Cell Cycle Control

2005 Fiscal Year Final Research Report Summary

• Project/Area Number: 12060101
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: The University of Tokyo
• Principal Investigator: OKAYAMA Hiroto The University of Tokyo, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授 (40111950)
• Co-Investigator(Kenkyū-buntansha): KISHIMOTO Takeo Tolyo Institute of Technology, Grad Sch Biosci. & Biotech, Professor, 大学院生命理工学研究科, 教授 (00124222) ; TOH-E Akio The University of Tokyo, Department of Biological Sciences, Professor, 大学院理学系研究科, 教授 (90029249) ; TSUBATA Takeshi Tokyo Medical and Dental University, Laboratory of Immunology, School of Biomedical Science, Professor, 疾患生命科学研究部, 教授 (80197756) ; NISHIDA Yasuyoshi Nagoya University, Graduate School of Science, Professor, 大学院理学研究科, 教授 (50107059) ; OHYA Yoshikazu The University of Tokyo, Graduate School of Frontier Sciences, Department of Integrated Biosciences, Professor, 大学院新領域創成科学研究科, 教授 (20183767)
• Project Period (FY): 2000 – 2005
• Keywords: cell cycle control / checkpoint control / Sphase onset control / cell death control / cell differentiation control

Research Abstract

An administrative group is formed within the key members to promote efficient implementation of the research funded by the Japanese Government called "Cell Cycle Control". The major activities of this administrative group are to oversight the entire team, provide extra funds to those that are expected to make a rapid progress and hold international symposia and intra-mural conferences for progress report, the latter two to facilitate exchanges of unpublished information.
The titles and venues of the international symposia held every year are "Gl Control" at Tokyo, " M-Phase Progression" at Kanagawa, Proteolysis on Cellular Regulation at Tokyo, "Cell Death, Cell Cycling and Cell Senescence" at Chiba and "Cell Cycle and Development" at Nagoya. Every year about 10 each young top-class scientists were invited from abroad and domestic to speak before 100-200 audiences from all over Japan.
On the other hand, the intra-mural conferences for progress report held every year served as the unique opportunity to exchange unpublished information and evaluate rates of progress among members. The last two conferences were held at Hokkaido and Miyazaki, having enough presentation and discussion time for each member.

Research Products

• [Journal Article] Nonviral gene delivery by tetraamino fullerene. (2006)
  • Author(s): Isobe, H., Nakanishi, W., Tomita, N., Jinno, S., Okayama, H., Nakamura, E.
  • Journal Title: Mol. Pham. 3 Pages: 124-134
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. (2006)
  • Author(s): Nishiyama A, Muraki K, Saito M, Ohsumi K, Kishimoto T, Ishikawa F.
  • Journal Title: EMBO J. 25 Pages: 575-584
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] p90Rsk is required for G1 phase arrest unfertilized starfish eggs. (2006)
  • Author(s): Mori, M., Hara, M., Tachibana, K., Kishimoto, T.
  • Journal Title: Development 133 Pages: 1823-1830
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identifying novel subustrates for mouse CDK5 using the yeast Saccharomyces cerevisiae. (2006)
  • Author(s): Horiuchi, Y., Asada, A., Hisanaga, S., Toh-e, Nishizawa, M.
  • Journal Title: Genes Cells 11 Pages: 1393-1404
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] The tumor suppressor p53 is not required for antigen receptor-mediated apoptosis of B lymphocytes. (2006)
  • Author(s): Devi, S.S., Hagiyama, H., Adachi, T., Miyasaka, N., Tsubata, T.
  • Journal Title: Signal Transduction 6 Pages: 54-61
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Bispecific antibodies against modified protein and DNA with oxidized lipids. (2006)
  • Author(s): Akagawa M, Ito S, Toyoda K, Ishi Y, Tatsuda E, Shibata T, Kawai, Y., Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K.
  • Journal Title: Proc. Natl. Acad. Sci. USA. 103 Pages: 6160-6165
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mi-2 chromatin remodeling factor functions in sensory organ development through proneural gene repression in Drosophila. (2006)
  • Author(s): Yamasaki, Y., Nishida, Y.
  • Journal Title: Develop. Growth Differ. 48 Pages: 411-418
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Evaluation of image processing programs for accurate measurement of budding and fission yeast morphology. (2006)
  • Author(s): Suzuki, G., et al.
  • Journal Title: Curr. Genet. 49 Pages: 237-247
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Nonviral gene delivery by tetraamino fullerene. (2006)
  • Author(s): Isobe, H., Nakanishi, W., Tomita, N., Jinno, S., Okayama, H., Nakamura, E.
  • Journal Title: Mol. Pharm. 3 Pages: 124-134
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. (2006)
  • Author(s): Nishiyama, A., Muraki, K., Saito, M., Ohsumi, K., Kishimoto, T., Ishikawa, F.
  • Journal Title: EMBO J. 25 Pages: 575-584
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] p90Rsk is required for Gl phase arrest in unfertilized starfish eggs. (2006)
  • Author(s): Mori, M., Hara, M., Tachibana, K., Kishimoto, T.
  • Journal Title: Development 133 Pages: 1823-1830
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Identifying novel substrates for mouse CDK5 using the yeast Saccharomyces cerevisiae. (2006)
  • Author(s): Horiuchi, Y., Asada, A., Hisanaga, S., Toh-e, A., Nishizawa, M.
  • Journal Title: Genes Cells 11 Pages: 1393-1404
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Bispecific antibodies against modified protein and DNA with oxidized lipids. (2006)
  • Author(s): Akagawa M, Ito S, Toyoda K, Ishii Y, Tatsuda E, Shibata T, Kawai, Y., Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K.
  • Journal Title: Proc. Natl. Acad. Sci. USA. 103 Pages: 6160-6165
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Evaluation of image processing programs for accurate measurement of budding and fission yeast morphology. (2006)
  • Author(s): Suzuki, G. et al.
  • Journal Title: Curr Genet. 49 Pages: 237-247
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Inhibition of Cdk6 expression through p38 MAP kinase is involved in differentiation of mouse prechondrocyte ATDC5. (2005)
  • Author(s): Moro T, Ogasawara T, Chikuda H, Ikeda T, Ogata N, Maruyama Z, Komori T, Hoshi K, Chung UI, Nakamura K, Okayama H, Kawaguchi H.
  • Journal Title: J. Cell Physiol. 204 Pages: 927-933
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs. (2005)
  • Author(s): Yamamoto, T.M., Iwabuchi, M., Ohsumi, K., Kishimoto, T.
