1998 Fiscal Year Annual Research Report

マンモグラフィーの計算機支援診断システムの開発とその実用化のための基礎研究

Research Project

Project/Area Number	10044136
Research Category	Grant-in-Aid for international Scientific Research
Section	Joint Research .
Research Institution	Tokyo University of Agriculture and Technology
Principal Investigator	小畑秀文東京農工大学, 大学院・生物システム応用科学研究科, 教授 (80013720)
Co-Investigator(Kenkyū-buntansha)	NISHIKAWA Ro シカゴ大学, 医学部, 助手 DOI Kunio シカゴ大学, 医学部, 教授萩原義裕東京農工大学, 工学部, 助手村上康二国立がんセンター, 東病院放射線部, 医員(研究職) 縄野繁国立がんセンター, 東病院放射線部, 医長(研究職)
Keywords	マンモグラフィー / 計算機支援診断 / CAD / 乳房X線像 / スクリーニング / 乳がん / 腫癌影 / 微小石灰化像
Research Abstract	本年度は東京農工大学と米国シカゴ大学とが開発した乳がん診断支援システム(CAD)の性能評価をそれぞれの立場から行い、相手側システムに対しての批評や助言を通して、システムの改良点を明確化することに主眼をおいた。平成10年6月にはシカゴ大学のグループが来日し、東京農工大学および国立がんセンター東病院にて意見交換の場を持った。東京農工大学においては、我々が開発した診断支援システムについて、主として工学サイドからアルゴリズムのさらなる高度化のために必要な具体策について、意見の交換を行った。また、国立がんセンター東病院においては、我々のシステムの臨床評価実験の結果や、具体的症例に基づいた医学および工学的立場からの意見交換を行った。平成10年11月〜12月には、日本側研究グループが米国シカゴ大学を訪問し、先方の開発したシステムについて議論を交わすと共に、診断支援システムを利用した場合と利用しない場合の診断率の変化を体験し、CADシステムの効果を実際に体験する機会を得た。

Research Products
(19 results)

All Other

All Publications (19 results)

