2000 Fiscal Year Annual Research Report

パルス電解ストップドフロー分光法による酸素ラジカルの反応特異性の解明

Research Project

Project/Area Number	12875164
Research Institution	Tokyo Institute of Technology
Principal Investigator	大坂武男東京工業大学, 大学院・総合理工学研究科, 教授 (80152099)
Co-Investigator(Kenkyū-buntansha)	北村房男東京工業大学, 大学院・総合理工学研究科, 助手 (00224973) 岡島武義東京工業大学, 大学院・総合理工学研究科, 助手 (70194347) 徳田耕一東京工業大学, 大学院・総合理工学研究科, 教授 (40016548)
Keywords	活性酸素種 / スーパーオキシドイオン / 酸素 / 過酸化水素 / 電流振動現象 / アドアトム電極 / 電気化学センサ
Research Abstract	本研究では、様々な生命現象に密接に関連している活性酸素種(スーパーオキシドイオンO_2^-,過酸化水素H_2O_2,ヒドロペルオキラジカルなど)の反応特異性の解明を目的として行われ、本年度は次の成果を得た。 1.非プロトン性非水溶媒中において、水銀電極を用いて酸素のスーパーオキシドイオンへの電解還元反応を行うことによって、特異な界面電流振動現象が起こることを発見し、そのメカニズムの詳細を解明した。 2.過酸化水素と過酢酸の電気化学的同時定量分析にはじめて成功した。 3.水銀アドアトム修飾金電極を用いて水溶液中で酸素の4電子還元により水を生成することに成功した。また、その反応メカニズムを解明した。 4.スーパーオキシドイオンの検出方法を見出した。

Research Products
(24 results)

All Other

All Publications (24 results)

[Publications] S.A.John: "Alkanethiol Structure and Supporting Electrolyte Effects on the Electrochemical and in situ Fourier Transform…"Langmuir. 16. 876-880 (2000)
[Publications] C.R.Raj: "Electrocatalytic Oxidation of NADH at the Self-Assembled Monolayer of Ni(II) Macrocycle on Gold…"Bioelectrochemistry. 51. 181-186 (2000)
[Publications] K.V.Gobi: "Anion Recognition and Electrochemical Characteristics of the Self-Assembled Monolayer of Ni (II) Azamacro…"J.Electroanal.Chem.. 485. 61-70 (2000)
[Publications] J.F.Wu: "Electrochemical Uscillatory Phenomena in the O_2/O_2^- Redox Reaction on Hg-Coated Gold Electrode"Electrochemistry. 68. 277-279 (2000)
[Publications] S.A.John: "Can N-Ethyl-N'-Octadecyl Viologen Dimerize on Octadecane thiol-Coated Gold Electrode?"Electrochim.Acta. 45. 4041-4048 (2000)
[Publications] N.Nanbu: "Adsorption of Atomic Hydrogen on a Polycrystalline Pt Electrode Surface Studied by FT-IRAS"J.Electroanal.Chem.. 485. 128-134 (2000)
[Publications] M.S.Saha: "Electrochemical Oscillatory Phenomena Based on the Electrogenerated Superoxide Ion"Jpn.J.Deuterium Sci.. 9. 35-40 (2000)
[Publications] 大坂武男: "アドミッション・ポリシーの確立と明示を"化学と教育. 48. 342 (2000)
[Publications] 大坂武男: "分子修飾電極の速度論的解析および活性酸素種の反応制御への展開"Electrochemistry. 68. 608 (2000)
[Publications] S.A.John: "Structural Effects on the Electrochemical and Spectroelectrochemical Properties of Asymmetric…"J.Electroanal.Chem.. 492. 137-144 (2000)
[Publications] M.I.Awad: "Simultaneous Electroanalysis of Peracetic Acid and Hydrogen Peroxide Using Square-Wave Voltammetry"Electrochemistry. 68. 895-897 (2000)
[Publications] K.Arihara: "Adsorption structure of the Heptyl Viologen Cation Radical on a Mercury Electrode Surface"J.Electroanal.Chem.. 488. 117-124 (2000)
[Publications] C.R.Raj: "Electroanalytical Applications of Cationic Self-Assembled Monolayers : Square-Wave Voltammetric…"Bioelectrochemistry. 52(in press). (2001)
[Publications] F.Matsumoto: "Electrochemical Reduction of Molecular Oxygen at Hg Adatom-Modified Au Electrode"J.Electroanal.Chem.. (in press). (2001)
[Publications] C.R.Raj: "Facilitated Electrochemical Oxidation of NADH and its Model Compound at Gold Electrode…"Bioelectrochemistry. 52(in press). (2001)
[Publications] M.I.Awad: "Electroanalysis of Peracetic Acid in the Presence of a Large Excess of Hydrogen Peroxide"Anal.Lett.. 34(in press). (2001)
[Publications] M.I.Awad: "Simultaneous Electroanalysis of Peroxyacetic Acid and Hydrogen Peroxide"Anal.Chem.. 73(in press). (2001)
[Publications] N.Wakabayashi: "Effect of Adsorbed Anions on the Outer-sphere Electron Transfer Reactions of Cobalt Complexes at Platinium…"J.Electroanal.Chem.. (in press). (2001)
[Publications] C.R.Raj: "Electroanalysis of Ascorbate and Dopamine at Gold Electrode Modified with Positively Charged SAM…"J.Electroanal.Chem.. (in press). (2001)
[Publications] M.S.Saha: "Current Oscillation Behavior of O_2/O_2^-Redox Couple at HMDE in Non-Aqueous Aprotic Media"J.Electroanal.Chem.. (in press). (2001)
[Publications] 大坂武男: "電位測定-参照電極・水溶液系-"Electrochemistry. 68. 610-614 (2000)
[Publications] 大坂武男(分担): "第5版電気化学便覧"丸善(株). 756 (2000)
[Publications] T.Ohsaka(分担): "Precision Polymers and Nano-Organaized Systems"Kodansha Ltd.. 350 (2000)
[Publications] 大坂武男(分担): "界面ハンドブック"(株)エヌ・ティー・エス(印刷中). (2001)

