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2000 Fiscal Year Final Research Report Summary

EPIDEMIOLOGICAL STUDY ON DENTAL STATUS AND TEMPOROMANDIBULAR JOINT IN SUBJECTS WITH RHEUMATOID ARTHRITIS

Research Project

Project/Area Number 10671944
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 矯正・小児・社会系歯学
Research InstitutionKYUSHU DENTAL COLLEGE

Principal Investigator

TAKEHARA Tadamichi  KYUSHU DENTAL COLLEGE, DEPARTMENT OF PREVENTIVE DENTISTRY, PROFESSOR, 歯学部, 教授 (00038879)

Project Period (FY) 1998 – 2000
KeywordsRHEUMATOID ARTHRITIS / TEMPOROMANDIBULAR DISORDERS / DENTAL STATUS
Research Abstract

In order to understand the dental and temporomandibular joint (TMJ) in subjects with rheumatoid arthritis, 142 female patients were compared with 143 control subjects of the same age. The number of remaining teeth and edentulous rate were significantly lower in the RA group than non-RA group. Meanwhile, the number of DMF teeth, as well as frequency of complete denture and removable partial dentures were significantly higher in the RA group. In RA, the incidence of subjective symptoms was 1.4% for pain in the TMJ, 4.9% for pain on mouth opening, and 14.8% for difficulty with mouth opening. Further, signs of TMJ tenderness were found in 9.2%, clicking in 12.7%, and crepitus in 35.9% of those patients. A significantly greater number of subjects who demonstrated crepitus were found in the RA group than the non-RA group. As for temporomandibular disorders (TMD), the incidence was 67.6% in the RA group and 32.9% in the non-RA group. The occurrence of degenerative joint disorders was most frequent among patients with TMD, which was found to correlate with Steinbrocker's stage and RA disease duration.

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] Akifusa,S.,Ohguchi,M et al: "Increase in Bcl-2 level promoted by CD40 ligation correlates with inhibition of B cell opoptosis induced by vacuolar trpe H+ ATP ase inhibitor"Exp.Cell Res. 238. 82-89 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ansai,T.,Awano,S. et al.: "Purification and characterization of alkaline phosphataes containing phosphotyrosyl phosphatase activity from the bacterium Prevottella intermedia"FEBS Lett.. 428. 157-160 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Katoh,Y.,Ansai,T. et al: "A comparison of DA1 scores and characteristics of occlusal traits in three ethnic groups of Asian Origin."Int.Dent.J.. 48. 405-411 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Chen,X.,Ansai,T. et al.: "Isolation, cloning, and expression of an acid phosha tase containing phos photyrosyl phosphatase activity from Prevotella intermedia"J Bacteriol. 181. 7107-7114 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Awano,S.,Ansai,T., et al: "Sequencing, expression and biochemical characterization of Porphyromones gingivalis pepO gene encoding a protein homologous to human"FEBS Lett. 460. 139-144 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ansai,T.,Tahara,A., et al.: "Influence of initial colonization of mutans streptococci on caries hazard in Japanese Preschool children"Rediatr. Dent.. 22. 377-380 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ansai,T.,and Takehara T: "Recent Research Developments in Microbiology"Research Signpost (印刷中). (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Akifusa, S., Ohguchi, M., Koseki, T., Nara, K., Semba, I., Yamato, K., Okahashi, N., Merino, R., Nunez, G., Hanada, N., Takehara, T.and Nishihara, T.: "Increase in Bcl-2 level promoted by CD40 ligation correlates with inhibition of B cell apoptosis induced by vacuolar type H+-ATPase inhibitor."Exp.Cell Res. 238. 82-89 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ansai, T., Awano, S., Chen, X., Fuchi, T., Arimoto, T., Akifusa, S.and Takehara, T.: "Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia."FEBS Lett.. 428. 157-160 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Katoh, Y., Ansai, T., Takehara, T., Yamashita, Y., Miyazaki, H., Jenny, J.and Cons, N.: "A comparison of DAI scores and characteristics of occlusal traits in three ethnic groups of Asian origin."Int.Dent.J.. 48. 405-411 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Chen, X., Ansai, T., Awano, S., Iida, T., Barik, S.and Takehara, T.: "Isolation, cloning, and expression of an acid phosphatase containing phosphotyrosyl phosphatase activity from Prevotella intermedia."J.Bacteriol.. 181. 7107-7114 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Awano, S., Ansai, T., Mochizuki, H., Yu, W., Tanzawa, K., Turner, AJ.and Takehara, T.: "Sequencing, expression and biochemical characterization of the Porphyromonas gingivalis pepO gene encoding a protein homologous to human endothelin-converting enzyme."FEBS Lett.. 460. 139-144 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ansai, T., Tahara, A., Ikeda, M., Katoh, Y., Miyazaki, H., and Takehara, T.: "Influence of initial colonization of mutans streptococci on caries hazard in Japanese preschool children."Pediatr.Dent.. 22. 377-380 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2002-03-26  

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