1998 Fiscal Year Final Research Report Summary
Efficacy of dietary guidance to reduce high blood cholesterol in city dwellers : A randomized controlled trial
| Project/Area Number |
09670407
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka City University |
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Principal Investigator |
DATE Chigusa Osaka City University, Medical School, Associate Professor, 医学部, 助教授 (60047389)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Takashi Osaka City University, Medical School, Lecturer, 医学部, 講師 (30227144)
TANAKA Heizo Tokyo Medical and Dental University, Medical Research Institute, Professor, 難治疾患研究所, 教授 (70047215)
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| Project Period (FY) |
1997 – 1998
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| Keywords | randomized controlled trial / dietary guidance / serum total cholesterol / LDL cholesterol / dietary fat / dietary cholesterol |
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| Research Abstract |
Purpose
To clarify the lowering effect of serum total cholesterol(TCH) through dietary guidance by randomized controlled trial(RTC) conducted with city dwellers.
Method
It was conducted with citizens in District A in Osaka City and District A-I in Osaka Prefecture. People who were encouraged by telephone or letter to participate in RTC are follows : those aged between 40 and 69, whose TCH and HDL-CH measured at the time of health check-ups 6 months prior to RCT were between 230 and 279 mg/dl, and below 90 mg/dl, respectively. The candidates had the nature of RCT and the dietary guidance method explained to them, and gave informed consent by document.
The first baseline examination was implemented in District A in May, 1997 and in District A-I in June, 1998. The number of the examinees was 92, and after eliminating those whose TCH was below 230 mg/dl, the qualified ones numbered 56 in District A and 19 in DistrictA-I, totaling 75. They were divided into two groups by randomized allocation and designated as a intervention group(IG), and a control group(CG). Regarding each one of the former group, three by-monthly dietary guidance sessions took place with a special focus on fat intake. Six months after the first examination, the second one was conducted with both groups.
Results
The IG and the CG numbered 38 and 37, respectively, It was found that there was no difference in age and the mean measurements of TCH and BMI as found in the first examination.
As far as the IG was concerned, TCH went down to 231.9 mg/dl in the second examination from 256.5 mg/dl showed in the first. The CG showed 252.7 mg/dl in the second examination, down from 256.6 mg/dl in the first. The net reduction of TCH through dietary guidance proved to be 20.7 mg/dl.
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Research Products
(4 results)
