2000 Fiscal Year Final Research Report Summary
Investigation of Intelligent Network Topology by Mimicking the Fault-tolerant Network Structure of Metabolic Pathways
| Project/Area Number |
10555128
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
情報通信工学
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| Research Institution | Kyushu Institute of Technology |
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Principal Investigator |
OKAMOTO Masahiro Dept.of Biochemical Engineering & Science, Kyushu Institute of Technology, Associate Professor, 情報工学部, 助教授 (40211122)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAKAWA Takeshi Dept.of Control Science & Engineering, Kyushu Institute of Technology, Professor, 情報工学部, 教授 (00005547)
EGUCHI Yukihiro Mitsui Knowledge Industry, Head of Research Institute, 総合研究所, 所長
OIE Yuji Dept.of Computer & Electrical Engineering, Kyushu Institute of Technology, Professor, 情報工学部, 教授 (50167293)
MIZOGUCHI Yoshihiro Dept.of Control Science & Engineering, Kyushu Institute of Technology, Associate Professor, 情報工学部, 助教授 (80209783)
久原 哲 九州大学, 大学院・農学研究院, 教授 (00153320)
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| Project Period (FY) |
1998 – 2000
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| Keywords | network topology / development of functional device / fault-tolerant / metabolic pathway / traffic control of telecommunication / simulator capture |
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| Research Abstract |
In spite of taking the continuous perturbations, metabolic pathways can keep the homeostatic capability of biochemical information. They may be fault-tolerant against external perturbations and take multi-compensating structure. By mimicking these features as for the network topology of metabolic pathways, we can propose the intelligent fault-tolerant network topology of telecommunications. We have implemented an efficient, user-friendly "biosimulator" named BEST-KIT (Biochemical Engineering System analyzing Tool-KIT) for analyzing a large scaled nonlinear reaction network such as metabolic pathways. The BEST-KIT mainly consists of two kinds of modules, "MassAction" and "EnzymeKinetics". In this study, we have developed new module, "MassAction++", which can construct and analyze reaction scheme represented by both mass action law (mass balance) and approximated velocity functions of enzyme kinetics at steady state. All modules in BEST-KIT are developed in Java applet style, and can be carried out on the "any" platform machine through the web browser. The "MassAction++" was developed by Java applet style and can save data related on the constructed reaction scheme and time course data on the client disk space and can load it to the web browser.
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