[Publications] 小畑秀文、村上正行: "アイリスフィルタとその特性解析" 計測自動制御学会論文誌. 34・4. 326-332 (1998)
[Publications] S.Hashimoto,H.Kobatake,H.Takeo and S.Nawano: "Automated Tumor Detection System for Full-Digital Mammography Using Bilateral Comparison in Feature Space" Proc.of CAR'98. 207-212 (1998)
[Publications] F.Iseki,H.Kobatake,H.Omatsuand R.Kakinuma: "Extraction of 3D Tree Structure of Blood Vessels in Lung Area from Chest CT Images" Proc.of CAR'98. 45-50 (1998)
[Publications] H.Kitaoka,R.Takaki,K.Itoh,F.Iseki,H.Kobatake,H.Ohmatsu,N.Moriyama and K.Eguchi: "Spape Analysis of Pulmonary Nodules in 3D-CT Images withh a New Method of Curvature Estimation" Proc.of CAR'98. 51-56 (1998)
[Publications] H.Kobatake,H.Takeo and S.Nawano: "Tumor Deteotion System for Full-Digital Mammography,N.Karssemeijer et al.Ed." Digital Mammography. 87-94 (1998)
[Publications] H.Kobatake,H.Takeo and S.Nawano: "Microcalcification Detection System for Full-Digital Mammography,N.Karssemeijer et al.Ed." Digital Mammography. 201-204 (1998)
[Publications] 吉永幸靖、小畑秀文: "濃度勾配ベクトルを用いたコントラストや幅に影響されない線領域の検出法" 電子情報通信学会論文誌. J81-D・II. 2547-2555 (1998)
[Publications] 萩原義裕、小畑秀文,志田寿夫: "CT画像を用いたじん肺粒状影の抽出とじん肺症自動分類の試み" Medical Imaging Technology. 16・5. 578-584 (1998)
[Publications] Yukiyasu Yoshinaga and Hidefumi Kobatake: "Robust extraction of curvilinear convex regions with weak contrast using a gradient vector distribution model" Proc.of Int.Symp.on Noise Reduction for Imaging and Communication Systems. 157-162 (1998)
[Publications] Doi K,GigerML,Nishikawa RM,Schmidt RA: "Computer vision and artifical intelligence in mammography." Diagnostik und Therapie des Mammakarzinoms:State of the Art.11-16 (1998)
[Publications] Zhang W,Yoshida H,Nishikawa RM,Doi K: "Optimally weighted wavelet transform based on supervised training for detection of microcalcifications in digital mammograms" Med Phys. 25. 949-956 (1998)
[Publications] Huo Z,Giger ML,Vybomy CJ,WolvertonDE,SchmidtRA,Doi K: "Automated computerized classification of malignant and benign mass lesions on digitized mammograms" Acad Radiol. 5. 155-168 (1998)
[Publications] Nagel RH,Nishikawa RM,Papaioannou J,Doi K: "Analysis of methods for reducing false positives in the automated detection of clustered microcalcifications in mammograms" Med Phys. 25. 1502-1506 (1998)
[Publications] Giger ML,Huo Z,Wolverton DE,Vybomy CJ,Moran C,SchmidtRA,ALHallaqH,Nishikawa RM,Doi K: "Computer-aided diagnosis of digital mammographic and ultrasound images of breast mass lesions" Digital Mammography 1998. 143-148 (1998)
[Publications] Jiang Y,Nishikawa RM,Schmidt RA,Metz CE,Giger ML,Doi K: "Benefits of computer-aided diagnosis (CAD) in mammographic diagnosis of malignant and benign clustered microcalcifications" Digital Mammography 1998. 215-220 (1998)
[Publications] Nishikawa RM,Giger ML,Wolverton DE,Schmidt RA,Comstock CE,Papaioannou J.Collins SA,Doi K: "Prosoective testing of a clinical mammography workstation for CAD:Analysis of the first 10,000 cases" Digital Mammography 1998. 401-406 (1998)
[Publications] Huo Z,Giger ML,Olopade FL,Wolverton DE,Cummings S,Zhong W,Doi K: "Computerized analysis of digitized mammograms of women with low breast cancer risk and of BRCA1/BRCA2 gene-mutation carriers" Digital Mammography 1998. 419-422 (1998)
[Publications] Anastasio MA,Yoshida H,Nagel R,Nishikawa RM,Doi K: "A genetic algoritha-based method for optimizing the performance of a computer-aided diagnosis scheme for detection of clustered microcalcifications in mammograms" Med Phys. 25. 1613-1620 (1998)
[Publications] Jiang Y,Nishikawa RM,Schmidt RA,Metz CE,Giger MI,Doi K: "Improving breast cancer diagnosis with computer-aided diagnosis" Acad Radiol. 6. 22-33 (1999)

1998 Fiscal Year Annual Research Report

マンモグラフィーの計算機支援診断システムの開発とその実用化のための基礎研究

Principal Investigator

小畑 秀文 東京農工大学, 大学院・生物システム応用科学研究科, 教授 (80013720)

Research Products

[Publications] 小畑秀文、村上正行: "アイリスフィルタとその特性解析" 計測自動制御学会論文誌. 34・4. 326-332 (1998)

[Publications] S.Hashimoto,H.Kobatake,H.Takeo and S.Nawano: "Automated Tumor Detection System for Full-Digital Mammography Using Bilateral Comparison in Feature Space" Proc.of CAR'98. 207-212 (1998)

[Publications] F.Iseki,H.Kobatake,H.Omatsuand R.Kakinuma: "Extraction of 3D Tree Structure of Blood Vessels in Lung Area from Chest CT Images" Proc.of CAR'98. 45-50 (1998)

[Publications] H.Kitaoka,R.Takaki,K.Itoh,F.Iseki,H.Kobatake,H.Ohmatsu,N.Moriyama and K.Eguchi: "Spape Analysis of Pulmonary Nodules in 3D-CT Images withh a New Method of Curvature Estimation" Proc.of CAR'98. 51-56 (1998)

