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2000 Fiscal Year Final Research Report Summary

Development of advanced CAD system for mammography and its practical application

Research Project

Project/Area Number 10555136
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section展開研究
Research Field Measurement engineering
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

KOBATAKE Hidefumi  Tokyo University of Agriculture and Technology Graduate School of Bio-Applications and Systems Engineering Professor, 大学院・生物システム応用科学研究科, 教授 (80013720)

Co-Investigator(Kenkyū-buntansha) HAGIHARA Yoshihiro  Tokyo University of Agriculture and Technology Graduate School of Bio-Applications and Systems Engineering Research Associate, 大学院・生物システム応用科学研究科, 助手 (80293009)
SHIMIZU Akinobu  Tokyo University of Agriculture and Technology Graduate School of Bio-Applications and Systems Engineering Associate Professor, 大学院・生物システム応用科学研究科, 助教授 (80262880)
NAWANO Shigeru  National Cancer Center Department of Radiology Director, 放射線部, 医長
TAKEO Hideya  Fuji Photofilm Co.Ltd. Miyanodai Research and Development Center Researcher, 宮台技術開発センター, 研究員
Project Period (FY) 1998 – 2000
KeywordsComputer Aided Diagnosis / CAD / Mammography / breast cancer / microcalcifications / tumor
Research Abstract

The purpose of this research project is to develop an improved CAD system for mammography and to heighten the system performance. The main results are as follows.
[1]System robust to variations of imaging condition
The conventional CAD system has been installed is five medical institutions in Japan and its performance had been tested . Each medical institution has its own imaging conditions and the performance of the conventional system depends on them. We have developed new processing algorithm, which makes the CAD system insensitive to the variation of imaging conditions.
[2]Revised tumor detection method
Adaptive ring filter has been developed, which makes it possible to detect tumors with rough and irregular density distributions. The performance of the adaptive ring filter has been shown to be superior to that of the iris filter.
[3]Detection of tumors close to or attached to thoracic wall
Tumors close to or attached to thoracic wall tend to be missed by the conventional CAD system. The detection algorithm for them has been revised. That is, the candidates in the area near thoracic wall are recognized by the different algorithm developed by this project. The performance of the new system has become higher than that of the conventional system.
[4]Advanced microcalcification detection method
Coarse-calcification causes false microcalcifications. We have developed a new method for coarse-calcification detection, which can help decreasing false microcalcification clusters. Complicated background can cause false microcalcifications. We have also developed an algorithm to exclude them.
These methods described above have been installed in the new CAD system.

  • Research Products

    (25 results)

All Other

All Publications (25 results)

