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2002 Fiscal Year Final Research Report Summary

Physiological functions of polyunsaturated fatty acids and nutritional recommendation of the essential lipids for infants and toddlers

Research Project

Project/Area Number 12670777
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pediatrics
Research InstitutionTeikyo University School of Medicine

Principal Investigator

SHIMASAKI Hiroyuki  Teikyo Univ, Asso.Professor, 医学部, 助教授 (20112758)

Project Period (FY) 2000 – 2002
KeywordsEssential fatty acid / polyunsaturated fatty acid / Brain lipid / Cholesterol / Infant formulas
Research Abstract

Fatty acids have a variety of physiological functions such as energy supply, neural transmission, membrane structure, a precursor of biological active substances and etc. Long-chain polyunsaturated fatty acids (LCPUFA) which is essential for human development, is supplied to fetus and infants through cord blood and breast milk or/and infant formula, respectively, however, the mechanism still remains to be dissolved. We analyzed fatty acids from these materials and phospholipids from colostrum, comparing with that of infant formulas (IF) in Japan and recommended that PUFA should be added to the present infant formulas in Japan to produce better nutrition for infants and toddlers.

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] S.Hanaka, et al.: "Gene expression related to cholesterol metabolism in mouse brain during development"Brain & Development. 22. 321-326 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] L.Wang, et al.: "Comparison of the fatty acid composition of total lipids and phospholipids in breast milk from Japanese women"Pediatrics International. 42. 14-20 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Shimizu, et al.: "Dietary Fish Oil for Hens Affects the Fatty Acid Composition of Egg Yolk Phospholipids and Gives a Valuable Food with an Ideal Balance of n-6 and n-3 Essential Fatty Acids for Human Nutrition"J.Oleo Science. 50. 797-803 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Shimasaki, et al.: "Dietary effect of docosahexaenoic acid-rich eggs on serum lipids in Real-"J.Oleo Science. 52. 109-119 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Hanaka: "Developmental regulation of cholesterol metabolism in the brain"帝京医学雑誌. 24. 41-55 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Kaneko: "Long chain polyunsaturated fatty acids in cord blood and colostrum-"帝京医学雑誌. 24. 107-118 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S. Hanaka, T. Abe, H. Itakura, A. Matsumoto: "Gene expression related to cholesterol metabolism in mouse brain during development"Brain & Development. 22. 321-326 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] L. Wang, Y. Shimizu, S. Kaneko, S. Hanaka, T. Abe,H. Shimasaki, H. Hisaki, H. Nakajima: "Comparison of the fatty acid composition of total lipids and phospholipids in breast milk from Japanese women"Pediatrics International. 42. 14-20 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y. Shimizu, K. Arai, S. Ise, H. Shimasaki: "Dietary fish oil for hens affects the fatty acid composition of egg yolk phospholipids and gives a valuable food with an ideal balance of n-6 and n-3 essential fatty acids for human nutrition"J. Oleo Science,. 50. 797-803 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H. Shimasaki, E. Yamashita, Y. Shimizu, S. Ise: "Dietary effect of docosahexaenoic acid-rich eggs on serum lipids in healthy human subjects: A randomized double-blind controlled study"J. Oleo Science,. 52. 109-119. (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Hanaka: "Developmental regulation of cholesterol metabolism in the brain"Teikyo Medical Journal. 24. 41-55. (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Kaneko: "Long chain polyunsaturated fatty acids in cord blood and colostrum compared with maternal blood and infant formulas"Teikyo Medical Journal. 24. 107-118. (2001)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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