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2001 Fiscal Year Final Research Report Summary

Study on Whether Exercise Increases Protein Requirement

Research Project

Project/Area Number 11680154
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 食生活
Research InstitutionKyoto Koka Women's University Junior College

Principal Investigator

KOTARU Makoto  Koka Women's Junior College, Department of Human Ecology, Professor, 生活環境学科, 教授 (80167402)

Co-Investigator(Kenkyū-buntansha) KANAMOTO RYUHEI  Kyoto Prefecturel University, Faculty of Agriuluture, Associate Professor, 農学部, 助教授 (70147297)
Project Period (FY) 1999 – 2000
Keywordsprotein requirement / exercise / aging / surplus amino acids / serine dehydrates / rat / swimming
Research Abstract

We examined whether exercise increases daily protein requirement. For this purpose, Growing rats (4 weeks old) and mature rats (6 months old) were kept on the diets containing different contents of casein as a protein source. In 25% casein group of growing rats, the largest nitrogen balance and body weight gain were observed and serine dehydratase (SDK) activity in their liver was increased. Mature rats maintained their nitrogen balance on the diets containing more than 10% casein and then the induction of SDH was begun. This suggested that surplus amino acids were a signal for the induction of SDH. Growing rats maintained on the diets containing 6, 9, 12, 18 and 21% casein were forced swimming against a water stream for 20 min a day for 5 days, then feces and urine were collected for following 3 days to determine the nitrogen balance. The body weight gain was larger in exercised group though the significant deference was observed in the groups of rats maintained on 9% and 12% casein diet, The food intakes of these groups were also larger in exercise group. To determine the obligatory nitrogen loss, the nitrogen balance of each rat was plotted against the nitrogen intake. There found a significant correlation between two factors and the regression analysis indicated that the obligatory nitrogen loss was increased by exercise. Interestingly, the nitrogen efficiency, body weight gain/ lg of dietary nitrogen intake, was increased by exercise m 9% and 12% casein group. Liver SDH activity was slightly but significantly increased in exercise group. These results suggested that exercise stimulate protein turnover and increased protein requirement.

Research Products

(2 results)

All Other

All Publications (2 results)

  • [Publications] 金本龍平: "タンパク質必要量とセリン脱水酵素の誘導について"必須アミノ酸研究. 157号. 45-48 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kanamoto Ryuhei: "Protein requirement of growing and mature rats and the induction of serine dehydratase in their liver"JOURNAL, VOLUME-NUMBER, PAGES CONCERNED, YEAR Report of the research committee of essential amino acids(Japan). 157. 45-48 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2003-09-16  

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