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[Publications] Matsui T. et al.: "K-Ras mediates cytokine-induced formation of adherens junctions during liver development"EMBO J.. 21. 1021-1030 (2002)
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[Publications] Takeuchi M. et al.: "Cultivation of AGM-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances homing to the bone marrow"Blood. 99. 1190-1196 (2002)
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[Publications] Kinoshita T. et al.: "Oncostatin M suppresses generation of progenitors in fetal liver by inhibiting the hepatic microenvironment"Experimental Hematology. 29. 1091-1097 (2001)
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[Publications] Tanaka, M. et al.: "Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes and regulates cell cycling as a downstream molecule of TPO signaling"J. Biol. Chem.. 276. 15082-15089 (2001)
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[Publications] Kirito, K. et al.: "Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation"Blood. 99. 102-110 (2002)
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[Publications] Kirito, K. et al.: "A Functional role of Stat3 in in vivo megakaryopoiesis"Blood. (in press). (2002)
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[Publications] Kirito, K. et al.: "TPO regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol-3-kinase activation pathways"J. Biol. Chem.. (in press). (2002)
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[Publications] Fukurnoto, T. et al.: "The Fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells"J. Biol. Chem.. 276. 38441-38448 (2001)
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[Publications] Kawasaki, A. et al.: "Down-regulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells"J. Cell Biol.. 152. 275-287 (2001)
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[Publications] Nojima, J. et al.: "Anti-prothrombin antibodies combined with lupus anticoagulant activity is an essential risk factor for venous thrombolism in patients with systemic lupus erythrmatosus"Br. J. Haematol. 114. 647-654 (2001)
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[Publications] Ueda, S. et al.: "Critical roles of c-kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis : contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration"Blood. (in press). (2002)
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[Publications] Sonoyama, J. et al.: "Functional cooperation among Ras, STAT5, and PI3-K is required for full oncogenic activities of BCR/ABL in K562 cells"J. Biol. Chem.. (in press). (2002)
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[Publications] Mizuki, M. et al.: "Role of receptor tyrosine kinases in hematological malignancies"Res. Adv. Blood. (in press). (2002)
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[Publications] Takizawa, T. et al.: "Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3"Cytokine. 13. 272-279 (2001)
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[Publications] Nakashima, K. et al.: "BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis"Proc. Natl. Acad. Sci. USA. 98. 5868-5873 (2001)
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[Publications] Ochiai, W. et al.: "Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of stat3"Cytokine. 14. 264-271 (2001)
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[Publications] Takizawa, T. et al.: "DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain"Dev. Cell. 1. 749-758 (2001)
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[Publications] Nishinakanmra, R. et al.: "Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development"Development. 128. 3105-3115 (2001)
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[Publications] Wakioka, T. et al.: "Spred, a Sprouty-related suppressor of Ras signaling"Nature. 412. 647-651 (2001)
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[Publications] Shouda, T. et al.: "Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis"J. Clin. Invest.. 108. 1781-1788 (2001)
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[Publications] Hanada, T. et al.: "A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAI3/CIS family proteins through the SOCS-box"J. Biol. Chem.. 276. 40746-40754 (2001)
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[Publications] Sasaki, A. et al.: "Identification of a dominant negative form of Sproutys that potentiates FGF-but not EGF-induced ERK activation"J. Biol. Chem.. 276. 36804-36808 (2001)
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[Publications] Suzuki, A. et al.: "CIS3/SOCS3/SSI3 Plays a Negative Regulatory Role in STAT3 Activation and Intestinal Inflammation"J. Exp. Med.. 193. 471-482 (2001)
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[Publications] Kamizono, S. et al.: "The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2"J. Biol. Chem.. 276. 12530-12538 (2001)
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[Publications] Minehata, K. et al.: "Macrophage-colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region"Blood. (in press). (2002)