Research Institution | KYUSHU UNIVERSITY |
|---|
Principal Investigator |
TAKAGI Makoto Grad. Sch. of Eng., Kyushu University, Professor, 大学院・工学研究科, 教授 (90037739)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAZAKI Masato Kumamoto Inst. of Tech., Fac. of Eng., Kyushu University, Associate Professor, 工学部, 助教授 (40112304)
NAKAMURA Shigeru Grad. Sch. of Eng., Kyushu University, Assistant Professor, 大学院・工学研究科, 助手 (00264078)
NAKANO Koji Grad. Sch. of Eng., Kyushu University, Associate Professor, 大学院・工学研究科, 助教授 (10180324)
|
|---|
| Project Period (FY) |
1997 – 1999
|
| Keywords | molecular imprinting / sensor / gold electrode / molecular recognition / polymer membrane |
|---|
| Research Abstract |
In recent years, sensor for selective detection of target molecular is developed. We have developed a new method of molecular imprinting, and have been trying to apply the method to sensor.
We started with a basic investigation of the structure of molecularly imprinted resin surface. The broadening of pKa was observed from proton titration of the resin. This results suggests the strong interaction between the functional groups and it is evidence that the carboxyl groups exist two dimensionally.
Formation of Self-assembled monolayer from alkaneselenol and electrochemical characterization of the modified electrode were investigated. Alkaneselenol absorb to gold electrode more strongly than corresponding alkanethiol. It should be understood from the fact that selenium is a softer ligand than sulfur and has high affinity to class B metal such as gold and silver.
We tried an application to the membrane electrode-type ion sensor as a method for evaluation of imprinting effect. Molecular imprinting membrane was prepared by the polymerization after permeation of the salt of functional monomer and organic cation into the membrane. This ion sensing membrane effectively responded to the template ion, but it was not perfect Nernstian response.
|