  • Journal Title: Dev. Biol. 279 Pages: 345-355
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs. (2005)
  • Author(s): Shintomi K, Iwabuchi M, Saeki H, Ura K, Kishimoto T, Ohsumi, K.
  • Journal Title: Proc. Natl. Acad. Sci. USA 102 Pages: 8210-8215
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] In memory of Andre Picard : 1950-2004(Obituary). (2005)
  • Author(s): Kishimoto, T.
  • Journal Title: Biol. Cell 97 Pages: 349-350
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cell cycle unleashed (News and Views). (2005)
  • Author(s): Kishimoto, T.
  • Journal Title: Nature 437 Pages: 963-965
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Functional analysis of Rpn6p, a lid component of the 26 S proteasome, using temperature-sensitive rpn6 mutants of the yeast Saccharomyces cerevisiae. (2005)
  • Author(s): Isono, E., Saito, N., Kamata, N., Saeki, Y., Toh-e, A.
  • Journal Title: J Biol Chem. 280 Pages: 6537-6547
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] In vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell. (2005)
  • Author(s): Yasuaki Nito, Akio Tho-e, Hiro-o Hamaguchi
  • Journal Title: J Raman Spectroscopy 36 Pages: 837-839
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] LAS24/KOG1, a component of the TOR complex 1 (TORC1) is needed for resistance to local anesthetic and normal distribution of actin cytoskeleton in yeast. (2005)
  • Author(s): Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akiko Toh-e
  • Journal Title: Genes Genet Syst. 80 Pages: 325-343
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity. (2005)
  • Author(s): Saeki, Y., Isonom, E., Toh-e, A.
  • Journal Title: Method. Enzymol. 399 Pages: 215-227
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Knocking out ubiquitin proteasome system function in vivo and in vitro with genetically encodable tandem ubiquitin. (2005)
  • Author(s): Saeki, Y., Isonom, E., Shimada, M., Kawahara, H., Yokosawa, H., Toh-e, A.
  • Journal Title: Method. Enzymol. 399 Pages: 64-74
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] B cell abnormality and autoimmune disorders. (2005)
  • Author(s): Tsubata, T.
  • Journal Title: Autoimmunity 38 Pages: 331-337
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] High-dimensional and large-scale phenotyping of yeast mutants. (2005)
  • Author(s): Ohya, Y., et al.
  • Journal Title: Proc. Natl. Acad. Sci. USA 102 Pages: 19015-19020
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase. (2005)
  • Author(s): Kondoh, O., et al.
  • Journal Title: Biol Pharm Bull. 28 Pages: 2138-2141
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Data Mining Tools for Saccharomyces Cerevisiae Morphological Database. (2005)
  • Author(s): Saito, T., et al.
  • Journal Title: Nuc. Acid Res. 33 Pages: W753-757
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae. (2005)
  • Author(s): Igarashi, R., et al.
  • Journal Title: Cell Struct Funct. 30 Pages: 57-67
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae. (2005)
  • Author(s): Kono, K., et al.
  • Journal Title: Yeast 22 Pages: 129-139
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs : Implications for the molecular pathogenesis of human mitochondrial diseases. (2005)
  • Author(s): Umeda, N., et al.
  • Journal Title: J Biol Chem. 280 Pages: 1613-1624
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs. (2005)
  • Author(s): Shintomi, K., Iwabuchi, M., Saeki, H., Ura, K., Kishimoto, T., Ohsumi, K.
  • Journal Title: Proc. Natl. Acad. Sci. USA 102 Pages: 8210-8215
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] In memory of Andre Picard : 1950-2004 (Obituary). (2005)
  • Author(s): Kishimoto, T.
  • Journal Title: Biol. Cell 97 Pages: 349-350
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] In vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell. (2005)
  • Author(s): Yasuaki Naito, Akio Toh-e, Hiro-o Hamaguchi
  • Journal Title: J Raman Spectroscopy 36 Pages: 837-839
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] LAS24/KOG1, a component of the TOR complex 1 (TORC1) is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast. (2005)
  • Author(s): Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akio Toh-e
  • Journal Title: Genes Genet Syst. 80 Pages: 325-343
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity. (2005)
  • Author(s): Saeki, Y., Isono, E., Toh-e, A.
  • Journal Title: Method. Enzymol. 399 Pages: 215-227
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Knocking out ubiquitin proteasome system function in vivo and in vitro with genetically encodable tandem ubiquitin. (2005)
  • Author(s): Saeki, Y., Isono, E., Shimada, M., Kawahara, H., Yokosawa, H., Toh-e, A.
  • Journal Title: Method. Enzymol. 399 Pages: 64-74
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] High-dimensional and large-scale phenotyping of yeast mutants. (2005)
  • Author(s): Ohya, Y. et al.
  • Journal Title: Proc. Natl. Acad. Sci. USA 102 Pages: 19015-19020
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase. (2005)
  • Author(s): Kondoh, O. et al.
  • Journal Title: Biol Pharm Bull. 28 Pages: 2138-2141
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Data Mining Tools for Saccharomyces Cerevisiae Morphological Database. (2005)
  • Author(s): Saito, T. et al.
  • Journal Title: Nuc.Acid Res. 33 Pages: W753-757
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae. (2005)
  • Author(s): Igarashi, R. et al.
  • Journal Title: Cell Struct Funct. 30 Pages: 57-67
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae. (2005)
  • Author(s): Kono, K. et al.
  • Journal Title: Yeast 22 Pages: 129-139
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs: Implications for the molecular pathogenesis of human mitochondrial diseases. (2005)
  • Author(s): Umeda, N. et al.
  • Journal Title: J Biol Chem. 280 Pages: 1613-1624
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6(Cdk6). (2004)
  • Author(s): Ogasawara, T., Katagiri, M., Yamamoto, A., Hoshi, K., Takato, T., Nakamura, K., Tanaka, S., Okayama, H., Kawaguchi, H.
  • Journal Title: J. Bone Miner. Res. 19 Pages: 1128-1136
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Bone morphogenetic protein-2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6. (2004)
  • Author(s): Ogasawara, T., Kawaguchi, H., Jinno, S., Hoshi, K., Itaka, K., Takato, T., Nakamura, K., Okayama, H.
  • Journal Title: Mol. Cell. Biol. 24 Pages: 6560-6568
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Emil-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest. (2004)
  • Author(s): Ohsumi, K., Koyanagi, A., Yamamoto, T.M., Gotoh, T., Kishimoto, T.
  • Journal Title: Proc. Natl. Acad. Sci. USA 101 Pages: 12531-12536
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] PDK1 is required for the hormonal signalling pathway leading to meiotic resumption in starfish oocytes. (2004)
  • Author(s): Hiraoka, D., Hori-Oshima, S., Fukuhara, T., Tachibana, K, Okumura, E., Kishimoto, T.
