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2002 Fiscal Year Final Research Report Summary

Establishment of Tissue Banking System on the basis of regional linkage

Research Project

Project/Area Number 12794014
Research Category

Grant-in-Aid for University and Society Collaboration

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionThe University of Tokyo

Principal Investigator

TAKAMOTO Shinichi  Cardiac Surgery, Professor, 医学部附属病院, 教授 (60137833)

Co-Investigator(Kenkyū-buntansha) TABAYASHI Koichi  The University of Tohoku, Cardiac Surgery, Professor, 医学部附属病院, 教授 (90142942)
MOTOMURA Noboru  Cardiac Surgery, Lecturer, 医学部附属病院, 講師 (40332580)
KOTSUKA Yutaka  Cardiac Surgery, Assistant Professor, 医学部附属病院, 助教授 (10126055)
TAKANASHI Minoko  Japan Red Cross, Central Blood Center, Chief Researcher, 課長(研究職)
JUJI Takeo  Japan Red Cross, Central Blood Center, President (Researcher), 所長(研究職) (20009997)
Project Period (FY) 2000 – 2002
KeywordsAllograft tissue / Cryopreservation / Tissue transplantation / Tissue bank / Network
Research Abstract

1. Founding the Network for allograft tissue procurement
We have found the Homograft Harvesting Network (HGHN) to promote the cardiovascular tissue donation and procurement. The network consisted of University of Tokyo, University of Hokkaido, University of Tohoku, Iwate Medical University, University of Akita, Saitama Medical University, University of Nagoya, Nihon Red Cross Blood Center. Each member established the procurement team with harvesting equipment within the Department, and encouraged local community to increase tissue donation.
2. Procurement and cryopreservation of the allograft tissues
We collaborated with the skin banking system in Tokyo Metropolitan area to obtain tissue dono information. Over the 3 years we could obtain 37 donors in total. Before this research project, the average number of tissue donation had been only 6 per year.
3. Shipping and transplantation of the allograft tissues.
We have used over 100 cryopreserved allograft tissues so far. Before this research project, the number of tissue usage was only 7. The research project dramatically promoted the clinical usage of cryopreserved tissue allografts.
4. Wet Lab
To share the knowledge how to handle human cardiovascular tissue the Wet Lab was performed three times, where pig hearts were used to practise how to dissect and trim the cardiac valves.

  • Research Products

    (36 results)

All Other

All Publications (36 results)

