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2002 Fiscal Year Final Research Report Summary

Establishment of education system based on the regional health promotion activity to prevent life style-related diseases in children

Research Project

Project/Area Number 12672268
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 基礎・地域看護学
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

OHZEKI Takehiko  Hamamatsu University, Faculty of Medicine, Professor, 医学部, 教授 (20152126)

Co-Investigator(Kenkyū-buntansha) 安梅 勅江  浜松医科大学, 医学部, 教授 (20201907)
ARAKIDA Mikako  Hamamatsu University, Faculty of Medicine, Professor, 医学部, 教授 (50303558)
KANAMORI Masao  Hamamatsu University, Faculty of Medicine, Associate Professor, 医学部, 助教授 (90127019)
Project Period (FY) 2000 – 2002
KeywordsLife style-related disorder / Life style / Regional health promotion / Health education / Health education system / Elementary school pupil / Junior high school pupil / Leptin
Research Abstract

The purpose of the study was to establish a school-based system for health promotion in childrdn. Boys and girls in elementary schools (1177) and junior high schools (1064) joined the study. The following items were assessed: (1) body height and weight, and body composition, (2) biochemical and hormonal markers, (3) life style-related factors such as foods and exercise, etc. For assessment of obesity, percentage of overweight for the standard was shown more reliable than BMI (body mass index) especially in childhood. There were significant regional differences in serum lipid levels, suggesting that in addition to genetic causes intervention and education seemed effective to improve dyslipidemia in children. Fat-derived hormone, leptin, was significantly related with body weight and the degree of overweight. Leptin was demonstrated as one of the indicators for fatness even in children. There were gender differences in eating behavior and favorite foods already in childhood. Follow-up study demonstrated efficacy of the health promotion activity in the study. The school-based system for prevention of life style-related diseases is suggested effective for boys and girls in the elementary schoolas well as junior high school.

  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] Liu YJ, Nakagawa Y, Toya K, Wang Y, Saegusa H, Nakanishi T, Ohzeki T: "Effects of spironolactone on systolic blood pressure in experimental diabetic rats"Kidney International. 57. 2064-2071 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakanishi T, Li R, Liu Z, Yi M, Nakagawa Y, Ohzeki T: "Sexual dimorphism in relationship of serum leptin and relative weight for the standard in normal-weight, but not in overweight children as well as adolescents"European Journal of Clinical Nutrition. 55. 989-993 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Endoh A, Inoue N, Katoh T, Nakamura T, Sugimura H, Ohzeki: "A case of glycogen storage disease IA with multiple hepatic tumors managed by transcatheter arterial embolization and acarbose diet"Journal of Pediatric Gastroenterology and Nutrition. 33. 333-336 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Liu Y, Nakagawa Y, Wang Y, Li R, Li X, Ohzeki T, Friedman T: "Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice"Diabetes. 52. 1409-1416 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Fujisawa Y, Miyamoto K, Furuhashi K, Sano S, Nakagawa Y, Ohzeki T: "A novel mutation in the renal V_2-gene in a boy with 21-trisomy"Pediatric Nephrology. (印刷中).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Li R, Nakagawa Y, Nakanishi T, Fujisawa Y, Ohzeki T: "Different responsiveness in body weight to 11β-hydroxysteroid dehydrogenase inhibition by glycyrphetic acid treatment in obese and lean zudien rats"Metabolism. (印刷中).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 大関 武彦: "小児科学新生児学テキスト:栄養(肥満),代謝疾患"診断と治療社. 991 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Liu Y-J, Nakagawa Y, Toya K, Wang Y, Saegusa H, Nakanishi T, Ohzeki T: "Effects of spironolactone on systolic blood pressure in experimental diabetic rats."Kidney International. 57. 2064-2071 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kanamori M, Nakanishi T, Arakida M, Matsumoto T, Ohzeki T, Helfenstein U, Gasser T: "Birth weight, obesity and hemoglobin Alc in Japanese school children : Results from the cross-sectional study based on the Hamamatsu Study."Hormone Research. 53(suppl 2). 177 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakagawa Y, Liu Y-J, Nakanishi T, Saegusa H, Toya K, Ohzeki T: "Analysis of 11β-hydroxysteroid dehydrogenase type 2 in the kidney of streptozotocin-induced diabetes rats"Pediatric Research. 49(6). 120A (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakanishi T, Yi M, Li R, Saegusa H, Nakagawa Y, Ohzeki T: "Effects of treatment with 11β-hydroxysteroid dehydrogenase inhibitor during infancy on body weight and glucose tolerance in adult rats."Pediatric Research. 49(6). 120A (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Endoh A, Inoue N, Katoh T, Nakamura T, Sugimura H, Ohzeki T: "A case of glycogen storage disease IA with multiple hepatic tumors managed by transcatheter arterial embolization and acarbose diet."Journal of Pediatric Gastroenterology and Nutrition. 33. 333-336 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakanishi T, Li R, Liu Z, Yi M, Nakagawa Y, Ohzeki T: "Sexual dimorphism in relationship of serum leptin and relative weight for the standard in normal-weight, but not in overweight, children as well as adolescents."European Journal of Clinical Nutrition. 55. 989-993 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fujisawa Y, Furuhashi K, Miyamoto T, Sano S, Nakagawa Y, Ohzeki T: "High-dose DDAVP partially relieved polyuria in a familial case of nephrogenic diabetes insipidus due to a novel mutation of V2 receptor gene."Hormone Research. 58. 90 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Endoh A, Nakanishi T, Ohzeki T, Kobashi G, Ishimaru Y, Kanamori M: "Serum leptin and soluble leptin receptor in normal subjects."The Endocrine Society's 84^<th> Annual Meeting, San Francisco. (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Renshan L, Nakanishi T, Fujisawa Y, Endoh A, Nakagawa Y, Ohzeki T: "Different responsiveness in body weight to 11β-hydroxysteroid dehydrogenase 1 gene."International Congress on Hormones and Cancer. Fukuoka. (2002)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2005-04-19  

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