2000 Fiscal Year Annual Research Report

紫外レーザアブレーションのナノ秒時間ゲート分光による不純物濃度分布測定

Research Project

Project/Area Number	11875015
Research Institution	Osaka University
Principal Investigator	春名正光大阪大学, 医学部, 教授 (20029333)
Co-Investigator(Kenkyū-buntansha)	裏升吾大阪大学, 大学院・工学研究科, 助手 (10193955)
Keywords	紫外レーザアブレーション / ナノ秒時間ゲート分光 / 不純物分布測定 / 光コヒーレンストモグラフィ / 白色干渉計
Research Abstract	前年度に、ナノ秒時間ゲート分光法を用いて、大気中でイオン交換ガラスの厚さ方向のK,Na分布が測定できることを実証した。今年度は、不純物分布測定においてμmオーダーの空間分解能を確保するために、超高分解能OCT(光コヒーレンストモグラフィ)を実現し、レーザアブレーションとOCTイメージング系との融合を試みた。 (1)ハロゲンランプ光をGIファイバで空間フィルタリングし、これを光源とする白色干渉計で、両干渉アームの波長分散を補償して、コヒーレンス長1.3μmを得た。 (2)上記の干渉計を用いて、アブレーション深さ10μm前後のサンプル表面のOCT断層像の取得に成功した。 (3)SLDを光源とするOCTイメージング系で、UVレーザアブレーションされた生体サンプル表面の断層像を順次取得することによって、空間分解能〜10μmで生体サンプルのCa分布測定が行なえることを実証した。 (4)光ファイバ干渉計を用いて、上記のOCTイメージング系を小型・安定化し、OCTとレーザアブレーション光学系の融合を試みている。 (5)OCTによって、アブレーションされたサンプル表面周辺の損傷を明確に観察できる。とくにガラスは損傷を受けやすい。この事実をもとに、OCTとレーザブレーションを組み合わせた新たな精密加工法を示唆した。

Research Products

(15 results)

All Other

All Publications (15 results)

[Publications] Masamitsu Haruna: "Detection of phase transition of a biological membrane by precise refractive-index measurement based on the low coherence interferometry"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.3915. 188-193 (2000)
[Publications] Masamitsu Haruna: "Calcium detection of human hair and nail by the nanosecond time-gated spectroscopy of laser-ablation plume"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.3917. 87-92 (2000)
[Publications] Masamitsu Haruna: "Optical reflection imaging for display of 2-D refractive index distribution along the geometrical thickness"OSA Biomed.Topical Meetings, Tech.Dig.. MB5. 194-196 (2000)
[Publications] Masato Ohmi: "Nanosecond time-gated spectroscopy of laser-ablation plume of human hair to detect calcium for potential diagnoses"Optical Review. Vol.7,No.4. 353-357 (2000)
[Publications] Koji Yoden: "An approach to optical reflection tomography along the geometrical thickness"Optical Review. Vol.7,No.5. 402-405 (2000)
[Publications] Hideki Maruyama: "Simultaneous measurement of refractive index and thickness by low coherence interferometry considering chromatic dispersion of index"Optical Review. Vol.7,No.5. 468-472 (2000)
[Publications] Masato Ohmi: "In vitro simultaneous measurement of refractive index and thickness by low coherence interferometry"IEEE Trans.Biomed.Eng.. Vol.47,No.9. 1266-1270 (2000)
[Publications] Shogo Inoue: "Ultra low coherence interferometry for determination of refractive index and thickness of transparent plate"14th Int'l Conf.Opt.Fiber Sensors (OFS-14). P2-21. 468-471 (2000)
[Publications] Masato Ohmi: "Optical reflection imaging along the geometrical thickness by combination of coherence-gate and confocal imagings"14th Int'l Conf.Opt.Fiber Sersors (OFS-14). Th1-3. 288-291 (2000)
[Publications] 春名正光: "光コヒーレンストモグラフィ(OCT)-原理と開発の現状-"臨床消化器内科. Vol.16,No.1. 131-133 (2001)
[Publications] 春名正光: "生体のマイクロ光診断と実サイズ光トモグラフィ"O plus E. Vol.23,No.1. 86-89 (2001)
[Publications] Masamitsu Haruna: "In situ tomographic observation of tissue surface during laser ablation"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.4257(to be published). (2001)
[Publications] Masato Ohmi: "Optical reflection tomography along the geometrical thickness"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.4251(to be published). (2001)
[Publications] Ryuh Konoshita: "Measurement of calcium of biological tissues along the depth by laser ablation"Conf.Lasers & Electro-Optics (CLEO/PR2001). (to be published). (2001)
[Publications] Masato Ohmi: "Optical reflection tomography along the geometrical thickness toward in vivo imaging of biological tissue"Conf.Lasers & Electro-Optics (CLEO/PR2001). (to be published). (2001)

