2001 Fiscal Year Final Research Report Summary
The Fundamental Research on the Prophylaxis of Cyclospora Infectious Disease in Water Supply
| Project/Area Number |
11480154
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
環境保全
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| Research Institution | Tohoku Gakuin University |
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Principal Investigator |
ISHIBASHI Yoshinobu Tohoku Gakuin University, Faculty of Engineering, Professor, 工学部, 教授 (10111246)
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| Co-Investigator(Kenkyū-buntansha) |
KUNIKANE Shoichi National Institute of Public Health, Director, 水道工学部, 部長 (90083740)
OMURA Tatsuo Tohoku University, Graduate School of Engineering, Professor, 大学院・工学系研究科, 教授 (30111248)
OHGAKI Shinnichiro The University of Tokyo, Graduate School of Engineering, Professor, 大学院・工学系研究科, 教授 (20005549)
KIMURA Kenji Maezawa Industries Inc., Managing Director, エンジニアリング事業部, 部長
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| Project Period (FY) |
1999 – 2001
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| Keywords | Cyclospora / Traveler's diarrhea / Protozoa / Chlorine tolerant / Water supply |
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| Research Abstract |
Cyclospora is the same newly-tisen protozoa as Cryptosporidium. Its infection route is a contaminated tap water and foods and cyclospriasis shows symptoms of water-like diarrhea. Unlike Cryptosporidium a mass outbreak has not occurred in Japan. However, seven cases of cyclospriasis are reported as import infectious disease. There is a possibility that Cyclospora takes a risk of mass outbreak through water supply. Generally, research of Cyclospora is just started and knowledge is not enough. The purpose of this research was carried out to get the fundamental knowledge for cyclospriasis prevention.
As the beginning of the study, information retrieval, detection methods of cyclospora oocyst and infection and multiplication using cancer cells were investigated. It took three years for the last experiment. In the final year, cyclospora was identified as C. cayetanensis using genetic analysis. Existence of Cyclospora and Cryptospridium oocyst and Giarrdia cyst in aquatic environment and wastewater, ultraviolet irradiation for inactivation etc. were examined.
On the other hand, we went to Nepal several times, where disease rate is high, and made an inspection of the state of infection.
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