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2003 Fiscal Year Final Research Report Summary

DEVELOPMENT OF TREATMENT WITH RESPECT TO IDIOPATHIC SCOLIOSIS

Research Project

Project/Area Number 12450047
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionNAGOYA UNIVERSITY (2003)
Toyohashi University of Technology (2000-2002)

Principal Investigator

AZEGAMI Hideyuki  NAGOYA UNIVERSITY, GRADUATE SCHOOL OF INFORMATION SCIENCE, PROFESSOR, 大学院・情報科学研究科, 教授 (70175876)

Project Period (FY) 2000 – 2003
KeywordsSCOLIOSIS / FINITE ELEMENT METHOD / BUCKLING / GROWTH / MECHANICAL SPINE MODEL / BIOMECHANICS
Research Abstract

Objectives of the present research were as follows.
1. To confirm a buckling hypothesis for idiopathic scoliosis that is buckling phenomena induced by growth of vertebral bodies
2. Based on the buckling hypothesis, to identify optimum reinforcement parts to prevent the buckling phenomena
3. To make it possible to analyze etiology for individuals of patients and to indicate the optimum treatments for them Results were as follows.
1. A spinal finite element model with thoracic cage was constructed using 68,582 elements and 84,603 nodes. Material properties of disks and joints were identified by comparing with the experimental results by literatures. From the results of the first to the seventh or eighth buckling modes for 49 cases changing growth parts, it was shown that the fourth and the sixth buckling modes are mechanical etiology for clinical shapes of single and double curves respectively. On the other hand, to observe these buckling phenomena by experiment, mechanical spine models were … More constructed using data of the numerical model. With these models, the change in the second natural vibration eigenvalue was measured by experimental modal analysis. The obtained result showing a decrease in the second natural vibration eigenvalue with the growth of vertebral bodies is confirms of the buckling hypothesis.
2. Shape gradient density, sensitivity in another word, with respect to maximization problem of the critical growth of vertebral bodies to the fourth and sixth buckling modes was analyzed by the finite element method. Based on the numerical results, possibility to identify optimum reinforcement parts to prevent the buckling phenomena of various modes was demonstrated.
3. To deform the spinal finite element model to fit individuals of patients, a numerical method was developed using formulation of morphing problem of finite element models to three dimensional voxel model constructed from CT or MRI images. Applying the method to fitting two dimensional finite element models to CT images and the spinal finite element model to standing X-ray image of idiopathic scoliosis, applicability to individuals of patients was demonstrated. However, etiology analysis for individuals of patients was left in the future work. Less

  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] 畔上秀幸: "座屈に対する形状最適化"日本機械学会論文集A編. 66. 1262-1267 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 竹内謙善: "特発性側彎症に対する感度解析(構造最適化理論の応用)"脊柱変形,日本側轡症学会誌. 15. 24-27 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 後藤学: "特発性側彎症発生における座屈と骨リモデリングの関与(有限要素法を用いた検討)"脊柱変形,日本側彎症学会誌. 15. 28-31 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 畔上秀幸: "構造最適化理論の医療への応用"日本機械学会講習会「構造解析技術とモデル化技術の最前線」教材. 00-84. 67-76 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kenzen Takeuchi: "Study on Treatment with Respect to Idiopathic Scoliosis (Sensitivity Analysis Based on Buckling Theory)"JSME International Journal Series C. 44. 1059-1064 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 竹内謙善: "特発性側彎症の成因に関する数値シミュレーション(多様なモードの成因)"脊柱変形,日本側彎症学会誌. 16. 11-16 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 竹内謙善: "特発性側彎症の成因に関する計算力学研究(重力に抗する骨構築に起因した座屈説)"日本計算工学会論文集. 4. 153-160 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hideyuki Azegami: "Modeling Skeletal Shape Changes and Growth in Scoliosis"Proceedings of the Fourth World Congress of Biomechanics. (CD-ROM). (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 笹岡 竜: "特発性側彎症の成因に関する力学模型実験(精密な脊柱力学模型を用いた検討)"脊柱変形,日本側彎症学会誌. 17. 18-22 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Manabu Goto: "Buckling and bone modeling as factors in the development of idiopathic scoliosis."Spine. 28. 364-370 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ryu Sasaoka: "Investigation of buckling phenomenon induced by growth of vertebral bodies using a mechanical spine model"JSME International Journal Series C. 46. 1382-1387 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hideyuki Azegami, Yasuhiro Sugai, Masatoshi Shimoda: "Shape Optimization for Buckling (in Japanese)"Transactions of the JSME Series A. 66. 1262-1267 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kenzen Takeuchi, Hideyuki Azegami, Shunji Murachi, Junzoh Kitoh, Yoshito Ishida, Noriaki Kawakami, Mitsunori Makino: "Sensitivity Analysis with Respect to Idiopathic Scoliosis Application of Structural Optimization Theory (in Japanese)"Spinal Deformity, The Journal of Japanese Scoliosis Society. 15. 24-27 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Manabu Goto, Noriaki Kawakami, Yuji Matsubara, Tokumi Kanemura, Hideyuki Azegami, Kenzen Takeuchi, Ryu Sasaoka, Yukihiro Matsuyama: "Investigation of the Etiology of Idiopathic Scoliosis Using Finite Element Method (in Japanese)"Spinal Deformity, The Journal of Japanese Scoliosis Society. 15. 28-31 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hideyuki Azegami: "Application of Structural Optimization Theory to Medical Treatment (in Japanese)"Textbook of JSME Seminer. No.00-84. 67-76 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kenzen Takeuchi: "Study on Treatment with Respect to Idiopathic Scoliosis (Sensitivity Analysis Based on Buckling Theory)"JSME International Journal Series C. 44. 1059-1064 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kenzen Takeuchi, Hideyuki Azegami, Ryu Sasaoka, Shunji Murachi, Junzoh Kitoh, Yoshito Ishida, Noriaki Kawakami, Manabu Goto, Mitsunori Makino, Yukihiro Matsuyama: "Numerical Simulation on Etiology of Idiopathic Scoliosis Modal Investigation (in Japanese)"Spinal Deformity, The Journal of Japanese Scoliosis Society. 16. 11-16 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kenzen Takeuchi, Hideyuki Azegami, Shunji Murachi, Junzoh Kitoh, Yoshito Ishida, Noriaki Kawakami, Mitsunori Makino: "Computational Study on the Etiology of Idiopathic Scoliosis Buckling Hypothesis Induced by Bone Modeling against Gravity (in Japanese)"Transactions of JSCES (Japan Society for Computational Engineering and Science). 4. 153-160 (2002)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2005-04-19  

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