2003 Fiscal Year Final Research Report Summary
Research on the recurrence prevention based on the long term prognosis of brain infarction
| Project/Area Number |
12832026
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
神経内科学
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| Research Institution | Tottori University Faculty of Medicine |
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Principal Investigator |
KOWA Hisanori Tottori Univ., Dept.of Neurology, Assistant, 医学部附属病院, 助手 (30284003)
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| Co-Investigator(Kenkyū-buntansha) |
NAKASHIMA Kenji Tottori Univ., Dept.of Neurology, Professor, 医学部, 教授 (70144673)
NAKANO Toshiya Tottori Univ., Dept.of Neurology, Assistant Professor, 医学部, 講師 (00294322)
MAEDA Masanobu Tottori Univ., Dept.of Neurology, Assistant, 医学部, 助手 (40362868)
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| Project Period (FY) |
2000 – 2003
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| Keywords | cerebral infarction / subtypes / recurrence / lacunar infarction / epidemiology / cohort study |
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| Research Abstract |
To identify determinants of recurrence after ischemic stroke in the Japanese population, we enrolled 885 patients with acute ischemic stroke that had been admitted to our community hospitals. A total of 831 cases were followed for one year after the index stroke. Patients were assigned to one of the ischemic stroke subtype groups based on the NINDS Stroke Data Bank criteria. Rates of stroke recurrence were significantly different among stroke subtype groups : 14.4% in cardioembolic infarction, 7.3% in atherothrombotic infarction (ATI), 6.2% in lacunar infarction (LI), and 7.8% in infarction of uncertain cause. Previous history of stroke was the predictor of stroke recurrence for the groups of ATI and LI patients, and diabetes mellitus was the predictor of recurrence for the group of LI patients. We concluded that the rate of recurrence and risk factors for stroke recurrence were different by stroke subtypes.
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