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2003 Fiscal Year Final Research Report Summary

3D micro/nano structures for micro-chemo-mechatoronics

Research Project

Project/Area Number 13124202
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionThe University of Tokyo

Principal Investigator

NAKAO Masayuki  University of Tokyo, Dept. of Engineering, Professor, 大学院・工学系研究科, 教授 (90242007)

Co-Investigator(Kenkyū-buntansha) MITSUISHI Mamoru  University of Tokyo, Dept. of Engineering, Professor, 大学院・工学系研究科, 教授 (90183110)
MATSUMOTO Kiyoshi  University of Tokyo, Dept. of Engineering, Associated Professor, 大学院・理工専攻, 助教授 (10282675)
Project Period (FY) 2001 – 2003
Keywords3-dimentional fine structure / electron beam deposition method / focused ion beam machining / Laser welding / sintered glass / near-field optics
Research Abstract

The purpose of this research is establishing the technology to create the 3-dimensional fine structures for micro-chemo-mechatronics with semiconductor processing technology and machining technology.
In addition to the conventional MEMS technique and chemical modification technology, mechanical ultra-fine processing technology, such as electrolysis polish, electrical discharge machining, beam deposition, assembly, bonding, embossing, injection molding, and so on is used to create microchemistry instruments equipped with the 3-dimensional fine structures for chemical analysis. In this research, we classified micro/nano structure into needlelike, tubular, and channel-like structure as the following items.
Needlelike structure : The electron beam depositing (EBD) method which generates carbon nano-wire using the beam of a scanning electron microscope was developed as manufacturing technology of the nano meter scaled needlelike structure. Using this needlelike structure, handing tool of DNA … More and scattering probe for near-field optical microscope was developed. Furthermore, conductive control of an EBD probe was tried for the application to a micro electrode, micro sensor, etc. In order to generate crystalline graphite structure instead of amorphous EBD, we arranged the source feeder of carbon, a catalyst, and the heating equipment for activation of the catalyst in an electron microscope. As the result, the carbon deposition considered to be crystalline was generable.
Tubular structure : Research which processes a micro glass pipe using focused ion beam and produces tubular structure has been done. As an example of application, micro pipet which performs fixed quantity dispensing by preparing hydrophilic area of the fixed volume of pico liter order in the interior of the pipet was developed. And also, the system which generates droplet on a substrate with the combination of the micro pipet verticaly drived by the piezo-electric device, and the substrate with controlled hydrophilicity was developed.
Channel-like structure : The mechanical processing method for manufacturing glass channel chips mainly manufactured by the chemical technique such as a wet or dry etching at this stage, at high speed and low cost has been developed for mass-production of micro chemical analysis instruments. For example, processing method which coat a substrate with the glass flit by an injector, form channels, sinters and produces a glass chip was tried. Furthermore, in order to treat the reagent which makes glass corrode, and the reaction which generates excessive heat and pressure, the metal micro-reactor excellent in heat transfer and shock resistance was developed. It was shown that combining the cutting method for formation of the groove, and the bonding technology of the cover by the YAG laser-welding method, the multilayer chip made from stainless steel with 400 micrometers width channels is producible. Less

  • Research Products

    (26 results)

All Other

All Publications (26 results)