  • Journal Title: Dev. Biol. 276 Pages: 330-336
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Morphological and biochemical changes of neurofilaments in aged rat sciatic nerve axons. (2004)
  • Author(s): Uchida A, Tashiro T, Komiya Y, Yorifuji H, Kishimoto T, Hisanaga S.
  • Journal Title: J. Neurochem. 88 Pages: 735-745
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] More than G1 or G2 arrest : Useful starfish oocyte system for investigating skillful MAP kinase. (2004)
  • Author(s): Kishimoto, T.
  • Journal Title: Biol. Cell 96 Pages: 241-244
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Simultaneous yet independent regulation of actin cytoskeleton organization and translation initiation by glucose in Saccharomyces cerevisiae. (2004)
  • Author(s): Uesono, Y, Ashe, P., Toh-e, A.
  • Journal Title: Mol. Biol. Cell 15 Pages: 1544-1556
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Ybr267W is new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae. (2004)
  • Author(s): Iwase, M., Toh-e, A.
  • Journal Title: Cell Struc. Funct. 29 Pages: 1-15
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Yeast Pho85 kinase is required for proper gene expression during the diauxoc shift. (2004)
  • Author(s): Nishizawa, M., Katou, H., Shirahige, K, Toh-e, A.
  • Journal Title: Yeast 21 Pages: 903-918
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Rpn7 is required for the structural integrity of the 26S proteasome of Saccharomyces Cerevisiae (2004)
  • Author(s): Isono, E., et al.
  • Journal Title: J. Biol. Chem. 279 Pages: 27168-27176
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Sem1p is a novel subunit of the 26S proteasome from Saccharomyces cerevisiae. (2004)
  • Author(s): Sone, T., et al.
  • Journal Title: J. Biol. Chem. 279 Pages: 28807-28816
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Intracellularly inducible, ubiquintin hydrolase-insensitive tandem ubiquitins inhibit 26S proteasome activity and cell division. (2004)
  • Author(s): Saeki, Y., et al.
  • Journal Title: Genes Genet. Syst. 79 Pages: 77-86
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage (2004)
  • Author(s): Saeki, Y., et al.
  • Journal Title: Biochem. Biophys. Res. Commun. 320 Pages: 840-845
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in budding yeast. (2004)
  • Author(s): Itoh, T., Toh-e, A., Matsui, Y.
  • Journal Title: EMBO J. 23 Pages: 2520-2530
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Forchlorfenuron, a phenylurea cytokinin, disturbs septin organization in Saccharomyces cerevisiae. (2004)
  • Author(s): Iwase, M., Okada, S., Oguchi, T., Toh-e, A.
  • Journal Title: Genes Genet Syst. 79 Pages: 199-206
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Ectopic CD40 ligand expression on B cells trigger intestinal inflammation. (2004)
  • Author(s): Kawamura T, Knanai T, Dohi T, Uraushihara K, Totsuka T, Iiyama R, Taneda C, Yamazaki M, Nakamura T, Higuchi T, Aiba Y, Tsubata T, Watanabe M.
  • Journal Title: J. Immunol. 172 Pages: 6388-6397
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular interactions regulate BCR signal inhibition by CD22 and CD72. (2004)
  • Author(s): Nitschke, L., Tsubata, T.
  • Journal Title: Trends Immunol. 25 Pages: 543-550
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Armadillo/Pangolin regulates PCNA and DREF promoter activities. (2004)
  • Author(s): Kwon, E., et al.
  • Journal Title: Biochim. Biophys. Acta. 1679 Pages: 256-262
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Dynactin complex is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae. (2004)
  • Author(s): Suzuki, M., et al.
  • Journal Title: Nat. Cell Biol. 6 Pages: 861-871
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A novel mechanism of intragenic complementation between Phe to Ala calmodulin mutations. (2004)
  • Author(s): Okano, H., Ohya, Y.
  • Journal Title: J. Biochem. 135 Pages: 289-295
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cell shape and growth of budding yeast cells in restrictive microenvironments. (2004)
  • Author(s): Suzuki, M., et al.
  • Journal Title: Yeast 21 Pages: 983-989
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular mechanism of vde-initiated intein homing in yeast nuclear genome. (2004)
  • Author(s): Fukuda, T., et al.
  • Journal Title: Adv Biophys. 38 Pages: 215-232
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] SCMD : Saccaromyces cerevisiae morphological database. (2004)
  • Author(s): Saito, T.L., et al.
  • Journal Title: Nuc. Acid Res. 32 Pages: D319-322
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Analysis of the molecular interaction of the farnesyl moiety of transducin through use of a photoreactive farnesyl analog. (2004)
  • Author(s): Hagiwara, K., et al.
  • Journal Title: Biochemstry 43 Pages: 300-309
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Development of Image Processing program for Yeast Cell Morphology. (2004)
  • Author(s): Ohtani, M., et al.
  • Journal Title: J. Bioinfo. Comput. Biol. 1 Pages: 695-709
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6). (2004)
  • Author(s): Ogasawara, T., Katagiri, M., Yamamoto, A., Hoshi, K., Takato, T., Nakamura, K., Tanaka, S., Okayama, H., Kawaguchi, H.
  • Journal Title: J. Bone Miner. Res. 19 Pages: 1128-1136
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] More than Gl or G2 arrest : Useful starfish oocyte system for investigating skillful MAP kinase. (2004)
  • Author(s): Kishimoto, T.
  • Journal Title: Biol. Cell 96 Pages: 241-244
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Simultaneous yet independent regulation of actin cytoskeleton organization and translation initiation by glucose in Saccharomyces cerevisiae. (2004)
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• [Journal Article] Yeast Pho85 kinase is required for proper gene expression during the diauxic shift. (2004)
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• [Journal Article] Rpn7 is required for the structural integrity of the 26S proteasome of Saccharomyces cerevisiae. (2004)
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• [Journal Article] Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division. (2004)
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• [Journal Article] Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage. (2004)
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• [Journal Article] Mmrlp is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast. (2004)
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  • Journal Title: EMBO J. 23 Pages: 2520-2530
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• [Journal Article] Ectopic CD40 ligand expression on B cells trigger intestinal inflammation. (2004)
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  • Journal Title: J. Immunol. 172 Pages: 6388-6397
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• [Journal Article] Dynactin complex is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae. (2004)
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• [Journal Article] Cell shape and growth of budding yeast cells in restrictive microenvironments. (2004)
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  • Journal Title: Yeast 21 Pages: 983-989
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• [Journal Article] Molecular mechanism of vde-initiated intein homing in yeast nuclear genome. (2004)
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  • Journal Title: Nuc. Acid Res. 32 Pages: D319-322
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• [Journal Article] Analysis of the molecular interaction of the farnesyl moiety of transducin through use of a photoreactive farnesyl analog. (2004)
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  • Journal Title: Biochemstry 43 Pages: 300-309
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• [Journal Article] Development of Image Processing Program for Yeast Cell Morphology. (2004)
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  • Journal Title: J. Bioinfo. Comput. Biol. 1 Pages: 695-709
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• [Journal Article] Overexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation. (2003)
  • Author(s): Chen, Q., Lin, J., Jinno, S., Okayama, H.
