2003 Fiscal Year Final Research Report Summary
Development of a three-dimensional irradiation system for intensity-modulated radiotherapy and its clinical application.
| Project/Area Number |
13470183
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | KYOTO UNIVERSITY |
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Principal Investigator |
NAGATA Yasushi Kyoto University, Associate Professor, 医学研究科, 助教授 (10228033)
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| Co-Investigator(Kenkyū-buntansha) |
MIZOWAKI Takashi Kyoto University, Assistant Professor, 医学研究科, 助手 (90314210)
MITSUMORI Michihide Kyoto University, Lector, 医学研究科, 講師 (10263089)
HIRAOKA Masahiro Kyoto University, Professor, 医学研究科, 教授 (70173218)
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| Project Period (FY) |
2001 – 2003
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| Keywords | Intensity modulated radiotherapy / IMRT / Three-dimensional radiotherapy / Prostate cancer / Body frame / Head and neck cancer / QA / Respiratory gating |
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| Research Abstract |
To establish an integrated three-dimensional irradiation system for IMRT (intensity-modurated radiotherapy), the following research had been performed.
1. Respiratory gating system
To expand the stereotactic radiotherapy for a patient with poor respiratory function, a gating system is ideal. In this study, a flow and a pressure gated signal generators was established for this purpose.
2. Clinical application of stereotactic radiotherapy
As many as 95 patients have been treated with this technique. The clinical results of primary lung cancer and secondary lung cancer was evaluated respectively.
3. Quality assurance of IMRT
An original phantom for the clinical application of IMRT for head and neck cancer was developed, and its quality assarance was performed. In general, the dose discrepancy was maintained within 5% between planned dose and measured dose.
4. Clinical application of IMRT
IMRT have been performed mainly for prostate cancer and head & neck cancers : The setup error was measured for prostate cancer, and the effect of metallic artifact and change in outline were evaluated for head and neck cancer.
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