2001 Fiscal Year Final Research Report Summary

Degradation of Adhesive Restorations and Release of Endocrine Disrupter

Research Project

Project/Area Number	11470401
Research Category	Grant-in-Aid for Scientific Research (B)
Allocation Type	Single-year Grants
Section	一般
Research Field	Conservative dentistry
Research Institution	HOKKAIDO UNIVERSITY
Principal Investigator	SANO Hidehiko Hokkaido Univ., Grad School of Dent, Prof., 大学院・歯学研究科科, 教授 (90205998)
Co-Investigator(Kenkyū-buntansha)	KOBAYASHI Yoichi Hokkaido Univ., Dent., Hospital, Lecturer, 歯学部・附属病院, 助手 (80231322) TANAKA Toru Hokkaido Univ., Grad School of Dent., Assist. Prof., 大学院・歯学研究科科, 助手 (90179771) UNO Shigeru Hokkaido Univ., Dent. Hospital, Lecturer, 歯学部・附属病院, 講師 (00168733) KAWAMOTO Chihara Hokkaido Univ., Dent., Hospital, Assist. Prof., 歯学部・附属病院, 助手 (60301909) NODA Mamoru Hokkaido Unjv, Grad School of Dent., Assist. Prof., 大学院・歯学研究科科, 助手 (10301889)
Project Period (FY)	1999 – 2001
Keywords	Ahesion / Degradation / Endocrine Disruptor
Research Abstract	The results of the research project reviled that the adhesive interface degraded over time. Moist bonding systems showed greater degradation with the extraction of resin within the hybrid layer and depletion of collagen fibrils compared to self-etching systems both in vivo and in vitro. Release of endocrine disrupter from resins were undetectable from both short- and long-term experiment in vivo.

(4 results)