2000 Fiscal Year Final Research Report Summary
1,6-Remote Asymmetric Induction in ε-Substituted α, γ-dienones
| Project/Area Number |
11640553
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Kurashiki University of Science and the Arts |
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Principal Investigator |
SATO Tsuneo Kurashiki University of Science and the Arts, College of Science and Industrial Technology, Professor, 産業科学技術学部, 教授 (80183383)
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| Project Period (FY) |
1999 – 2000
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| Keywords | remore asymmetric induction / substituent effect / ε-substituted-α, γ-dienone / reduction / alkylation |
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| Research Abstract |
1. (4E,6E)-2,2,9,9-Tetramethyl-4,6-decadien-3-ones having five kinds of heteroatom-substituents at 8 position were synthesized in multiple steps and their 1,6-remote asymmetric reductions were examined with a series of reducing agents at -78 ℃.
2. The structures of ε-substituted α, γ-dienones described above in solution at room temperature were examined by means of IR (CCl_4) and ^1H NMR (CDCl_3).
3. No 1,6-remote asymmetric inductions were observed in the reactions of (2E,4E)-7,7-dimethyl-6-phenylthio-2,4-octadienal with t-butyl organometallic reagents.
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