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2002 Fiscal Year Final Research Report Summary

Establishment of bioartificial pancreas using pancreatic stem all for severe diabetes mellitus

Research Project

Project/Area Number 12671153
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionNIPPON MEDICAL SCHOOL (2002)
Kyoto University (2000-2001)

Principal Investigator

MIYAMOTO Masaaki  Nippon Medical School, First Dept. of Internal Medical, Associate Professor, 医学部, 助教授 (50229895)

Project Period (FY) 2000 – 2002
Keywordsislets / isolation procedure / cry a preservation of islets / islet transplantation / two-step isolation procedure of islets / islets
Research Abstract

(1) Development of isolation procedure of pancreatic islets for large animals. We developed 2-step automated isolation procedure of pancreatic islets for miniature swine and dogs.
This procedure is possible to use human pancreatic islets for human islets transplantation.
(2) Development of automated cry a preservation procedure for pancreatic islets. We developed cry a preservation procedure employing a freezer bag for pancreatic islets using a newly developed cry a protectant.

  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] 宮本正章: "重症難治性糖尿病壊疽に対する自己骨髄幹細胞浸透人工真皮を用いた血管再生治療"Complication8/1特集"糖尿病と足". (印刷中).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masaaki Miyamoto et al.: "Development of a cryopreservation procedure employing a freezer bag for pancreatic islets using a newly developed cryoprotectant"Cell Transplantation. 10. 363-371 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masaaki Miyamoto et al.: "Current progress and perspectives in cell therapy for diabete mellitus"Human Cell. 14(4). 293-300 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masaaki Miyamoto: "Establishment of fluorescein diacetate and ethidium bromide assay for isolation Islets"Cell Transplantation. 9. 681-686 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Miyamoto Masaaki et al.: "Improuent of modified two layer preservation method in islet isolation"Transplant Proc.. 32. 1660-1661 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masaaki Miyamoto: "Therapeutic angiogenessi of autologus bone-morrow stem all arid Endothelial progenitor-cells (EPCs)-impregnated artificial dermis for refractory severe diabetes gangrenes"Complication. in press.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaaki Miyamoto, et al.: "Development of cry a preservation procedure employing a freezer bag for pancreatic istets using a newly developed cry a protectant"Cell Transplantation. 10. 363-371 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaaki Miyamoto et al.: "Current progress and perspectives in all therapy for diabetes Mellitus"Humann cell. 144. 293-300 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaaki Miyamoto, et al.: "Development of Fluoresce in Diabetate and Ethiduim Bromide Assay for islets"Cell Transplantation. 9. 681-686 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaaki Miyamoto, et al.: "Improvement of modified two layer preservation in islets isolation"Transplant Proc.. 32. 1660-1661 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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