[Publications] H.Kobatake,H.Takeo and S.Nawano: "Tumor Deteotion System for Full-Digital Mammography,N.Karssemeijer et al.Ed." Digital Mammography. 87-94 (1998)

[Publications] H.Kobatake,H.Takeo and S.Nawano: "Microcalcification Detection System for Full-Digital Mammography,N.Karssemeijer et al.Ed." Digital Mammography. 201-204 (1998)

[Publications] 吉永幸靖、小畑秀文: "濃度勾配ベクトルを用いたコントラストや幅に影響されない線領域の検出法" 電子情報通信学会論文誌. J81-D・II. 2547-2555 (1998)

[Publications] 萩原義裕、小畑秀文,志田寿夫: "CT画像を用いたじん肺粒状影の抽出とじん肺症自動分類の試み" Medical Imaging Technology. 16・5. 578-584 (1998)

[Publications] Yukiyasu Yoshinaga and Hidefumi Kobatake: "Robust extraction of curvilinear convex regions with weak contrast using a gradient vector distribution model" Proc.of Int.Symp.on Noise Reduction for Imaging and Communication Systems. 157-162 (1998)

[Publications] Doi K,GigerML,Nishikawa RM,Schmidt RA: "Computer vision and artifical intelligence in mammography." Diagnostik und Therapie des Mammakarzinoms:State of the Art.11-16 (1998)

[Publications] Zhang W,Yoshida H,Nishikawa RM,Doi K: "Optimally weighted wavelet transform based on supervised training for detection of microcalcifications in digital mammograms" Med Phys. 25. 949-956 (1998)

[Publications] Huo Z,Giger ML,Vybomy CJ,WolvertonDE,SchmidtRA,Doi K: "Automated computerized classification of malignant and benign mass lesions on digitized mammograms" Acad Radiol. 5. 155-168 (1998)

[Publications] Nagel RH,Nishikawa RM,Papaioannou J,Doi K: "Analysis of methods for reducing false positives in the automated detection of clustered microcalcifications in mammograms" Med Phys. 25. 1502-1506 (1998)

[Publications] Giger ML,Huo Z,Wolverton DE,Vybomy CJ,Moran C,SchmidtRA,ALHallaqH,Nishikawa RM,Doi K: "Computer-aided diagnosis of digital mammographic and ultrasound images of breast mass lesions" Digital Mammography 1998. 143-148 (1998)

[Publications] Jiang Y,Nishikawa RM,Schmidt RA,Metz CE,Giger ML,Doi K: "Benefits of computer-aided diagnosis (CAD) in mammographic diagnosis of malignant and benign clustered microcalcifications" Digital Mammography 1998. 215-220 (1998)

[Publications] Nishikawa RM,Giger ML,Wolverton DE,Schmidt RA,Comstock CE,Papaioannou J.Collins SA,Doi K: "Prosoective testing of a clinical mammography workstation for CAD:Analysis of the first 10,000 cases" Digital Mammography 1998. 401-406 (1998)

[Publications] Huo Z,Giger ML,Olopade FL,Wolverton DE,Cummings S,Zhong W,Doi K: "Computerized analysis of digitized mammograms of women with low breast cancer risk and of BRCA1/BRCA2 gene-mutation carriers" Digital Mammography 1998. 419-422 (1998)

[Publications] Anastasio MA,Yoshida H,Nagel R,Nishikawa RM,Doi K: "A genetic algoritha-based method for optimizing the performance of a computer-aided diagnosis scheme for detection of clustered microcalcifications in mammograms" Med Phys. 25. 1613-1620 (1998)

[Publications] Jiang Y,Nishikawa RM,Schmidt RA,Metz CE,Giger MI,Doi K: "Improving breast cancer diagnosis with computer-aided diagnosis" Acad Radiol. 6. 22-33 (1999)

小畑秀文東京農工大学, 大学院・生物システム応用科学研究科, 教授 (80013720)