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1999 Fiscal Year Final Research Report Summary

Treatment of dentin hypersensitivity by calcium phosphate precipitation method.

Research Project

Project/Area Number 09557152
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Conservative dentistry
Research InstitutionOsaka University

Principal Investigator

EBISU Shigeyuki  Faculty of Dentistry, Osaka University, Professor, 歯学部, 教授 (50116000)

Co-Investigator(Kenkyū-buntansha) SUGE Toshiyuki  School of Dentistry, Tokushima University, Research Associate, 歯学部, 助手 (60243713)
ISHIKAWA Kunio  Dental School, Okayama University, Assistant professor, 歯学部, 助教授 (90202952)
IMAZATO Satoshi  Faculty of Dentistry, Osaka University, Assistant professor, 歯学部, 助教授 (80243244)
Project Period (FY) 1997 – 1999
KeywordsDentin hypersensitivity / Calcium phosphate / Apatite / Dentinal tubules / Beagle dog / Scanning electron microscopy / Plaque control
Research Abstract

We have proposed calcium phosphate precipitation (CPP) method which occluded dentinal tubules with apatitic mineral for the treatment of dentin hypersensitivity. In this study, we aimed to evaluate occluding ability of CPP method in vivo using vital teeth of beagle dogs. Class V cavities were prepared in cervical of molars and canines in beagle dogs. Class V cavities were prepared in cervical of molars and canines in beagle dogs, then the teeth were etched with 50% citric acid for 2 min to open dentinal tubules. CPP solution (1M CaHPOィイD24ィエD2・2HィイD22ィエD2O, 2M HィイD23ィエD2POィイD24ィエD2) and post-treatment solution (1M NaHCOィイD23ィエD2, 0.3M NaF) were applied to the teeth with cotton swab. The teeth were divided into two groups, (1) plaque control made by brushing, and (2) nonplaque control group. Dentin biopsy was performed to obtain dentin specimens using cylindrical diamond point immediately after treatment and seven days after treatment with CPP method. The surface and fractured surface of the specimens were observed by scanning electron microscopy. We found that dentinal tubules were occluded homogeneously and completely with apatitic precipitate up to 5 μm from the dentin surface when CPP treatment was made. In non-plaque control group, the dentinal tubules became open seven days after CPP treatment. In contrast, most of the dentinal tubules were still occluded with the precipitate in plaque control group. We concluded that CPP method is useful for the treatment of dentin hypersensitivity when proper plaque control was made. In the other words, plaque control plays a key role for the duration of the dentin hypersensitivity treatment with CPP method.

  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] T. Suge et al: "Evaluation of post-treatment solution for clinical use with the calcium phosphate precipitation method"Journal of Dentistry. 27・7. 487-496 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] A. Kawasaki et al.: "Effects of plaque control on the patency and occlusion of dentine tubules in situ"Journal of Oral Rehabilitation. 27(In press). (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T. Suge et al: "Comparison of dentinal tubules occlusion - CPP, Resin and Potassium oxalate"Journal of Dental Research. 77・special Issue. 651 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] A. Kawasaki et al.: "In vivo evaluation of plaque control on dentin hypersensitivity"Journal of Dental Research. 77・special Issue. 671 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T. Suge et al: "Evaluation of post-treatment solutions for clinical use with the calcium phosphate precipitation method"Journal of Dentistry. 27 (7). 487-496 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] A. Kawasaki et al: "Effects of plaque control on the patency and occlusion of dentine tubules in situ"Journal of Oral Rehabilitation. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Suge et al: "Comparison of dentinal tubules occlusion-CPP, Resin and potassium oxalate"Journal of Dental Research. 77 (Special issue). 651 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] A. Kawasaki et al: "In vivo evaluation of plaque control on dentin hypersensitivity"Journal of Dental Research. 77 (Special issue). 671 (1998)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2001-10-23   Modified: 2017-10-11  

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