  • Journal Title: Oncogene 22 Pages: 992-1001
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• [Journal Article] Distinct regulators for Plk1 activation in starfish meiotic and early embryonic cycles. (2003)
  • Author(s): Okano-Uchida, T., Okumura, E., Iwashita, M, Yoshida, H., Tachibana, K., Kishimoto, T.
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• [Journal Article] Localization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytes. (2003)
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  • Journal Title: Mol. Biol. Cell 14 Pages: 4685-4694
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• [Journal Article] Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation. (2003)
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  • Journal Title: J. Neurosci. 23 Pages: 1189-1197
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• [Journal Article] Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. (2003)
  • Author(s): Honma N, Asada A, Takeshita S, Enomoto M, Yamakawa E, Tsutsumi K, Saito T, Satoh T, Itoh H, Kaziro Y, Kishimoto T, Hisanaga S.
  • Journal Title: Biochem. Biophys. Res. Comm. 310 Pages: 398-404
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• [Journal Article] Cell cycle control during meiotic maturation. (2003)
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  • Journal Title: Curr. Opin. Cell Biol. 15 Pages: 654-663
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• [Journal Article] Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeast. (2003)
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• [Journal Article] Comparative analysis of yeast PIAS-type SUMO ligases in vitro and in vivo. (2003)
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  • Journal Title: J. Biochem. 133 Pages: 415-422
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• [Journal Article] Rsp5-Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast. (2003)
  • Author(s): Kaida, D., Toh-e, A., Kikuchi, Y.
  • Journal Title: Biochem. Biophys. Res. Commun. 306 Pages: 1037-1041
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Phosphorelay-regulated degradation of the yeast Ssklp response regulator by the ubiquitin-proteasome system. (2003)
  • Author(s): Sato, N., Kawahara, H., Toh-e, A., Maeda, T.
  • Journal Title: Mol. Cell. Biol. 23 Pages: 6662-6671
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• [Journal Article] Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. (2003)
  • Author(s): Suzuki, A., Kaisyo, T., Ohishi, M., Tsukio-Yamaguschi, M., Tsubata, T., Koni, P.A., Sasaki, T., Mak, T.W., Nakano, T.
  • Journal Title: J. Exp. Med 197 Pages: 657-667
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• [Journal Article] Inhibitory co-receptors activated by antigens but not by aniti immunoglobulinheavy chain antibodies install requirement of co-stimulation through CD40 for survival and proliferation of B cells. (2003)
  • Author(s): Hokazono, Y., Adachi, T., Wabl, M., Tada, N., Amagasa, T., Tsubata T.
  • Journal Title: J. Immunol. 171 Pages: 261-269
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• [Journal Article] Involvement of cell cycle progression in survaival signaling through CD40 inB lymphocyte line Wehi-231. (2003)
  • Author(s): Hirai H, Adachi T, Tsubata T.
  • Journal Title: Cell. Death. Differ 11 Pages: 261-269
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• [Journal Article] Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis. (2003)
  • Author(s): Kwon, E., et al.
  • Journal Title: Gene 309 Pages: 101-116
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• [Journal Article] Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila. (2003)
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  • Journal Title: J. Cell Sci. 116 Pages: 3811-3823
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• [Journal Article] Distinct regulators for Plkl activation in starfish meiotic and early embryonic cycles. (2003)
  • Author(s): Okano-Uchida, T., Okumura, E., Iwashita, M., Yoshida, H., Tachibana, K., Kishimoto, T.
  • Journal Title: EMBOJ. 22 Pages: 5633-5642
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• [Journal Article] Ras recruits mitotic exit regulator Ltel to the bud cortex in budding yeast. (2003)
  • Author(s): Yoshida, S., Ichihashi, R., Toh-e, A.
  • Journal Title: J. Cell Biol. 161 Pages: 889-897
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• [Journal Article] Rsp5-Bull/2 complex is necessary for the HSE-mediated gene expression in budding yeast. (2003)
  • Author(s): Kaida, D., Toh-e, A., Kikuchi, Y.
  • Journal Title: Biochem. Biophys. Res. Commun. 306 Pages: 1037-1041
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. (2003)
  • Author(s): Suzuki, A., Kaisho, T., Ohishi, M., Tsukio-Yamaguchi, M., Tsubata, T., Koni, P.A., Sasaki, T., Mak, T.W., Nakano, T.
  • Journal Title: J. Exp. Med 197 Pages: 657-667
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Inhibitory co-receptors activated by antigens but not by antigen immunoglobulinheavy chain antibodies install requirement of co-stimulation through CD40 for survival and proliferation of B cells. (2003)
  • Author(s): Hokazono, Y., Adachi, T., Wabl, M., Tada, N., Amagasa, T., Tsubata, T.
  • Journal Title: J. Immunol. 171 Pages: 1835-1843
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• [Journal Article] Involvement of cell cycle progression in survaival signaling through CD40 inB lymphocyte line WEHI-231. (2003)
  • Author(s): Hirai, H., Adachi, T., Tsubata, T.
  • Journal Title: Cell. Death. Differ. 11 Pages: 261-269
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis. (2003)
  • Author(s): Kwon, E. et al.
  • Journal Title: Gene 309 Pages: 101・116
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila. (2003)
  • Author(s): Furukawa, K. et al.
  • Journal Title: J. Cell Sci. 116 Pages: 3811-3823
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cdc6 requires anchorage for its expression. (2002)
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  • Journal Title: Oncogene 21 Pages: 1777-1784
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• [Journal Article] Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. (2002)
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  • Journal Title: EMBO J. 21 Pages: 5235-5244
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• [Journal Article] Akt inhibits Mytl in the signalling pathway that leads to meiotic G2/M-phase transition. (2002)
  • Author(s): Okumura, E., Fukuhara, T., Yoshida, H., Hanada, S., Kozutsumi, R, Mori, M., Tachibana, K., Kishimotom, T.