  • [Publications] Noboru Motomura, Shinichi Takamoto, Tomohiro Murakawa, Yoneda Noriko, Sakiko Shibusawa, Katsuhide Maeda, Yoshihiro Suematsu, Arata Murakami, Jun Nakajima, Yutaka Kotsuka: "Short-term result of aortic valve replacement with cryopreserved homograft valve in the University of Tokyo Tissue Bank"Artificial Organs. 26(5). 449-452 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Noriko Yoneda, Noboru Motomura, Sakiko Shibusawa, Tomohiro Murakawa, Katsuhide Maeda, Yoshihiro Suematsu, Arata Murakami, Jun Nakajima, Yutaka Kotsuka, Shinichi Takamoto: "University of Tokyo Tissue Bank (UTTB); 3 years experiences as Tissue banking system in Tokyo Metropolitan area"Progress in Transplantation. (In Press). (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tomohiro Murakawa, Jun Nakajima, Noboru Motomura, Arata Murakami, Shinichi Takamoto: "Successful allotransplantation of cryopreserved tracheal grafts with preservation of the pars mambramacea in nonhuman primates"J Thorac Cardiovasc Surg. 123. 153-160 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kazuhito Imanaka, Shunei Kyo, Hiroaki Tanabe, Haruhiko Asano, Masaaki Kato, Hiroshi Ohuchi, Masanori Ogiwara, Yuji Yokote, Shinichi Takamoto, Yasufumi Hayama: "Allograft pulmonary artery root replacement for refractory isolated pulmonic valve endocarditis"Hear and Vessels. 16. 198-200 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Arata Murakami, Shinichi Takamoto, Tetsuhiro Takaoka, Jyotaro Kobayashi, Katsuhide Maeda, Hiroo Takayama, Noboru Motomura, Tomohiro Murakawa, Minoru Ono.: "Saphenous vein homograft containing a valve as a right ventricule-pulmonary artery conduit in the modified Norwood operation"J Thorac Cardiovasc Surg.. 124(5). 1041-1042 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kazuhito Imanaka, Shunei Kyo, Shinichi Takamoto, Masaaki Kato, Hiroaki Tanabe, Hiroshi Ohuchi, Haruhiko Asano, Yuji Yokote: "Periannular abscess and aorta-left ventricular fistula after infection in the false lumen of an aortic dissection"J Thoracic Cardiovasc Surg. 124(4). 841-843 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Toshiya Ohtsuka, Shinichi Takamoto, Minoru Ono, Noboru Motomura: "Aortic root replacment and coronary interposition using a cryopreserved allograft and its branch"European Journal of Cardio-thoracic Surgery. 20. 631-632 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakuma K, Akimoto H, Yokoyama H, Iguchi A, Tabayashi K.: "Cryopreserved aortic homograft replacement in 3 patients with noninfectious inflammatory vascular disease"Jpn J Thorac Cardiovasc Surg.. 49(11). 652-655 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Iguchi A, Miura M, Tabayashi K.: "Cryopreserved aortic homograft replacement in a patient with Takayasu's arteritis"Jpn Circ J.. 63(7). 569-571 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 本村昇, 高本眞一: "同種弁移植の成績と適応"日本外科学会雑誌. 102(4). 325-329 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 本村昇: "Synergetic graft"医学のあゆみ. 200,13. 1064 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 本村昇, 高本眞一: "術後感染症対策の最近の進歩と問題点。2.心臓手術後合併症としての人工弁感染"日本外科学会雑誌. 103,12. 851-855 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 本村昇, 小野稔, 高本眞一: "組織移植(心臓弁・血管)の現状"成人病と生活習慣病. 33,1. 106-108 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 本村昇, 米田典子, 村川知弘, 澁澤沙喜子, 末松善弘, 前田克英, 村上新, 中島淳, 小塚裕, 高本眞一: "東京大学組織バンクの現状 --心臓血管組織を中心として--"骨・関節・靱帯. 14,11. 1125-1128 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 今中和人: "開心術後感染性心内膜炎"ICUとCCU. 26(8). 707-713 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中島淳, 村上新, 本村昇, 米田典子, 高本眞一: "海外における組織移植バンクの現況"今日の移植. 14(4,July). 395-400 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 今中和人, 許 俊鋭, 高本眞一, 本村昇, 米田典子, 横手祐二, 朝野晴彦, 田邊大明, 大内浩, 加藤雅明: "弁輪膿瘍を伴う大動脈弁位活動期感染性心内膜炎の外科治療"心臓. 33(11). 837-840 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小野稔, 高本眞一: "ホモグラフトの適応"Annual Review 循環器2000. 257 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Noboru Motomura, Shinichi Takamoto, Tomohiro Murakawa, Yoneda Noriko, Sakiko Shibusawa, Katsuhide Maeda, Yoshihiro Suematsu, Arata Murakami, Jun Nakajima, Yutaka Kotsuka: "Short-term result of aortic valve replacement with cryopreserved homograft valve in the University of Tokyo Tissue Bank"Artificial Organs. 26(5). 449-452 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noriko Yoneda, Noboru Motomura, Sakiko Shibusawa, Tomohiro Murakawa, Katsuhide Maeda, Yoshihiro Suematsu, Arata Murakami, Jun Nakajima, Yutaka Kotsuka, Shinichi Takamoto: "University of Tokyo Tissue Bank (UTTB) ; 3 years experiences as Tissue banking system in Tokyo Metropolitan area"Progress in Transplantation. In Press..

