2001 Fiscal Year Final Research Report Summary
Experimental study about vascularized tracheo-laryngeal transfer
| Project/Area Number |
11671781
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
HOSOKAWA Ko Osaka University Graduated School of Medicine, Professor, 医学系研究科, 教授 (20181498)
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| Project Period (FY) |
1999 – 2001
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| Keywords | double headed rat / head and neck transplantation / tracheo-laryngeal transplantation |
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| Research Abstract |
This experiment was designed to promote the research about vascularized tracheo-laryngeal transfer in animals and brought following productions.
1) A rat model of extended laryngeal transplantation combined with a tongue for clinical functional recovery was developed. In this model rats the viability of the transplanted organs was stable and survival rate of recipient was very high.
2) A new rat model transplanted a head and neck without ischemic brain injury was developed. This experimental model will undoubtedly promote not only the research of vascularized tracheo-laryngeal transfer but also various fields of research about head and neck region.
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