  • Journal Title: Nature Cell Biol. 4 Pages: 111-116
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• [Journal Article] Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle. (2002)
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  • Journal Title: Dev. Biol. 243 Pages: 34-43
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• [Journal Article] Transient inhibition of translation initiation by osmotic stress. (2002)
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• [Journal Article] Normal assembly of 60S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisaie. (2002)
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• [Journal Article] Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression. (2002)
  • Author(s): Kaida, D., Yashiroda, H., Toh-e, A., Kikuchi, Y.
  • Journal Title: Genes Cells 7 Pages: 543-552
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Rpf2p, and evolutionally conserved protein, interacts with ribosomal protein L11 and is essential for processing of 27SB pre-rRNA to 25SrRNA and 60S ribosomal subunit assembly in Saccharomyces cerevisiae. (2002)
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  • Journal Title: J. Biol. Chem. 277 Pages: 28780-28786
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• [Journal Article] Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae. (2002)
  • Author(s): Yoshida, S., Asakawa, K., Toh-e, A.
  • Journal Title: Curr Biol. 12 Pages: 944-950
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• [Journal Article] Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolus. (2002)
  • Author(s): Yoshida, S., Toh-e, A.
  • Journal Title: Biochem. Biophys. Res. Commun. 294 Pages: 687-691
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• [Journal Article] A defect in KLAP104 alleviates the requirement of the MEN (mitotic exit network) gene function in Saccharomyces cerevisiae. (2002)
  • Author(s): Asakawa, K., Toh-e, A.
  • Journal Title: Genetics 162 Pages: 1545-1556
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identification of ubiquitin-like proteins binding subunits of the 26S proteasome. (2002)
  • Author(s): Saeki, Y., Sone, T., Toh-e, A., Yokosawa, H.
  • Journal Title: Biochem. Biophys. Res. Commun. 296 Pages: 813-819
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• [Journal Article] Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae. (2002)
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  • Journal Title: Genes Dev. 16 Pages: 3142-3157
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• [Journal Article] Complex formation with the class V myosin is essential for Ypt11p, a rab type small GTPase, to facilitate the Myo2p function for mitochondrial distribution in the budding yeast. (2002)
  • Author(s): Itoh, T., Watabe, A., Toh-e, A., Matsui, Y.
  • Journal Title: Mol. Cell. Biol. 22 Pages: 7744-7757
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• [Journal Article] Genetic characterization of genes encoding enzymes catalyzing addition of phosphoethanolamine to the glycosylphosphatidylinositol anchor in Saccharomyces cerevisiae. (2002)
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  • Journal Title: Gene. Genet. Syst. 77 Pages: 309-322
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• [Journal Article] The small GTPase Rho3 and diaphanous/forming For3 function in polarized cell growth in fission yeast. (2002)
  • Author(s): Nakano, K, Imai, J., Arai, R., Toh-e, A., Matsui, Y., Mabuchi, I.
  • Journal Title: J. Cell. Sci. 115 Pages: 4629-4639
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cutting Edge : Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. (2002)
  • Author(s): Higuchi T, Aiba Y, Nomura T, Matsuda J, Mocida K, Suzuki M, kikutani H, Honjo T, Nisioka K, Tsubata T.
  • Journal Title: J. Immunol. 168 Pages: 9-12
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• [Journal Article] A distinct signaling pathway used by the IgG-containing B cell an tigen receptor. (2002)
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  • Journal Title: Science. 298 Pages: 2392-2395
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Drosophila myosin phosphatase and its role in dorsal closure. (2002)
  • Author(s): Mizuno, T., Tsutsui, K., Nishida, Y
  • Journal Title: Development 129 Pages: 1215-1223
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Characterization of the dCaMKII-GAL4 driver line Whose expression is controlled by the Drosophila Ca2+/calmodulin- Dependent protein kinase II promoter. (2002)
  • Author(s): Takamatsu, Y., et al.
  • Journal Title: Cell Tissue Res. 310 Pages: 237-252
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mammalian Rcdl is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. (2002)
  • Author(s): Hiroi, N., Ito, T., Yamamoto, H., Ochiya, T., Jinno, S., Okayama, H.
  • Journal Title: EMBO J. 21 Pages: 5235-5244
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Akt inhibits Mytl in the signalling pathway that leads to meiotic G2/M-phase transition. (2002)
  • Author(s): Okumura, E., Fukuhara, T., Yoshida, H., Hanada, S., Kozutsumi, R., Mori, M., Tachibana, K., Kishimoto, T.
  • Journal Title: Nature Cell Biol. 4 Pages: 111-116
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Normal assembly of 60S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisiae. (2002)
  • Author(s): Miyoshi, K., Tsujii, R., Yoshida, H., Maki, Y., Wada, A., Matsui, Y., Toh-e, A., Mizuta, K.
  • Journal Title: J. Biol.Chem. 277 Pages: 18334-18339
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Yeast Whi2 and Psrl-phosphatase form a complex and regulate STRE-mediated gene expression. (2002)
  • Author(s): Kaida, D., Yashiroda, H., Toh-e, A., Kikuchi, Y.
  • Journal Title: Genes Cells 7 Pages: 543-552
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Rpf2p, and evolutionally conserved protein, interacts with ribosomal protein L11 and is essential for processing of 27SB pre-rRNA to 25S rRNA and 60S ribosomal subunit assembly in Saccharomyces cerevisiae. (2002)
  • Author(s): Morita, D., Miyshi, K., Matsui, Y., Toh-e, A., Shinkawa, H., Miyakawa, T., Mizuta, K.
  • Journal Title: J. Biol. Chem. 277 Pages: 28780-28786
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Budding yeast Cdc5 phosphorylates Netl and assists Cdc14 release from the nucleolus. (2002)
  • Author(s): Yoshida, S., Toh-e, A.
  • Journal Title: Biochem. Biophys. Res. Commun 294 Pages: 687-691
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Identification of ubiquitin-like proteins binding subunits of the 26S proteasome. (2002)
  • Author(s): Saeki, Y., Sone, T., Toh-e, A., Yokosawa, H.
  • Journal Title: Biochem. Biophys. Res. Commun. 286 Pages: 813-819
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Complex formation with the class V myosin is essential for Yptllp, a rab type small GTPase, to facilitate the Myo2p function for mitochondrial distribution in the budding yeast. (2002)
  • Author(s): Itoh, T., Watabe, A., Toh-e, A., Matsui, Y.
  • Journal Title: Mol. Cell. Biol. 22 Pages: 7744-7757
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The small GTPase Rho3 and diaphanous/forming For3 function in polarized cell growth in fission yeast. (2002)
  • Author(s): Nakano, K., Imai, J., Arai, R., Toh-e, A., Matsui, Y, Mabuchi, I.
