2003 Fiscal Year Final Research Report Summary
Specification of the factor in a liver cell required for multiplication of hepatitis C virus
| Project/Area Number |
13670521
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Gastroenterology
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
CHAYAMA Kazuaki Hiroshima University, Graduate School of Biomedical Science, Professor, 大学院・医歯薬学総合研究科, 教授 (00211376)
|
|---|
| Project Period (FY) |
2001 – 2003
|
| Keywords | hepatitis C virus / chronic hepatitis / acute hepatitis / full length clone / replicon |
|---|
| Research Abstract |
Hepatitis C virus infection is a serious health problem worldwide. As the hepatitis C virus infects only humans and chimpanzees, establishment of reliable culture system is necessary to study this important pathogen. We cloned a full length genotype 1b cDNA clone of the hepatitis C virus from a patient who developed acute hepatitis C. This cDNA clone was used to construct several replicon clones and infectious clones. These constructs should be useful to study the hepatitis C virus.
|
Research Products
(31 results)
