2000 Fiscal Year Final Research Report Summary
Morphological correlates of principal components of current source density profile in the frog optic tectum
| Project/Area Number |
11640682
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
動物生理・代謝
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| Research Institution | Kyushu Institute of Technology |
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Principal Investigator |
NAKAGAWA Hideki Kyushsu Institute of Technology, Graduate School of Life Science and Systems Engineering, Associate Professor, 生命体工学研究科, 助教授 (80212083)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Nobuyoshi Kyushsu Institute of Technology, Graduate School of Life Science and Systems Engineering, Professor, 生命体工学研究科, 教授 (80029545)
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| Project Period (FY) |
1999 – 2000
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| Keywords | optic tectum / Golgi staining / principal component analysis / frog / neuron / morphological property / physiological principal component / morphological principal component |
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| Research Abstract |
In the frog Rana catesbeiana, we have applied principal component analysis (PCA) to characterize the spatiotemporal current source density (CSD) patterns generated by distinct neuronal populations producing the tectal neuronal activity and showed that 84 per cent of the variance of the CSD was accounted for by the first three principal components (PCs).
Here, to demonstrate their morphological correlates, we also applied PCA to 21 morphological parameters obtained from 40 Golgi-stained tectal neurons. The analysis showed that 80 per cent of the variance of measured morphological parameters was accounted for by the first six PCs. Judging from the component loadings of each PCs concerning each morphological parameters, possible morphological correlates of each PCs are proposed as follows. PC1 corresponded to large tectal neurons with radially expanding dendrites and large cell bodies. PC2 corresponded to small tectal neurons with vertically expanding short dendrites. PC3 and PC4 corresponded to tectal neurons with vertical dendrites expanding up to the tectal surface and cell bodies in layer 6 or deeper, and those with vertically expanding dendrites and cell bodies in layer 8, respectively. Finally, PC5 and PC6 corresponded to tectal neurons with thin dendrites branching profoundly, and those with symmetrical branching pattern and many basal branches, respectively. Based on these findings, we concluded that physiological PC1, PC2 and PC3 corresponded to morphological PC3, PC4 and PC2, respectively.
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Research Products
(14 results)