  • [Publications] Yukiyasu Yoshinaga and Hidefumi Kobatake: "The Line Detection Method with Robustness against Contract and Width Variation Applied in Gradient Vector Field"Systems and Computers in Japan. 31. (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 荻原義裕,小畑秀文 縄野繁,武尾英哉: "モルフォロジカルフィルタの改良による乳がん微小石灰化像検出システムの高度化"Medical Imaging Technology. 18. 795-804 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 委鬼軍,荻原義裕,清水昭伸 小畑秀文: "勾配ベクトルの点集中性フィルタの特性解析"電子情報通信学会論文誌. J84-D. (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小畑秀文: "マンモグラフィにおけるCADシステムの開発"DIGITAL MEKICINE. 1. 77-79 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H. Kobatake, Wei Jun Y. Yoshinaga Y. Hogihara, A. Shimizu: "Nonlinear Adaptive Couvergence Index Filters and Their applications"ICPR. 3. 526-529 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y. Hagihara, H. Kobatake S. Nawano, H. Takeo: "Accurate Detection of Microcalcifications on Mammograms by Improvenent of Morphological Processing"IWDM. (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H. Sakai, A. Shimizu, Y. Hagihara H. Kobatake, S. Nawano, H. Takeo: "Improved Detection Method of Tumor Candidates on Digital Mammograms"IWDM. (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Kobatake and M.Murakami: "Characteristics Analysis of the Iris Filter"Transaction of the Society of Instrument and Control Engineers. Vol.34, No.4. 326-332 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Hashimoto, H.Kobatake, H.Takeo and S.Nawano: "Automated Tumor Detection System for Full-Digital Mammography Using Bilateral Comparison in Feature Space"CAR'98. 207-212 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H.Kobatake, H.takeo and S.Nawano: "Tumor Detection System for Full-Digital Mammography"Digital Mammography. 87-94 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H.Kobatake, H.Takeo and S.Nawano: "Microcalcification Detection System for Full-Digital Mammography"Digital Mammography. 201-204 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y.Yoshinaga and H.Kobatake: "The Line Detection Method with Robustness against Contrast and Width Variation Applied in Gradient Vector Field, The Transactions of Institute of Electrics"Information and Communication Engineers. Vol.J81-D・II. 2547-2555 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yukiyasu Yoshinaga and Hidefumi Kobatake: "Robust extraction of curvilinear convex regions with weak contrast using a gradient vector distribution model"Int.Symp.on Noise Reduction for Imaging and Communication Systems. 157-162 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Nawano, K.Murakami, N.Moriyama, H.Kobatake, H.Takeo and K.Shimura: "Computer-Aided Diagnosis in Full Digital Mammography"Investigative Radiology. Vol.34, No.4. 310-316 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hidefumi Kobatake and Shigeru Hashimoto: "Convergence Index Filter for Vector Fields"IEEE Trans.on Image Processing. Vol.8, No.8. 1029-1038 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H.Kobatake, M.Murakami, H.Takeo and S.Nawano: "Computerized detection of malignant tumors on digital mammograms"IEEE Trans.on Medical Imaging. Vol.18, No.5. 369-378 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jun Wei, Yoshihiro Hagihara and Hidefumi Kobatake: "Detection of Rounded Opacities on Chest Radiographs Using Convergence Index Filter"Proc.of ICIAP, pp.757-761, Venice. (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yukiyasu Yoshinaga, Hidefumi Kobatake and Shigehiro Fukushima: "The detection and Feature Extraction Method of Curvilinear Convex Regions with Weak Contrast Using a Gradient Distribution Method"Proc.ICIP. Paper No.26PP1.7 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jun Wei, Yoshihiro Hagihara and Hidefumi Kobatake: "Detection of Cancerous Tumors on Chest X-ray Images Candidate Detection Filter and Its Application"Proc.of ICIP. Paper No.27AP4.2 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hidefumi KOBATAKE, WEI Jun, Yukiyasu Yoshinaga and Yoshihiro HAGIHARA: "Nonlinear Adaptive Filters Based on Gradient Vector Orientation"Proc.Of International Symposium on nonlinear Theory and Its Applications, Hawaii. 553-556 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M.Murakami, H.Kobatake, H.Takeo and S.Nawano: "Feature Extraction of Malignant Tumors on Mammograms"Medical Imaging Technology. Vol.17, No.6. 681-689 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Hashimoto, H.Kobatake, H.Takeo and S.Nawano: "Reduction of False Positives Using Qualitative Feature Comparison of Bilateral Mammograms"The Transactions of Institute of Electrics, Information and Communication Engineers, D-II. Vol.J83-D-II, No.1. 415-418 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y.Hagihara and H.Kobatake: "A Histogram-Based Morphological Filter to Suppress Artifacts"The Transactions of Institute of Electrics, Information and Communication Engineers. Vol.J82-D・II, No.1. 101-108 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y.Hagihara and H.Kobatake: "A Morphological Filter with Region Expansion to Extract Minute Convex Regions and Its Application to Medical Image Processing"The Transactions of Institute of Electrics, Information and Communication Engineers. Vol.J83-D-II, No.1. 109-117 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] J.Wei, Y.Hagihara and H.Kobatake: "Convergence Index Filter for Detection of Lung Nodule Candidates"The Transactions of Institute of Electrics, Information and Communication Engineers, Vol.J83-D・II, No.1. 118-125 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2002-03-26  

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