The bone remodeling of maxillo-facial structure following orthodontic force

2002 Fiscal Year Final Research Report Summary

• Project/Area Number: 12470463
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 矯正・小児・社会系歯学
• Research Institution: Nagasaki University
• Principal Investigator: CHIKUBA Satoshi Nagasaki University, Dept. of Orthodontics, Ass. Prof., 歯学部附属病院, 助手 (50244075)
• Co-Investigator(Kenkyū-buntansha): KIMURA Mitsutaka Kyushu Dental College, Professor, 教授 (70047801)
• Project Period (FY): 2000 – 2002
• Keywords: Remodeling / stress analysis / finite element method

Research Abstract

The purpose of this study was to clarify the relationship between the bone remodeling of maxillo-facial structure and orhodontic force. The Winter rats, 20 weeks old were fed a normal diet. These rats were divided into three groups-by the period of application of orthodontic force. The rats were maintained for 8 weeks prior to sacrifice. 72 hours prior to sacrifice, orthodontic elastics were inserted between the crowns of upper right first and second molars of each rat using the technique described by Waldo.
To investigate bone dynamic histomorphometry, labels of oxytetracycline (TC) and (CL) were performed. TC was infected 9 and 8 days prior to sacrifice and CL was injected 4 days later. The results were as follows: 1. Exp. group produced a significant decrease in cancellous bone mass and adjusted mineral apposition rate (Aj-AR). 2. Eroded surface per alyeolar bone surface in exp. groups was increased with increasing period of application. 3. Alveolar bone dynamics induced by the mechanical stress was accelated by the periods.