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2001 Fiscal Year Final Research Report Summary

Simultanous Measurement of Velocity Signals at Multiple Points in the Heart Wall for Noninvasive Evaluation of Left Ventricular Inner Pressure and Elastic Modulus

Research Project

Project/Area Number 12650416
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Measurement engineering
Research InstitutionTOHOKU UNIVERSITY

Principal Investigator

KANAI Hiroshi  Tohoku University, Graduate School of Engineering, Professor, 大学院・工学研究科, 教授 (10185895)

Co-Investigator(Kenkyū-buntansha) KOIWA Yoshiro  Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 (80091685)
Project Period (FY) 2000 – 2001
Keywordsheart diseases / Medical ultrasonics / eigenvibration / phased tracking method / noninvasive measurement / tissue characterization / left ventricular inner pressure / vibration measurement
Research Abstract

Myocardial motion exhibits frequency components of up to 100 Hertz as found by a phased tracking method. To simultaneously measure the rapid and minute velocity signals at multiple points along the surface of the left ventricle (LV), in this study, conventional ultrasonic diagnosis equipment was modified to allow 10 scan lines from a sector scanner to be arbitrarily selected in real time for analysis. By considering the maximum value of the velocity in the heart wall and the maximum depth from the chest surface, the number of transmission directions of the ultrasonic pulses should be carefully confirmed to be 10 to avoid aliasing, which is much less than the number employed in conventional tissue Doppler imaging (TDI). By applying the system, the velocity signals at about 240 points in the heart walls were simultaneously measured for three healthy volunteers. During a short period of 35 ms around end-diastole, the velocity signals varied spatially in the heart wall. At the end of systo … More le, in the wavelets near the base of the interventricular septum (IVS), the slow pulse continued for about 30 ms just before the radiation timing of the second heart sound. Then, a steep pulse occurred just at the timing of the closure of the aortic valve. The steep pulse at the base preceded that at the apex by several milliseconds. By Fourier transforming each wavelet, the spatial distribution of the phase of the steep pulsive components were clearly displayed. By applying the measurement method to two patients with aortic stenosis (AS) , irregular vibration signals, which correspond to the murmur of the heart sound, could be directly detected during ejection period. In conventional TDI, only the large slow movements due to the heartbeat are displayed, while these rapid and minute velocity components cannot be displayed. In this study, moreover, the phase components were detected for the first time from each of the velocity signals simultaneously measured at multiple points along the 10 scan lines. This measurement and method of analysis offer potential for new diagnostic techniques in cardiac dysfunction. Less

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] H.Kanai, S.Yonechi, I.Susukida, Y.Koiwa 他2名: "Onset of Pulsatile Waves in the Heart Walls at End-systole"Ultrasonics. 38. 405-411 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Kanai, Y.Koiwa: "Real-time Velocimetry for Evaluation of Change in Thickness of Arterial Wall"Ultrasonics. 38. 381-386 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 長谷川, 金井, 星宮, 小岩: "不均一な壁厚を有する管の局所壁弾性率の計測法"超音波医学. 28. J3-J13 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Kanai, Y.Koiwa: "Myocardial Rapid Velocity Distribution"Ultrasound in Medicine and Biology. 27. 481-498 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Watanabe, H.Kanai: "Optimization of Focal Position of Ultrasonic Beam in Measurement of Small Change in Thickness of Arterial Wall"Japanese Journal of Applied Physics. 40. 3918-3921 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Mita, H.Kanai, Y.Koiwa 他2名: "Cross-sectional Elastic Imaging of Arterial Wall using Intravascular Ultrasonography (IVUS)"Japanese Journal of Applied Physics. 40. 4753-4762 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 金井 浩, 他70名: "『臨床検査』臨時増刊号『超音波検査の技術と臨床』"医学書院. 335 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hiroshi Kanai, Sachiko Yonechi, Ikuko Susukida, Yoshiro Koiwa, Hide-ichi Kamada, Motonao Tanaka: ""Onset of Pulsatile Waves in the Heart Walls at End-systole,""Ultrasonics. vol. 38, No. 1. 405-411 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiroshi Kanai, Yoshiro Koiwa: ""Real-time Velocimetry for Evaluation of Change in Thickness of Arterial Wall,""Ultrasonics. vol. 38, No. 1. 381-386 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hideyuki Hasegawa, Hiroshi Kanai, Nozomu Hoshimiya, Yoshiro Koiwa: ""Evaluation of Regional Elastic Modulus of Cylindrical Shell with Nonuniform Wall Thickness,""Journal of Medical Ultrasonics. vol. 28, No. 1. J3-J13 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiroshi Kanai, Yoshiro Koiwa: ""Myocardial Rapid Velocity Distribution,""Ultrasound in Medicine and Biology. vol. 27, No. 4. 481-498 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaru Watanabe, Hiroshi Kanai: ""Optimization of Focal Position of Ultrasonic Beam in Measurement of Small Change in Arterial Wall Thickness,""Japanese Journal of Applied Physics. Vol. 40, Part1, No. 5B. 3918-3921

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hitoshi Mita, Hiroshi Kanai, Yoshiro Koiwa, Masataka Ichiki, Fumiaki Tezuka: ""Cross-sectional Elastic Imaging of Arterial Wall using Intravascular Ultrasonography (IVUS),""Japanese Journal of Applied Physics. Vol. 40, Part1, No. 7. 4753-4762 (2001)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2003-09-17  

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