2000 Fiscal Year Annual Research Report

紫外レーザアブレーションのナノ秒時間ゲート分光による不純物濃度分布測定

Principal Investigator

春名 正光 大阪大学, 医学部, 教授 (20029333)

Research Products

[Publications] Masamitsu Haruna: "Detection of phase transition of a biological membrane by precise refractive-index measurement based on the low coherence interferometry"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.3915. 188-193 (2000)

[Publications] Masamitsu Haruna: "Calcium detection of human hair and nail by the nanosecond time-gated spectroscopy of laser-ablation plume"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.3917. 87-92 (2000)

[Publications] Masamitsu Haruna: "Optical reflection imaging for display of 2-D refractive index distribution along the geometrical thickness"OSA Biomed.Topical Meetings, Tech.Dig.. MB5. 194-196 (2000)

[Publications] Masato Ohmi: "Nanosecond time-gated spectroscopy of laser-ablation plume of human hair to detect calcium for potential diagnoses"Optical Review. Vol.7,No.4. 353-357 (2000)

[Publications] Koji Yoden: "An approach to optical reflection tomography along the geometrical thickness"Optical Review. Vol.7,No.5. 402-405 (2000)

[Publications] Hideki Maruyama: "Simultaneous measurement of refractive index and thickness by low coherence interferometry considering chromatic dispersion of index"Optical Review. Vol.7,No.5. 468-472 (2000)

[Publications] Masato Ohmi: "In vitro simultaneous measurement of refractive index and thickness by low coherence interferometry"IEEE Trans.Biomed.Eng.. Vol.47,No.9. 1266-1270 (2000)

[Publications] Shogo Inoue: "Ultra low coherence interferometry for determination of refractive index and thickness of transparent plate"14th Int'l Conf.Opt.Fiber Sensors (OFS-14). P2-21. 468-471 (2000)

[Publications] Masato Ohmi: "Optical reflection imaging along the geometrical thickness by combination of coherence-gate and confocal imagings"14th Int'l Conf.Opt.Fiber Sersors (OFS-14). Th1-3. 288-291 (2000)

[Publications] 春名正光: "光コヒーレンストモグラフィ(OCT)-原理と開発の現状-"臨床消化器内科. Vol.16,No.1. 131-133 (2001)

[Publications] 春名正光: "生体のマイクロ光診断と実サイズ光トモグラフィ"O plus E. Vol.23,No.1. 86-89 (2001)

[Publications] Masamitsu Haruna: "In situ tomographic observation of tissue surface during laser ablation"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.4257(to be published). (2001)

[Publications] Masato Ohmi: "Optical reflection tomography along the geometrical thickness"Proc.SPIE, Progress in Biomed.Opt.& Imaging. Vol.4251(to be published). (2001)

[Publications] Ryuh Konoshita: "Measurement of calcium of biological tissues along the depth by laser ablation"Conf.Lasers & Electro-Optics (CLEO/PR2001). (to be published). (2001)

[Publications] Masato Ohmi: "Optical reflection tomography along the geometrical thickness toward in vivo imaging of biological tissue"Conf.Lasers & Electro-Optics (CLEO/PR2001). (to be published). (2001)

春名正光大阪大学, 医学部, 教授 (20029333)