  • Journal Title: J. Cell Sci. 115 Pages: 4629-4639
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cutting Edge : Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. (2002)
  • Author(s): Higuchi T, Aiba Y, Nomura T, Matsuda J, Mochida K, Suzuki M, Kikutani H, Honjo T, Nishioka K, Tsubata T.
  • Journal Title: J. Immunol. 168 Pages: 9-12
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A distinct signaling pathway used by the IgG-containing B cell antigen receptor. (2002)
  • Author(s): Wakabayashi, C., Adachi, T., Wienands, J., Tsubata, T.
  • Journal Title: Science 298 Pages: 2392-2395
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Drosophila myosin phosphatase and its role in dorsal closure. (2002)
  • Author(s): Mizuno, T., Tsutsui, K, Nishida, Y
  • Journal Title: Development 129 Pages: 1215・1223
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characterization of the dCaMKII-GAL4 driver line Whose expression is controlled by the Drosophila Ca2+/calmodulin-Dependent protein kinase II promoter. (2002)
  • Author(s): Takamatsu, Y., et al.
  • Journal Title: Cell Tissue Res. 310 Pages: 237・252
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Oncogenic cell cycle start control. (2001)
  • Author(s): Jinno, S., Lin, J., Yageta, M., Okayama, H.
  • Journal Title: Mutatin Reseach. 477 Pages: 23-29
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. (2001)
  • Author(s): Lin, J., Jinnno, S., Okayama, H.
  • Journal Title: Oncogene 20 Pages: 2000-2009
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism. (2001)
  • Author(s): Tanaka, K., Hao, Z., Kai, M., Okayama, H.
  • Journal Title: EMBO J. 20 Pages: 5779-5790
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Anticancer agent E7070 inhibits amino acid and uracil transport in fission yeast. (2001)
  • Author(s): Tsukahara K, Watanabe T, Hata-Sugi N, Yoshimatsu K, Okayama H, Nagasu T.
  • Journal Title: Mol Pharmacol. 60 Pages: 1254-1259
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Synthesis and Transfection Capability of Multi-Functionalized Fullerene Polyamine. (2001)
  • Author(s): Isobe H, Tomita N, Jinno S, Okayama H, Nakamura E.
  • Journal Title: Chemistry Letters. 30 Pages: 1214-1215
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] PKN delays mitotic timing by inhibition of Cdc25C : Possible involvement of PKN in the regulation of cell division. (2001)
  • Author(s): Misaki, K., Mukai, H., Yoshinaga, C., Oishi, K., Isagawa, T., Takahashi, M., Ohsumi, K., Kishimoto, T., Ono, Y.
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. 98 Pages: 125-129
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Neurofilaments of Klotho, the mutant mouse prematurely displaying symptoms resembling human aging. (2001)
  • Author(s): Uchida, A., Komiya, Y., Tashiro, T., Yorifuji, H., Kishimoto, T., Nabeshima, Y., Hisanaga, S.
  • Journal Title: J. Neurosci. Res. 64 Pages: 364-370
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Inactivation of the checkpoint kinase Cds1 is dependent on cyclin B-Cdc2 kinase activation at the meiotic G2/M-phase transition in Xenopus oocytes. (2001)
  • Author(s): Gotoh, T., Ohsumi, K., Matsui, T., Takisawa, H., Kishimoto, T.
  • Journal Title: J. Cell Sci. 114 Pages: 3397-3406
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identification and analyses of the Xenopus TERT gene that encodes the catalytic subunit of telomerase. (2001)
  • Author(s): Kuramoto, M., Ohsumi, K., Kishimoto, T., Ishikawa, F.
  • Journal Title: Gene 277 Pages: 101-110
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A novel functional domain of Cdc15 kinase is required for its interaction with Tem1 GTPase in Saccharomyces cerevisiae. (2001)
  • Author(s): Asakawa, K., Yoshida, S., Otake, F., Toh-e, A.
  • Journal Title: Genetics 157 Pages: 1437-1450
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Spindle chekpoin in budding yeast. (2001)
  • Author(s): Toh-e, A., Asakawa, K., Yoshida, S.
  • Journal Title: J. Microbiol. 39 Pages: 1-10
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae. (2001)
  • Author(s): Yoshida, S., Toh-e, A.
  • Journal Title: Gene Genet Sys. 76 Pages: 141-147
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A novel factor required for the SUMO1/Smt3 conjugation of yeast septins. (2001)
  • Author(s): Takahashi, Y., Toh-e, A., Kikkuchi, Y.
  • Journal Title: Gene 275 Pages: 223-231
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Yeast Ull1/Siz1 is a novel SUMO-1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates. (2001)
  • Author(s): Takahashi, Y., Kahyo, T., Toh-e, A., Yasuda, H., Kikuchi, Y.
  • Journal Title: J. Biol. Chem. 276 Pages: 48973-48977
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structure and function of cyclin-dependent Pho85 kinase of Saccharomyce cerevisiae. (2001)
  • Author(s): Toh-e, A., Nishizawa, M.
  • Journal Title: J. Gen. Appl. Microbiol. 47 Pages: 107-117
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Nis1 encoded by YNL078W : a new neck protein of Saccharomyces cerevisiae. (2001)
  • Author(s): Iwase, M., Toh-e, A.
  • Journal Title: Gene. Genet. Syst. 76 Pages: 141-147
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Defects in glycosylphosphatidyl inositol(GPI) anchor synthesis activate Hog1 kinase and confer copper-resistance on Saccharomyces cerevisiae. (2001)
  • Author(s): Toh-e, A, Oguchi, T.
  • Journal Title: Gene. Genet. Syst. 76 Pages: 393-410
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] T cell-specific loss of Pten leads to defects in central and peripheral tolerance. (2001)
  • Author(s): Suzuki A, Tsukio-Yamaguchi M, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi P, Koyasu S, Penninger JM, Nakano T, Mak TW.
  • Journal Title: Immunity 14 Pages: 523-534
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] SHP-1 requires inhibitory co-receptors to down-modulate B cell an tigen receptor-mediated phosphorylation of cellular substrates. (2001)
  • Author(s): Adachi T, Wienands J, Wakabayashi C, Yakura H, Reth M, Tsubata T.
  • Journal Title: J. Biol. Chem. 276 Pages: 26648-26655
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular mechanisms for apoptosis induced by signaling through the B cell antigen receptor. (2001)
  • Author(s): Tsubata, T.
