2000 Fiscal Year Final Research Report Summary
EPIDEMIOLOGICAL STUDY ON EFFICACY OF SCREENING PROGRAMME FOR COLORECTAL CANCER
| Project/Area Number |
09670384
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | SHINSHU UNIVERSITY |
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Principal Investigator |
NAKAMA Hidenori SCHOOL OF MEDICINE, SHINSHU UNIVERSITY ASSOCIATE PROFESSOR, 医学部, 助教授 (50207859)
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| Project Period (FY) |
1997 – 2000
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| Keywords | Colorectal cancer / Colorectal cancer screening / Epidemiological evaluation / Efficacy / Immunochemical faecal occult blood test / Time trend assessment / Case-control study / Mortality |
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| Research Abstract |
A population-based screening program using faecal occult blood test has been conducted since 1982 in the small village of Asahi, Nagano, Japan (index area). The present study analyses the efficacy of the above program to reduce mortality of colorectal cancer. When the screening program started in 1982, the index area had a population of 4,248 (2,120 male ; 2,128 female) including 2,177 (1,030 male ; 1,147 female) aged 40+ years. Annual screening examination have been conducted in the population aged 40+ years. All participants were screened by faecal occult blood test. Subjects who were positive underwent further examination by total colonoscopy. The SMR and SIR were used to assess the efficacy of screening. Changes in mortality and incidence of the index area were compared with nationwide data for the period before screening and for the screening period. The SMR and SIR in Asahi were higher in the period before screening than in those during screening. These results confirm that the screening program conducted in the index area was effective as a community measure in reducing mortality from colorectal cancer.
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Research Products
(16 results)
