1998 Fiscal Year Final Research Report Summary
Hypersensitivity to cold exposure and emotional stimuli in hand-arm vibration syndrome patients
| Project/Area Number |
09670392
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Yamaguchi University |
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Principal Investigator |
HARADA Noriaki Yamaguchi University School of Medicine, Professor, 医学部, 教授 (70116747)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMOTO Minoru Yamaguchi University, School of Medicine, Assistant Professor, 医学部, 講師 (20227961)
IWAMOTO Mieko Yamaguchi University, School of Medicine, Assistant Professor, 医学部, 講師 (80034932)
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| Project Period (FY) |
1997 – 1998
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| Keywords | hand-arm vibration syndrome / cold exposure / emotional stimuli / autonomic nervous system / adrenal medulla / catecholamine / PF4 / betaTG |
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| Research Abstract |
Influences of season and food intake on the cold exposure test of one hand for the hand-arm vibration syndrome were investigated. Finger skin temperature in summer was higher than that in winter. Especially in winter, the finger skin temperature after food intake was higher than that in fasting condition. Heart rate variation during the cold immersion after food intake was larger than that in fasting condition.
When comparing to immersing a hand in cold water at 15ﾟC for 3 minutes, method using cold water at 10ﾟC for 10 minutes indicated larger differences of finger skin temperature between hand-arm vibration syndrome patients and healthy controls with statistical significance.
Evaluations of heart rate variation and catecholamines, PF4, and beta TG indicated that hand-arm syndrome patients had larger responsibility of the sympathetic nervous system and the adrenal medulla to emotional stimuli as well as cold exposure.
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