1999 Fiscal Year Final Research Report Summary
Importance of fiber type characteristics of the skeletal muscle as a determining factor for the degree of obesity
| Project/Area Number |
09680110
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
体育学
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
MATOBA Hideki The University of Tokushima, Faculty of Integrated Arts and Sciences, Professor, 総合科学部, 教授 (20035166)
|
|---|
| Project Period (FY) |
1997 – 1999
|
| Keywords | obesity / muscle fiber type / skeletal muscle |
|---|
| Research Abstract |
Three experiments were conducted in order to elucidate the role of fiber type characteristics of the skeletal muscle in determining the degree of obesity. In the first experiment, fiber type characteristics of the skeletal muscles of Zucker obese rat , the model animal with genetic predisposition for obesity, were compared with those of non-obese control rat. The results indicated that oxidative capacity of the skeletal muscle as a whole was lower in the Zucker rat, which was attributable to lower skeletal muscle mass. The second experiment examined the relationship between metabolic capacity of the skeletal muscle and abdominal fat deposition in the rat fed either high-fat diet or normal diet. In the rats fed normal diet, significant negative relationship existed between oxidative capacity of the skeletal muscle and abdominal fat weight. High-fat diet induced obesity despite the augmentation of the oxidative capacity of the skeletal muscle. The third experiment examined whether or not physical training employing voluntary wheel running, which is known to increase the oxidative capacity of the skeletal muscle and to suppress the deposition of abdominal fat, induced the change in resting metabolism or respiratory exchange ratio R. The results showed that the training induced no significant change in resting metabolic rate and R, despite a significant increase in MDH activity and a significant decrease in abdominal fat weight.
|
Research Products
(8 results)