  • Journal Title: Int. Rev. Immunol. 20 Pages: 791-803
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A Drosophila MAPKKK, DMEKK1, mediates stress responses through activation of p38 MAPK. (2001)
  • Author(s): Inoue, H. et al.
  • Journal Title: EMBO J. 20 Pages: 5421-5430
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] E2F-dependent transcription of the raf proto-oncogene During Drosophila development. (2001)
  • Author(s): Kwon, E-J., et al.
  • Journal Title: Nucleic Acid. Res. 29 Pages: 1808-1814
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. (2001)
  • Author(s): Lin, J., Jinno, S., Okayama, H.
  • Journal Title: Oncogene 20 Pages: 2000-2009
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism. (2001)
  • Author(s): Tanaka, K., Hao, Z., Kai, M., Okayama, H.
  • Journal Title: EMBOJ. 20 Pages: 5779-5790
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Inactivation of the checkpoint kinase Cdsl is dependent on cyclin B-Cdc2 kinase activation at the meiotic G2/M-phase transition in Xenopus oocytes. (2001)
  • Author(s): Gotoh, T., Ohsumi, K., Matsui, T., Takisawa, H., Kishimoto, T.
  • Journal Title: J. Cell Sci. 114 Pages: 3397-3406
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A novel functional domain of Cdc15 kinase is required for its interaction with Teml GTPase in Saccharomyces cerevisiae. (2001)
  • Author(s): Asakawa, K., Yoshida, S., Otake, F., Toh-e, A.
  • Journal Title: Genetics 157 Pages: 1437-1450
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Spindle Checkpoint Control in Budding Yeast. (2001)
  • Author(s): Toh-e, A., Asakawa, K., Yoshida, S.
  • Journal Title: J. Microbiol. 39 Pages: 1-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Regulation of the localization of Dbf2 and Mobl during cell division of Saccharomyces cerevisiae. (2001)
  • Author(s): Yoshida, S., Toh-e, A.
  • Journal Title: Gene Genet Syst. 76 Pages: 141-147
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A novel factor required for the SUMO1/Smt3 conjugation of yeast septins. (2001)
  • Author(s): Takahashi, Y., Toh-e, A., Kikuchi, Y.
  • Journal Title: Gene 275 Pages: 223-231
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Yeast U111/Sizl is a novel SUMO-1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates. (2001)
  • Author(s): Takahashi, Y., Kahyo, T., Toh-e, A., Yasuda, H., Kikuchi, Y.
  • Journal Title: J. Biol. Chem. 276 Pages: 48973-48977
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structure and function of cyclin-dependent Pho85 kinase of Saccharomyces cerevisiae. (2001)
  • Author(s): Toh-e, A., Nishizawa, M.
  • Journal Title: J. Gen. Appl. Microbiol. 47 Pages: 107-117
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Nisi encoded by YNL078W : a new neck protein of Saccharomyces cerevisiae. (2001)
  • Author(s): Iwase, M., Toh-e, A.
  • Journal Title: Gene. Genet. Syst. 76 Pages: 335-343
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Defects in glycosylphosphatidylinositol(GPI) anchor synthesis activate Hogl kinase and confer copper-resistance on Saccharomyces cerevisiae. (2001)
  • Author(s): Toh-e, A., Oguchi, T.
  • Journal Title: Gene. Genet. Syst. 76 Pages: 393-410
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates. (2001)
  • Author(s): Adachi, T., Wienands, J., Wakabayashi, C, Yakura, H., Reth, M., Tsubata, T.
  • Journal Title: J. Biol. Chem. 276 Pages: 26648-26655
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The polyubiquitin gene is essential for meiosis fission yeast. (2000)
  • Author(s): Okazaki K, Okayama H, Niwa O.
  • Journal Title: Exp Cell Res. 254 Pages: 143-152
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Role of TGF-beta in EGF-induced transformation of NRK cells is sustaining high-level EGF-signaling. (2000)
  • Author(s): Kizaka-Kondoh S, Akiyama N, Okayama H.
  • Journal Title: FEBS Lett. 466 Pages: 160-164
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggest Involvement of Wee1, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr. (2000)
  • Author(s): Masuda M, Nagai Y, Oshima N, Tanaka K, Murakami H, Igarashi H, Okayama H.
  • Journal Title: J Virol. 74 Pages: 2636-2646
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Fission Yeast Esolp Is Required for Establishing Sister Chromatid Cohesion during S Phase. (2000)
  • Author(s): Tanaka, K., Yonekawa, T., Kawasaki, Y., Kai, M., Furuya, K., Iwasaki, M., Murakami, H., Yanagida, M., Okayama, H.
  • Journal Title: Molecular And Cellular Biology 20 Pages: 3459-3469
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A Pcl-like Cyclin Activates the Res2p-Cdc10p Cell Cycle "Start" Transcriptional Factor Complex in Fission Yeast. (2000)
  • Author(s): Tanaka, K., Okayama, H.
  • Journal Title: Molecular Biology of the Cell 11 Pages: 2845-2862
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Loop-mediated isothermal amplification of DNA. (2000)
  • Author(s): Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T.
  • Journal Title: Nucleic Acids Res. 28 Pages: E63
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk-inhibitory kinases. (2000)
  • Author(s): Nakanishi, M., Ando, H., Watanabe, N., Kitamura, K., Ito, K., Okayama, H., Miyamoto, T., Agui, T., Sasaki, M.
  • Journal Title: Genes to Cells. 5 Pages: 839-847
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Fission Yeast Fizzy-related protein srw1p is a G_1-specific promoter of mitotic cyclin B degradation. (2000)
  • Author(s): Yamaguchi, S., Okayama, H., Nurse, P.
  • Journal Title: The EMBO Journal 19 Pages: 3968-3977
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Functionalized Fullerene as an Artificial Vector for Transfection. (2000)
  • Author(s): Nakamura, E., Isobe, H., Tomita, N., Sawamura, M., Jinno, S., Okayama, H.
  • Journal Title: Angew. Chem. Int. Ed. 39 Pages: 4254-4257
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Residual Cdc2 activity remaining at meiosis I exit is essential for meiotic M-M transition in Xenopus oocyte extracts. (2000)
  • Author(s): Iwabuchi M, Ohsumi K, Yamamoto TM, Sawada W, Kishimoto T.
  • Journal Title: EMBO J. 19 Pages: 4513-4523
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A non-proteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M-phase. (2000)
  • Author(s): Nisiyama, A., Tachibana, K., Igarashi, Y, Yasuda, H., Tanahashi, N., Tanaka, K., Ohsumi, K., Kishimoto, T.
