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2002 Fiscal Year Final Research Report Summary

Preparation of DNA films showing a large anisotropic conductivity

Research Project

Project/Area Number 13450388
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field 高分子構造・物性(含繊維)
Research InstitutionTokyo Institute of Technology

Principal Investigator

OKAHATA Yoshio  Tokyo Institute of Technology, Professor, 大学院・生命理工学研究科, 教授 (80038017)

Co-Investigator(Kenkyū-buntansha) FUKUSAWA Hiroyuki  Tokyo Institute of Technology, Research Associate, 大学院・生命理工学研究科, 助手 (60345395)
KAWASAKI Takayoshi  Tokyo Institute of Technology, Research Associate, 大学院・生命理工学研究科, 助手 (60334504)
MORI Toshiaki  Tokyo Institute of Technology, Associate Professor, 大学院・生命理工学研究科, 助教授 (50262308)
Project Period (FY) 2001 – 2002
KeywordsDNA-aligned film / electron conductivity / DNA from sermon testes / cohm-type electrode
Research Abstract

The purpose of this project is to prepare a DNA aligned film that shows a large anisotropic conductivity along DNA strands in the film. DNA is believed to be having an ability of electron transfer, because DNA has many π-electrons within the stacked base pairs. We prepared DNA-lipid films and measured their conductivities. In this research, we tried to measure the conductivity of a single DNA molecule as a nanowire. We have prepared DNA-nanowires by using Langmuir-Blodgett method, and observed aligned DNA -nanowires by a fluorescent microscopy. Further, the electron conductivity of DNA-nanowires was also measured on an interdigitated microcuit. We found that DNA-nanowires are good semiconductor (0.1-1S cm-1) from conductivity measurements.

  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] S.Fukusho, H.Furusawa, Y.Okahata: "In vitro Selection and Evaluation of RNA Aptamers that recognize Arginine-rich motif Model Peptide on a Quartz-crystal Microbalance"Chem.Commun.. 88-89 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Mori, M.Li, A.Kobayashi, Y.Okahata: "Reversible Control of Enzymatic Transglycosylations in Supercritical Fluoroform using a Lipid-Coated β-D-Galactosidase"J.Am.Chem.Soc.. 124. 1188-1189 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Hoshino, S.Tajima, H.Nakayama, Y.Okahata: "A RNA-aligned Film prepared from a RNA-Lipid Complex"Maromolecular rapid Commun.. 23. 253-255 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Furusawa, Y.Kitamura, N.Hagiwara, T.Turimoto, Y.Okahata: "Binding Kinetics of the Toroidal-Shaped PCNA to DNA Strands on a 27 MHz Quartz-Crystal Microbalance"ChemPhysChem.. No.5. 446-448 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Matsuno, Y.Okahata: "Direct Monitoring of DNA Cleavages catalyzed by an ATP-dependent Deoxyribonuclease on a 27 MHz Quartz-Crystal Microbalance"Chem.Commun. 470-471 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S. Fukusho, H. Furusawa, and Y. Okahata: "In vitro Selection and Evaluation of RNA Aptamers that recognize Arginine-rich motif Mode1 Peptide on a Quartz-crystal Microbalance"Chem. Commun.. 88-89 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y. Hoshino, S. Tajima, H. Nakayama, and Y. Okahata: "A RNA-aligned Film prepared from a RNA-Lipid Complex"Macromolecular rapid Commun.. 23. 253-255 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H. Furusawa, Y. Kitamura, N. Hagiwara, T. Turimoto, and Y. Okahata: "Binding Kinetics of the Toroidal-Shaped PCNA to DNA Strands on a 27 MHz Quartz-Crystal Microbalance"Chem Phys Chem.. No.5. 446-448 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H. Matsuno and Y. Okahata: "Direct Monitoring of DNA Cleavages catalyzed by an ATP-dependent Deoxyribonuclease on a 27 MHz Quartz-Crystal Microbalance"Chem. Commun.. 470-471 (2002)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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