1999 Fiscal Year Final Research Report Summary
Sialographic sonography Establishment of a new diagnostic method in salivary gland diseases
| Project/Area Number |
10557171
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
病態科学系歯学(含放射線系歯学)
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| Research Institution | KYUSHU UNIVERSITY |
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Principal Investigator |
YOSHINO(SHIMIZU) Mayumi (清水 真弓) Fac.Dentistry, Dept.Oral and Maxillofacial Radiology, KYUSHU UNIVERSITY Research Associate, 歯学部, 助手 (50253464)
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| Co-Investigator(Kenkyū-buntansha) |
TSUBONE Izumi Fukuda Denshi Co.Ltd., Sonographic Section, Researcher, 超音波事業部, 研究員
TOKUMORI Kenji Fac.Dentistry, Dept.Oral and Maxillofacial Radiology, KYUSHU UNIVERSITY Research Associate, 歯学部, 助手 (40253463)
YOSHIURA Kazunori Fac.Dentistry, Dept.Oral and Maxillofacial Radiology, KYUSHU UNIVERSITY Associate Professor, 歯学部, 助教授 (20210643)
CHIKUI Tohru Fac. Dentistry, Dept.Oral and Maxillofacial Radiology, KYUSHU UNIVERSITY Research Associate, 歯学部, 助手 (10295090)
HARIYA Yasushi Fac. Dentistry, Dept.Oral and Maxillofacial Radiology, KYUSHU UNIVERSITY Resident, 歯学部, 医員
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| Project Period (FY) |
1998 – 1999
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| Keywords | ultrasonography / sialography / Doppler studies / experimental |
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| Research Abstract |
Aims To analyze potential contrast media for a new diagnostic method having merits of both sialography and sonography.
Methods Saline and various contrast media (Urografin 76% ; 100%, 90%, and 67% Lipiodol Ultra-Fluide ; 67% Lipiodol Ultra-Fluide with emulsifier ; 5% and 1% barium sulfate ; and Levovist) were injected into thin tubes (0.5mm and 0.25mm diameter) at about 0.001 - 0.1 ml/sec. Ultrasonography was performed with a diagnostic ultrasound imaging system (Squoia 512, Acuson Co, USA) and the pulsed Doppler imaging was obtained, All images were transferred to a personal computer and analyzed with an image processing software, NIH Image. A rectangular region of interest (ROI) was selected in a pulsed image and the sum of the gray-levels of all pixels in the ROI was calculated for representing Doppler signal intensities. The relationship between Doppler signal intensity and the kind, concentration and velocity of the fluid were analyzed.
Results Levovist, 90% and 67% Lipiodol Ultra-Fluide, and the barium sulfate solutions produced Doppler signals. The mixture of Lipiodol Ultra-Fluide and saline showed high signals at any concentration in contrast to the barium sulfate solutions. Signals could be observed at any speed, from the speed of normal sialography down to 0.001 ml/sec, and there was a proportional relationship between signal intensity and velocity for all fluids producing signals.
Conclusions As we could obtain high signals with several fluids, the diagnostic usefulness of sialographic sonography should be assessed clinically.
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