  • Journal Title: Genes Dev. 14 Pages: 2344-2357
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] c-Mos forces the mitotic cell cycle to undergo meiosis II to produce haploid gametes. (2000)
  • Author(s): Tachibana, K., Tanaka, D., Isobe, T., Kishimoto, T.
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. 97 Pages: 14301-14306
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization. (2000)
  • Author(s): Kitazawa H, Iida J, Uchida A, Haino-Fukushima K, Itoh TJ, Hotani H, Ookata K, Murofushi H, Bulinski JC, Kishimoto T, Hisanaga S.
  • Journal Title: Cell Struc. Funct. 25 Pages: 33-39
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Brain-derived neurotrophic factor-induced phosphorylation of neurofilament-H subunit in primary culture of embryo rat cortical neurons. (2000)
  • Author(s): Tokuoka H, Saito T, Yorifuji H, Wei F-Y, Kishimoto T, Hisanaga S.
  • Journal Title: J. Cell Sci. 113 Pages: 1059-1068
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. (2000)
  • Author(s): Kusakawa G, Saito T, Onuki R, Ishiguro K, Kishimoto T, Hisanaga S.
  • Journal Title: J. Biol. Chem. 275 Pages: 17166-17172
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes. (2000)
  • Author(s): Kawahara H, Kasahara M, Nishiyama A, Ohsumi K, Goto T, Kishimoto T, Saeki Y, Yokosawa H, Shimbara N, Murata S, Chiba T, Suzuki K, Tanaka T.
  • Journal Title: EMBO J. 19 Pages: 4144-4153
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Regulation of JNK by Src during Drosophila development. (2000)
  • Author(s): Tateno, M., Nishida, Y., Adachi-Yamada, T.
  • Journal Title: Science 287 Pages: 324-327
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A Drosophila Winged-helix nude (Whn)-like transcription factor with essential functions throughout development. (2000)
  • Author(s): Sugimura, I., Adachi-Yamada, T., Nishi, Y., Nishida, Y.
  • Journal Title: Develp. Growth Differ. 42 Pages: 237-248
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response. (2000)
  • Author(s): Kwon E-J, Park H-S, Kim Y-S, Oh E-J, Nishida Y, Matsukage A, Yoo M-A, Yamaguchi M.
  • Journal Title: J. Biol. Chem. 275 Pages: 19824-19830
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Characterization of a Drosophila homologue of the human myelodysplasia/myeloid leukemia factor (MLF). (2000)
  • Author(s): Ohno K, Takahashi Y, Hirose F, Inoue YH, Taguchi O, Nishida Y, Matsukage A, Yamaguchi M.
  • Journal Title: Gene 260 Pages: 133-143
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] The polyubiquitin gene is essential for meiosis in fission yeast. (2000)
  • Author(s): Okazaki K, Okayama H, Niwa O.
  • Journal Title: Exp Cell Res. 254 Pages: 143-152
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggest Involvement of Weel, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr. (2000)
  • Author(s): Masuda M, Nagai Y, Oshima N, Tanaka K, Murakami H, Igarashi H, Okayama H.
  • Journal Title: J Virol. 74 Pages: 2636-2646
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A Pcl-like Cyclin Activates the Res2p-CdclOp Cell Cycle "Start" Transcriptional Factor Complex in Fission Yeast. (2000)
  • Author(s): Tanaka, K., Okayama, H.
  • Journal Title: Molecular Biology of the Cell 11 Pages: 2845-2862
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Identification and characterization of human Wee1B, a new member of the Weel family of Cdk-inhibitory kinases. (2000)
  • Author(s): Nakanishi, M., Ando, H., Watanabe, N., Kitamura, K., Ito, K., Okayama, H., Miyamoto, T., Agui, T., Sasaki, M.
  • Journal Title: Genes to Cells. 5 Pages: 839-847
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Fission Yeast Fizzy-related protein srwlp is a Gl-specific promoter of mitotic cyclin B degradation. (2000)
  • Author(s): Yamaguchi, S., Okayama, H., Nurse, P.
  • Journal Title: The EMBO Journal 19 Pages: 3968-3977
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Residual Cdc2 activity remaining at meiosis I exit is essential for meiotic M-M transition in Xenopus oocyte extracts. (2000)
  • Author(s): Iwabuchi, M., Ohsumi, K., Yamamoto, T.M., Sawada, W., Kishimoto, T.
  • Journal Title: EMBOJ. 19 Pages: 4513-4523
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A non-proteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M-phase. (2000)
  • Author(s): Nishiyama, A., Tachibana, K., Igarashi, Y., Yasuda, H., Tanahashi, N., Tanaka, K., Ohsumi, K., Kishimoto, T.
  • Journal Title: Genes Dev. 14 Pages: 2344-2357
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization. (2000)
  • Author(s): Kitazawa H, Iida J, Uchida A, Haino-Fukushima K, Itoh TJ, Hotani H, Ookata K, Murofushi H, Bulinski J.C., Kishimoto T, Hisanaga S.
  • Journal Title: Cell Struc. Funct. 25 Pages: 33-39
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Brain-derived neurotrophic factor-induced phosphorylation of neurofilament-H subunit in primary culture of embryo rat cortical neurons. (2000)
  • Author(s): Tokuoka, H., Saito, T., Yorifuji, H., Wei, F-Y., Kishimoto, T., Hisanaga, S.
  • Journal Title: J. Cell Sci. 113 Pages: 1059-1068
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. (2000)
  • Author(s): Kusakawa, G., Saito, T., Onuki, R., Ishiguro, K., Kishimoto, T., Hisanaga, S.
  • Journal Title: J. Biol. Chem. 275 Pages: 17166-17172
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes. (2000)
  • Author(s): Kawahara, H., Kasahara, M., Nishiyama, A., Ohsumi, K., Goto, T., Kishimoto, T., Saeki, Y., Yokosawa, H., Shimbara, N., Murata, S., Chiba, T., Suzuki, K., Tanaka, T.
  • Journal Title: EMBO J. 19 Pages: 4144-4153
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] 細胞周期集中マスター(北川雅敏編) (2006)
  • Author(s): 岸本健雄(分担)
  • Total Pages: 154
  • Publisher: 羊土社
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 発生における細胞増殖制御 (2004)
  • Author(s): 竹内隆, 岸本健雄(編集)
  • Total Pages: 198
  • Publisher: シュプリンガーフェアラーク東京
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 日本生化学会・バイオサイエンスの新世紀 第6巻 「細胞の誕生と死」(長田重一, 山本雅編) (2001)
  • Author(s): 岸本健雄(分担)
  • Total Pages: 198
  • Publisher: 共立出版
  • Description: 「研究成果報告書概要(和文)」より