1999 Fiscal Year Final Research Report Summary
PATHOLOGY OF PEDIATRIC LUMBAR ENDPLATE LESION, BIOMECHANICAL, BIOCHEMICAL, AND MOLECULAR BIOLOGICAL EVALUATION.
| Project/Area Number |
10671363
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
KATOH Shinsuke DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, ASSOCIATE PROFESSOR, 医学部, 助教授 (30243687)
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| Co-Investigator(Kenkyū-buntansha) |
SAIRYO Koichi DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, LECTURER, 医学部, 講師 (10304528)
YASUOKA Susumu DEPARTMENT OF NURSING, SCHOOL OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKUSHIMA, PROFESSOR, 医療技術短期大学部, 教授 (30035414)
IKATA Takaaki DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, PROFESSOR, 医学部, 教授 (80108860)
HAMADA Yoshitaka DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, CLINICAL FELLOW, 医学部・附属病院, 医員
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| Project Period (FY) |
1998 – 1999
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| Keywords | ADOLESCENTS / LUMBAR SPINE / ENDPLATE / SPONDYLOLYSIS / SPONDYLOLISTHESIS / BIOMECHANICS |
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| Research Abstract |
The failure in lumbar kinematics caused by pars defects is considered to be important factor for the subsequent spinal disorders such as bony deformity and slippage. Clinically, we investigated the kinematics of pediatric lumbar spine with or without pars defects with special reference to the instantaneous axis of rotation (IAR) during lumbar flexion to extension motion. The results suggested that movements of the vertebrae with early stage pars defects may be close to that of normal vertebrae ; whereas, in the progressive and terminal stages of spondylolysis, IAR deviated compared to the normal spine, indicating the failure in lumbar kinematics as the stage of the pars defects advanced. Biomechanically, we evaluated load-displacement behavior under anterior shear loading in the spine with or without pars defects, and found that under such loading in the spine without the pars defects the posterior elements, which showed high rigidity and strength, mostly supported the loading. While in the spine with pars defects, anterior element, which showed comparatively less rigidity and strength, directiy supported the loading. From those clinical and biomechanical viewpoints, we concluded that the failure in the lumbar kinematics occurred in the lumbar spine with pars defects.
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