Dynamics of Developmental Systems

2005 Fiscal Year Final Research Report Summary

• Project/Area Number: 12061101
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: National Institute for Basic Biology (2004-2006); Okazaki National Research Institutes (2000-2003)
• Principal Investigator: UENO Naoto National Institute for Basic Biology, Laboratory of Morphogenesis, Professor, 形態形成研究部門, 教授 (40221105)
• Project Period (FY): 2004 – 2008
• Keywords: early development / embryonic induction / cell-to-cell interation / microarray / organogenesis / evolution / morphology / gene network

Research Abstract

The first aim of this SOKATSU-HAN is to promote academic interaction and exchange of technology among the members of this priority area. In order to do so, we core-members of SOKASRU-HAN have arranged annual assembly meetings so that every member can have sufficient time to discuss with others between each presentation. During the meeting, we also tried to a time for intermingling of members from slightly different fields. We also stressed to encourage young people to join discussions. These were successfully achieved by the appropriate selection of the meeting sites and planning of the programs.
Secondly, we aimed to familiarize our activities to the public. Some members paid substantial efforts to write books and review articles so that not only for the people in science but also for general public can understand the importance of the research in this area. To attract people to biology, we also organized a lecture series by inviting a famous biology textbook authos Scott Gilbert and an insect photographer Kazuo Unno to the public including high school students and teachers, which was very successful.
Because of these planning and activities of SOKATSU-HAN, we could promote the priority area "Dynamics of Developmental Systems" so efficiently.