2000 Fiscal Year Annual Research Report

パルス電解ストップドフロー分光法による酸素ラジカルの反応特異性の解明

Principal Investigator

大坂 武男 東京工業大学, 大学院・総合理工学研究科, 教授 (80152099)

Research Products

[Publications] S.A.John: "Alkanethiol Structure and Supporting Electrolyte Effects on the Electrochemical and in situ Fourier Transform…"Langmuir. 16. 876-880 (2000)

[Publications] C.R.Raj: "Electrocatalytic Oxidation of NADH at the Self-Assembled Monolayer of Ni(II) Macrocycle on Gold…"Bioelectrochemistry. 51. 181-186 (2000)

[Publications] K.V.Gobi: "Anion Recognition and Electrochemical Characteristics of the Self-Assembled Monolayer of Ni (II) Azamacro…"J.Electroanal.Chem.. 485. 61-70 (2000)

[Publications] J.F.Wu: "Electrochemical Uscillatory Phenomena in the O_2/O_2^- Redox Reaction on Hg-Coated Gold Electrode"Electrochemistry. 68. 277-279 (2000)

[Publications] S.A.John: "Can N-Ethyl-N'-Octadecyl Viologen Dimerize on Octadecane thiol-Coated Gold Electrode?"Electrochim.Acta. 45. 4041-4048 (2000)

[Publications] N.Nanbu: "Adsorption of Atomic Hydrogen on a Polycrystalline Pt Electrode Surface Studied by FT-IRAS"J.Electroanal.Chem.. 485. 128-134 (2000)

[Publications] M.S.Saha: "Electrochemical Oscillatory Phenomena Based on the Electrogenerated Superoxide Ion"Jpn.J.Deuterium Sci.. 9. 35-40 (2000)

[Publications] 大坂武男: "アドミッション・ポリシーの確立と明示を"化学と教育. 48. 342 (2000)

[Publications] 大坂武男: "分子修飾電極の速度論的解析および活性酸素種の反応制御への展開"Electrochemistry. 68. 608 (2000)

[Publications] S.A.John: "Structural Effects on the Electrochemical and Spectroelectrochemical Properties of Asymmetric…"J.Electroanal.Chem.. 492. 137-144 (2000)

[Publications] M.I.Awad: "Simultaneous Electroanalysis of Peracetic Acid and Hydrogen Peroxide Using Square-Wave Voltammetry"Electrochemistry. 68. 895-897 (2000)

[Publications] K.Arihara: "Adsorption structure of the Heptyl Viologen Cation Radical on a Mercury Electrode Surface"J.Electroanal.Chem.. 488. 117-124 (2000)

[Publications] C.R.Raj: "Electroanalytical Applications of Cationic Self-Assembled Monolayers : Square-Wave Voltammetric…"Bioelectrochemistry. 52(in press). (2001)

[Publications] F.Matsumoto: "Electrochemical Reduction of Molecular Oxygen at Hg Adatom-Modified Au Electrode"J.Electroanal.Chem.. (in press). (2001)

[Publications] C.R.Raj: "Facilitated Electrochemical Oxidation of NADH and its Model Compound at Gold Electrode…"Bioelectrochemistry. 52(in press). (2001)

[Publications] M.I.Awad: "Electroanalysis of Peracetic Acid in the Presence of a Large Excess of Hydrogen Peroxide"Anal.Lett.. 34(in press). (2001)

[Publications] M.I.Awad: "Simultaneous Electroanalysis of Peroxyacetic Acid and Hydrogen Peroxide"Anal.Chem.. 73(in press). (2001)

[Publications] N.Wakabayashi: "Effect of Adsorbed Anions on the Outer-sphere Electron Transfer Reactions of Cobalt Complexes at Platinium…"J.Electroanal.Chem.. (in press). (2001)

[Publications] C.R.Raj: "Electroanalysis of Ascorbate and Dopamine at Gold Electrode Modified with Positively Charged SAM…"J.Electroanal.Chem.. (in press). (2001)

[Publications] M.S.Saha: "Current Oscillation Behavior of O_2/O_2^-Redox Couple at HMDE in Non-Aqueous Aprotic Media"J.Electroanal.Chem.. (in press). (2001)

[Publications] 大坂武男: "電位測定-参照電極・水溶液系-"Electrochemistry. 68. 610-614 (2000)

[Publications] 大坂武男(分担): "第5版電気化学便覧"丸善(株). 756 (2000)

[Publications] T.Ohsaka(分担): "Precision Polymers and Nano-Organaized Systems"Kodansha Ltd.. 350 (2000)

[Publications] 大坂武男(分担): "界面ハンドブック"(株)エヌ・ティー・エス(印刷中). (2001)

大坂武男東京工業大学, 大学院・総合理工学研究科, 教授 (80152099)