| Research Abstract |
Human persistently infectious viruses (HIV, HTLV, HCV, HBV and so on) are broadly epidemic all over the world. We attempted to establish a therapeutic model of persistently infectious virus using HCV and hepatic cancer. We first analyzed to identify the toxic element of HCV, and then, established the methods of reactivation of inactive T cell by using B7. Following these experiment, we established the therapeutic methods of activation of the apoptotic signal of cancer cells. In this research, we identified toxic element of the virus and novel epitope of hepatic cancer, established T cell line recognizing hepatic cancer and therapeutic vector against cancer.
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