2003 Fiscal Year Final Research Report Summary
A study on neuropathology of AIDS patients in Africa
| Project/Area Number |
13576021
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Legal medicine
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| Research Institution | Saga University |
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Principal Investigator |
KIBAYASHI Kazuhiko Saga University, Faculty of Medicine, Professor, 医学部, 教授 (20244113)
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| Co-Investigator(Kenkyū-buntansha) |
YONEMITSU Kose Kumamoto University, Faculty of Medicine, Lecturer, 医学部, 講師 (10128332)
SHOJO Hideki Saga University, Faculty of Medicine, Research Associate, 医学部, 助手 (60284626)
TSUNENARI Shigeyuki Kumamoto University, Faculty of Medicine, Professor, 医学部, 教授 (80040202)
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| Project Period (FY) |
2001 – 2003
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| Keywords | international exchange of researchers / Tanzania / AIDS / HIV / neuropathology / tuberculosis / cryoticococosis / toxoplasmosis |
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| Research Abstract |
The objective of this study was to examine the neuropathological changes in the brain of patients infected with human immunodeficiency virus (HIV) in Dar es Salaam, Tanzania. HIV infection was identified in 78 (35.8%) of 218 patients selected from forensic autopsies. Neuropathological findings were observed in 35 (44.9%) of 78 HIV infected patients these include lymphocytic meningitis 20, bacterial meningitis 3, tuberculous brain abscess 4, toxoplasma encephalitis 3, cryptococcal meningitis 2, basal ganglia calcification 3. HIV encephalitis, lymphoma, and cytomegalovirus encephalitis could not be found in this study. These results provided information on the likely diagnostic possibilities to be considered in the evaluation and management of HIV infected patients with neurological symptoms in Tanzania.
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