Research Products

• [Journal Article] FGF signal regulates gastrulation cell movements and morphology through its target NRH. (2005)
  • Author(s): Chung, H.A., Hyodo-Miura, J., Nagamune, T., Ueno, N.
  • Journal Title: Dev. Biol. 282 Pages: 95-110
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development. (2005)
  • Author(s): Matsuda, Y., Wakamatsu, Y., Kohyama, J., Okano, H., Fukuda, K., Yasugi, S.
  • Journal Title: Development 132 Pages: 2783-2793
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] caudal is required for gnathal and thoracic patterning and for posterior elongation in the intermediate-germband cricket Gryllus bimaculatus. (2005)
  • Author(s): Shinmyo, Y., Mito, T., Matsushita, T., Sarashina, I., Miyawaki, K., Ohuchi, H., Noji, S.
  • Journal Title: Mech. Dev. 122 Pages: 231-239
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Non-canonical functions of hunchback in segment patterning of the intermediate germ cricket Gryllus bimaculatus. (2005)
  • Author(s): Mito T, Sarashina I, Zhang H, Iwahashi A, Okamoto H, Miyawaki K, Shinmyo Y, Ohuchi H, Noji, S.
  • Journal Title: Development 132 Pages: 2069-2079
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development. (2005)
  • Author(s): Matsuda, Y., Wakamatsu, Y., Kohyama, J., Okano, H., Fukuda, K., *Yasugi, S.
  • Journal Title: Development 132 Pages: 2783-2793
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] caudal is required for gnathalandthoracicpatterning and for posterior elongation in the intermediate-germband cricket Gryllus bimaculatus. (2005)
  • Author(s): Shinmyo, Y., Mito, T., Matsushita, T., Sarashina, I., Miyawaki, K., Ohuchi, H., *Noji, S.
  • Journal Title: Mech. Dev. 122 Pages: 231-239
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Non-canonical functions of hunchback in segment patterning of the intermediate germ cricket Gryllus bimaculatus. (2005)
  • Author(s): Mito T, Sarashina I, Zhang H, Iwahashi A, Okamoto H, Miyawaki K, Shinmyo Y, Ohuchi H, *Noji, S.
  • Journal Title: Development 132 Pages: 2069-2079
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Screening of FGF target genes in Xenopus by microarray : temporal dissection of the signalling pathway using a chemical inhibitor. (2004)
  • Author(s): Chung, H.A., Hyodo-Miura, J., Kitayama, A., Terasaka, C., Nagamune, T., Ueno, N.
  • Journal Title: Genes Cells 9 Pages: 749-761
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular analysis of the determination of developmental fate in the small intestinal epithelium in the chicken embryo (2004)
  • Author(s): Hiramatsu, H., Yasugi, S.
  • Journal Title: Int. J. Dev. Biol. 48 Pages: 1141-1148
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Screening of FGF target genes in Xenopus by microarray : temporal dissection of the signalling pathway using a chemical inhibitor. (2004)
  • Author(s): Chung, H.A., Hyodo-Miura, J., Kitayama, A., Terasaka, C., Nagamune, T., *Ueno, N.
  • Journal Title: Genes Cells 9 Pages: 749-761
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular analysis of the determination of developmental fate in the small intestinal epithelium in the chicken embryo. (2004)
  • Author(s): Hiramatsu, H., *Yasugi, S.
  • Journal Title: Int. J. Dev. Biol. 48 Pages: 1141-1148
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. (2003)
  • Author(s): Ohkawara, B., Yamamoto, T., Tada, M., Ueno, N.
  • Journal Title: Development 130 Pages: 2129-2138
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. (2003)
  • Author(s): Ohkawara, B., Yamamoto, T., Tada, M., *Ueno, N.
  • Journal Title: Development 130 Pages: 2129-2138
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Action range of BMP is defined by its N-terminal basic amino acid core. (2002)
  • Author(s): Ohkawara, B., Iemura, S.-I., ten Dijke, P., Ueno, N.
  • Journal Title: Curr. Biol. 12 Pages: 1-20
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A C. elegans TGF-β, DBL-1, controls the expression of LON-1 that regulates polyploidization and body length. (2002)
  • Author(s): Morita, K., Flemming, A., Sugihara, Y., Mochii, M., Suzuki, Y., Yoshida, S., Wood, B., Kohara, Y., Leroi, A.M., Ueno N.
  • Journal Title: EMBO J. 21 Pages: 1063-1073
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Involvment of the signal transduction pathway mediated by epidermal growth factor receptor in the differentiation of chicken glandular stomach. (2002)
  • Author(s): Takeda, J., Tabata, H., Fukuda, K., Yasugi, S.
  • Journal Title: Dev. Growth ＆ Differ 44 Pages: 501-508
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] The pre-gut endoderm of chick embryo is reginolized by 1.5 days of development. (2002)
  • Author(s): Matsushita, S., Ishii, Y., Scotting, P.J., Kuroiwa, A., Yasugi, S.
  • Journal Title: Dev. Dyn. 223 Pages: 33-47
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Correlation of expression patterns of homothorax, dachshund, and Distal-less with the proximodistal segmentation of cricket leg bud. (2002)
  • Author(s): Inoue, Y., Mito, T., Miyawaki, K., Matsushima, K., Shinmyo, Y., Heanue, T.A., Mardon, G., Ohuchi, H., Noji, S.
  • Journal Title: Mech. Dev. 113 Pages: 141-148
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Involvement of hedgehog, wingless, and dpp in the initiation of proximodistal axis formation during the regeneration of insect legs, a verification of the modified boundary model. (2002)
  • Author(s): Mito, T., Inoue, Y., Kimura, S., Miyawaki, K., Niwa, N., Shinmyo, Y., Ohuchi, H., Noji, S.
  • Journal Title: Mech. Dev. 114 Pages: 27-35
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Action range of BMP is defined by its N-terminal basic amino acid core. (2002)
  • Author(s): Ohkawara, B., Iemura, S.-L, ten Dijke, P., *Ueno.N.
  • Journal Title: Curr. Biol. 12 Pages: 1-20
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] elegans TGF-b, DBL-1, controls the expression of LON-1 that regulates polyploidization and body length. (2002)
  • Author(s): Morita, K., Flemming, A., Sugihara, Y., Mochii, M., Suzuki, Y.Yoshida, S., Wood, B., Kohara, Y., Leroi, A.M., *Ueno N.A C.
  • Journal Title: EMBO J. 21 Pages: 1063-1073
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Involvment of the signal transduction pathway mediated by epidermal growth factor receptor in the differentiation of chicken glandular stomach. (2002)
  • Author(s): Takeda, J., Tabata, H., Fukuda, K., *Yasugi, S.
  • Journal Title: Dev. Growth ＆ Differ. 44 Pages: 501- 508
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The pre-gut endoderm of chick embryo is reginolized by 1.5 days of development. (2002)
  • Author(s): Matsushita, S., Ishii, Y., Scotting, P.J., Kuroiwa, A., *Yasugi, S.
  • Journal Title: Dev. Dyn. 223 Pages: 33-47
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Correlation of expression patterns of homothorax, dachshund, and Distal-less with the proximodistal segmentation of cricket leg bud. Mech. Dev.113, 141-148, 2002 (2002)
  • Author(s): Inoue, Y., Mito, T., Miyawaki, K., Matsushima, K., Shinmyo, Y., Heanue, T.A., Mardon, G., Ohuchi, H., *Noji, S.
  • Journal Title: Mech. Dev. 113 Pages: 141-148
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Involvement of hedgehog, wingless, and dpp in the initiation of proximodistal axis formation during the regeneration of insect legs, a verification of the modified boundary model. (2002)
  • Author(s): Mito, T., Inoue, Y., Kimura, S., Miyawaki, K., Niwa, N., Shinmyo, Y., Ohuchi, H., *Noji, S.
  • Journal Title: Mech. Dev. 114 Pages: 27-35
  • Description: 「研究成果報告書概要(欧文)」より