  • [Publications] Takeshi Ooi, et al.: "Metal Microreactors for Chemical Synthesis Multilayered by Laser Welding"Proceeding of the International Symposium on Microchemistry and Microsystem 2003. 33-34 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Ooi, K.Kasuya, K.Tsuchiya, T.Hamaeuchi, M.Nakao: "Pinpoint chemical vapor deposition of carbon nanowire for Nanometer-scale electronic devices"Proc.ASPS Annual meeting 2003. (CD-ROM). (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Tsuehiya, et al.: "Precise gastight sealing for bio/chemical microchip"Proc.ASPS Annual meeting 2003. (CD-ROM). (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Tsuchiya, A.Yamaji, T.Ooi, T.Hamaguchi, M.Nakao: "A Laser Welded Multilayered Metal Micro-Reactor for Chemical Synthesis"MICRO SYSTEM Technologies 2003. 320-327 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masaaki FUJISAKI, et al.: "ON-CHIP CULTURE FOR MONITORING SINGLE CELLS"EMBEC '02. 302-303 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takeshi OOI, Yusuke OKABE, Masayuki NAKAO, Keisuke IWATA: "Laminated electrodes chip far pulse-immunoassay"Micro Total Analysis Systems. 121-123 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 竹中良, 大井健, 中尾政之, 長森英二, 福井希一: "遺伝子封入用マイクロカプセルの開発"医用電子と生体工学. 40. 81-81 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masayuki NaKao, Takesni Ooi, Kensuke Tsuchiva: "A nano channel is made to a microchip"(CD-ROM). (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kensuke Tsuchiya, Takeshi Ooi, Yuki Sakamaki, Masavuki Nakao: "High aspect ratio SNOM probe fabricated using Electron Beam Deposition and Focused Ion Beam"Proceedings from ASPE 2002 Annual Meeting. 27. 20-23 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 藤岡聡太, 大井健, 中尾政之, 畑村洋太郎: "ナノメータサイズのプローブを用いた単一DNAの切断と断片の単離"医用電子と生体工学. 39巻特別号. 280-280 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中尾政之, 大井健: "ナノチャネルとナノツール"化学工業. 52. 18-22 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中尾政之, 大井健, 土屋健介: "マイクロチップにナノチャネルを作る"BME(Bio Medical Engineering). 15. 57-62 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Ooi: "3D-nano Wire-frame for Handling and Observing a single DNA Probe"Proc. of MEMS.'00. 580-583 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masayuki Nakao, Takeshi Ooi, Kensuke Tsuchiya: "A nano channel is made to a microchip"BME (Bio Medical Engineering). Vol.15, No.10. 57-62 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masayuki Nakao, Takeshi Ooi: "A nano channel and a nano tool"Chemical industry. Vol.52, No.1. 18-22 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sota Fujioka, Takeshi Ooi, Masayuki Nakao, Yotaro Hatamura: "Cutting of single DNA and isolation of a fragment using the probe of nano meter size"BME. Vol.39. 280 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yuke Sakamaki, Takeshi Ooi, Masayuki Nakao, Yotaro Hatamura: "Development of the near-field optical microscope using a high aspect ratio scattering probe"BME. Vol.39. 278 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masayuki Nakao, Takeshi Ooi, Kensuke Tsuchiya: "A nano channel is made to a microchip"BME (Bio Medical Engineering). Vol.15, No.10. 57-62 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ryo Takenaka, Takeshi Ooi, Masayuki Nakao, Kiichi Fukui: "Development of the microcapsule for gene enclosure"The 6th conference of chemistry and micro nano system. 51 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ryo Takenaka, Takeshi Ooi, Masayuki Nakao, Eiji Nagamori, Kiichi Fukui: "Development of the microcapsule for gene enclosure"BME. Vol.40. 81 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshi OOI, Yusuke OKABE, Masayuki NAKAO, Keisuke IWATA: "Laminated electrodes chip for pulse-immunoassay"Micro Total Analysis Systems 2002. 121-123 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masaaki FUJISAKI: "ON-CHIP CULTURE FOR MONITORING SINGLE CELLS"EMBEC'02. 302-303 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshi Ooi: "Metal Microreactors for Chemical Synthesis Multilayered by Laser Welding"Proceeding of the International Symposium on Microchemistry and Microsystem 2003. 33-34 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T.Ooi, K.Kasuya, K.Tsuchiya, T.Hamaguchi, M.Nakao: "Pinpoint chemical vapor deposition of carbon nanowire for Nanometer0scale electronic devices"Proc. ASPE Annual meeting 2003, CD-ROM. (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K.Tsuchiya: "Precise gastight sealing for bio/chemical microchip"Proc. ASPE Annual meeting 2003, CD-ROM. (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K.Tsuchiya, A.Yamaji, T.Ooi, T.Hamaguchi, M.Nakao: "A Laser Welded Multilayered Metal Micro-Reactor for Chemical Synthesis"MICRO SYSTEM Technologies 2003. 320-327 (2003)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2005-04-19  

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