2003 Fiscal Year Final Research Report Summary
Development of a SIgA measurement kit for monitoring of risk of URTI
| Project/Area Number |
13558003
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
体育学
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| Research Institution | University of Tsukuba (2003)
The University of Tokyo (2001-2002) |
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Principal Investigator |
KONO Ichiro University of Tsukuba, Institute of Health & Sport Sciences, Professor, 体育科学系, 教授 (00132994)
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| Co-Investigator(Kenkyū-buntansha) |
AKAMA Takeo Japan Woman's College of Physical Education, Department of Physical Education, Associate Professor, 体育学部, 助教授 (60212411)
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| Project Period (FY) |
2001 – 2003
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| Keywords | URTI / SIgA / sports / athletes / immunity / saliva |
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| Research Abstract |
Development of SIgA kit
We tried to develop a SIgA measurement kit by using commercially available monoclonal antibody. However, we could not develop an optimal system of SIgA measurement, because of the titer and/or epitope of monoclonal antibody. So, we are trying to make some monoclonal antibodies to be able to use TIA. Now we are screening the antibody
Determination of the relationship between SIgA level and URTI
Our research which we pointed out the relationship between SIgA and URTI, was published in Japanese Journal of Clinical Sports Medicine. Furthermore, another research which dealt with changes of SIgA and physical and mental stress was published in Medicine and Science in Spurts and Exercise. Resulting from this study, we clarified that there is a certain relationship between SIgA level and risk of URTI, we may be able to apply the relationship to prevent URTI in athletes
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