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2000 Fiscal Year Final Research Report Summary

ELECTROPHY SIOLOGICAL AND MORHPHOLOGICAL STUDIES ON INTERACTION BETWEEN THE CEREBELLAR AND BASAL GANGLIA INPUTS.-ANALYSIS OF INTEGRATION IN THE CEREBRAL CORTEX-

Research Project

Project/Area Number 11680806
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 神経・脳内生理学
Research InstitutionMIE UNIVERSITY

Principal Investigator

YAMAMOTO Tetsuro  Mie University Faculty of Medicine, Professor -> 三重大学, 医学部, 教授 (00127002)

Co-Investigator(Kenkyū-buntansha) KAYAHARA Tetsuro  Mie University Faculty of Medicine, Lecturer, 医学部, 講師 (20024705)
SHIBUYA Hiroshi  Mie University Faculty of Medicine, Assistant, 医学部, 助手 (60262622)
NISHIMURA Yoshihiro  Mie University Faculty of Medicine, Associate Professor, 医学部, 助教授 (40172704)
Project Period (FY) 1999 – 2000
KeywordsBASAL GANGLIA / CEREBELLAR NUCLEI / MOTOR CORTEX / INTRACELLULAR RECORDING / INTERACTION / MOTOR CONTROL / MEMBRANE POTENTIAL CHANGES
Research Abstract

Intracellular recordings and staining were performed from pyramidal neurons of motor cortex and related areas in cats, monkeys and rats to investigate the interaction between the cerebellar and basal ganglia inputs. Experiments were done under pentobarbital anesthesia in in vivo preparations on stimulation of cerebellar nuclei and basal ganglia. To obtain the morphological data, we also used anterograde tract tracing method with various tracers. In the beginning of the project, we tried to record from two neurons simultaneously, but it was rather difficult from technical point of view, so we compared the responsiveness of neurons in the motor cortex and those of premotor areas as well as in vitro preparations.

Research Products

(19 results)

All Other

All Publications

  • [Publications] Kitagawa,F., et al.: "Activity-dependent slow hyerpolarization in cat sensorimotor cortex in vitro."Brain Research. 869. 69-77 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakano,K. et al.: "Neural circuit and function organization of the striatum."J.Neurology. 247(Suppl.5). 1-15 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakano,K.: "Neural circuit and topographic organization of the basal ganglia and related regions."Brain and Development. 22. S5-S16 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hong L.et al.: "Morphological evidence for a vestibulo-thalamo-striatal pathway via the parafascicular nucleus in the rat."Brain Research. 872. 208-214 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tutsumi,T. et al.: "Proline-and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses."J.Biological Chemistry. 275. 9157-9162 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中野勝磨: "視床の構造:形態面から"Clinical Neuroscience. 18(8). 18-21 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中野勝磨: "図説:大脳基底核の構造と機能"日本臨床. 58(10). 2-6 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中野勝磨: "大脳基底核の機能形態学"Kinesis. 15(2). 10-13 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kumazawa,Y. et al.: "Opiates modulate facial motoneurons in rats."Neuroscience Research. Supple24. S80 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Lin,M. et al.: "Properties of voltage dependent potassium currents in acutely isolated rat oculomotor neurons."Neuroscience Research. Supple24. S82 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shibuya,H. et al.: "Fiber connections of the rat rostral claustrum : emotional aspect of pain and motorfunction."Neuroscience Research. Supple24. S111 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kitagawa, F., et al.: "Activity-dependent slow hyperpolarization in cat sensorimotor cortex in vitro."Brain Research. 869. 69-77 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakano, K.et al.: "Neural circuit and function organization of the striatum."J.Neurology. 247(Suppl.5). 1-15 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakano, K.: "Neural circuit and topographic organization of the basal ganglia and related regions."Brain and Development. 22. S5-S16 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hong L.et al.: "Morphological evidence for a vestibulo-thalamo-striatal pathway via the parafascicular nucleus in the rat."Brain Research. 872. 208-214 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tutsumi, T.et al.: "Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses."J.Biological Chemistry. 9157-9162 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kumazawa, Y.et al.: "Opiates modulate facial motoneurons in rats."Neuroscience Research. Supple 24. S80 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Lin, M.et al.: "Properties of voltage dependent potassium currents in acutely isolated rat oculomotor neurons."Neuroscience Research. Supple 24. S82 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shibuya, H.et al.: "Fiber connections of the rat rostral claustrum : emotional aspect of pain and motor function."Neurosicence Research. Supple 24. S111 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2002-03-25  

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