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tomohiro Murakawa, Jun Nakajima, Noboru Motomura, Arata Murakami, Shinichi Takamoto: "Successful allotransplantation of cryopreserved tracheal grafts with preservation of the pars mambramacea in nonhuman primates"J Thorac Cardiovasc Surg.. 123. 153-160 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kazuhito Imanaka, Shunei Kyo, Hiroaki Tanabe, Haruhiko Asano, Masaaki Kato, Hiroshi Ohuchi, Masanori Ogiwara, Yuji Yokote, Shinichi Takamoto, Yasufumi Hayama: "Allograft pulmonary artery root replacement for refractory isolated pulmonic valve endocarditis"Hear and Vessels. 16. 198-200 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kazuhito Imanaka, Shunei Kyo, Shinichi Takamoto, Masaaki Kato, Hiroaki Tanabe, Hiroshi Ohuchi, Haruhiko Asano, Yuji Yokote: "Periannular abscess and aorta-left ventricular fistula after infection in the false lumen of an aortic dissection"J Thoracic Cardiovasc Surg.. 124(4). 841-843 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Toshiya Ohtsuka, Shinichi Takamoto, Minoru Ono, Noboru Motomura: "Aortic root replacment and coronary interposition using a cryopreserved allograft and its branch"European Journal of Cardio-thoracic Surgery. 20. 631-632 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakuma K, Akimoto H, Yokoyama H, Iguchi A, Tabayashi K: "Cryopreserved aortic homograft replacement in 3 patients with noninfectious inflammatory vascular disease"Jpn J Thorac Cardiovasc Surg.. 49(11). 652-655 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Iguchi A, Miura M, Tabayashi K: "Cryopreserved aortic homograft replacement in a patient with Takayasu's arteritis"Jpn Circ J.. 63(7). 569-571 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noboru Motomura, Shinichi Takamoto: "Indications for and results of cryopreserved homograft valve replacement"J. Jpn. Surg. Soc.. 102(4). 325-329 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noboru Motomura: "Synergetic graft"Igaku no Ayumi. 200(13). 1064 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noboru Motomura, Shinichi Takamoto: "Prosthetic valve endocarditis : Complication following cardiac surgery"J. Jpn. Surg. Soc.. 103(12). 851-855 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noboru Motomura, Minoru Ono, Shinichi Takamoto: "Update of the cardiovascular tissue transplantation"Seijinbyou to Seikatsushuukanbyou. 33(1). 106-108 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Noboru Motomura, Noriko Yoneda, Tomohiro Murakawa, Sakiko Shibusawa, Yoshihiro Suematsu, Katsuhide Maeda, Arata Murakami, Jun Nakajima, Yutaka Kotsuka, Shinichi Takamoto: "Brief report of activity on University of Tokyo Tissue Bank"Hone, Kansetsu, Jintai. 14(11). 1125-1128 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kazhito Imanaka, Shunei Kyo, Shinichi Takamoto, Noboru Motomura, Noriko Yoneda, Yuji Yokote, Haruhiko Asano, Hiroaki Tanabe, Hiroshi Ohuchi, Masaaki Kato: "Surgery for active infective endocarditis with periannular abscess in the aortic position"Shinzo. 33(11). 837-840 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kazuhito Imanaka: "Diagnosis and treatment of prosthetic valve endocarditis"ICU and CCU.. 26(8). 707-713 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jun Nakajima, Arata Murakami, Noboru Motomura, Noriko Yoneda, Shinichi Takamoto: "The role of tissue bank in Europe and the United States"Transplantation Now. 14(4). 395-400 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Minoru Ono, Shinichi Takamoto: "Indication of the homograft"Annual Review Junkannki 2000. 257-261 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Arata Murakami, Shinichi Takamoto, Tetsuhiro Takaoka, Jyotaro Kobayashi, Katsuhide Maeda, Hiroo Takayama, Noboru Motomura, Tomohiro Murakawa, Minoru Ono: "Saphenous vein homograft containing a valve as a right ventricale-pulmonary artery conduit in the modified Norwood operation"J Thorac Cardiovasc Surg.. 124(5). 1041-1042 (2002)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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