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2004 Fiscal Year Final Research Report Summary

Nosological and Diagnostic Study of Other Pervasive Developmental Disorders

Research Project

Project/Area Number 13670983
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionThe University of Tokyo

Principal Investigator

KURITA Hiroshi  The University of Tokyo, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 (30010466)

Project Period (FY) 2001 – 2004
Keywordsatypical autism / child psychiatry / head circumference / pervasive developmental disorder (PDD) / PDD not otherwise specified (PDDNOS)
Research Abstract

This study consists of 7 clinical studies on pervasive developmental disorder (PDD) not other wise specified (PDDNOS) or atypical autism (AA), which are the majority of PDD and many of which are high-functioning (IQ【greater than or equal】70).
Study I : Childhood Autism Rating Scale-Tokyo Version (CARS-TV) total score was compared between 430 PDD children and 75 children with mental retardation and no history of PDD (MR) and among 4 PDD subgroups (i.e., autistic disorder [AD], childhood disintegrative disorder [CDD], Asperger's disorder [ASD], PDDNOS). The total score was significantly higher in PDD than MR, AD and CDD than PDDNOS and ASD, and PDDNOS than ASD. Its cutoffs were 25.5/26 for PDD/MR and 30/30.5 for AD/PDDNOS.
Study II : Autism Spectrum Quotient Japanese Version (AQ-J) score had good reliability, was significantly higher in 15 male adolescents with high-functioning PDD (HPDD) than 49 controls, and its HPDD cutoff was 26.
Study III : When 53 high-functioning AA children and 21 h … More igh-functioning childhood autism children were compared on CARS-TV items with IQ and CARS TV total score controlled for, the former was significantly less abnormal in interpersonal relations and general impressions and significantly stronger in anxiety reaction.
Study IV : Head circumference was not significantly different among 143 AA, 95 CA and normative data in infants, while it was significantly larger in females than males in both AA and CA groups.
Study V : When IQ, gender and age matched (n=22) high-functioning PDDNOS patients and attention-deficit hyper-activity disorder patients were compared on WISC-R, the former was significantly more inferior in verbal IQ, verbal comprehension, vocabulary, comprehension, and more excellent in block design, coding and processing speed.
Study VI : In 19 AD, 59 PDDNOS, 24 MR without PDD history, in whom the Child Behavior Questionnaire-Revised (CBQ-R) was administered in 4 to 6 years and 24-36 months later, there was no transaction between diagnosis and time and there existed IQ increase and CBQ-R score decrease in the three groups.
Study VII : At average 20 years, 41 AA was significantly lower in the degree of autism and higher in the rate of high-functioning than 83 CA. Less

  • Research Products

    (13 results)

All 2004 2003 2002 2001 Other

All Journal Article (12 results) Book (1 results)

  • [Journal Article] 広汎性発達障害(PDD)児とPDD非合併精神遅滞児の経時的発達変化の比較2004

    • Author(s)
      井筒節, 加藤星花, 長田洋和, 栗田広
    • Journal Title

      臨床精神医学 33

      Pages: 65-69

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] A comparison of high-functioning atypical autism and childhood autism by Childhood Autism Rating Scale-Tokyo Version2004

    • Author(s)
      Kanai C, Koyama T, Kato S, Miyamoto Y, Osada H, Kurita H
    • Journal Title

      Psychiatry and Clinical Neurosciences 58

      Pages: 217-221

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] A comparative study of longitudinal development between children with pervasive developmental disorder (PDD) and children with mental retardation without PDD.2004

    • Author(s)
      Izutsu, T., Kato, S., Osada, H., Kurita, H.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 33

      Pages: 65-69

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] A comparison of high-functioning atypical autism and childhood autism by Childhood Autism Rating Scale-Tokyo Version.2004

    • Author(s)
      Kanai, C., Koyama, T., Kato, S., Miyamoto, Y., Osada, H., Kurita, H
    • Journal Title

      Psychiatry and Clinical Neurosciences 58

      Pages: 217-221

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Childhood Autism Rating Scale-Tokyo Version for screening pervasive developmental disorders2003

    • Author(s)
      Tachimori H, Osada H, Kurita H
    • Journal Title

      Psychiatry and Clinical Neurosciences 57

      Pages: 113-118

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 自閉性スペクトル指数日本版(AQ-J)の信頼性と妥当性2003

    • Author(s)
      栗田広, 長田洋和, 小山智典, 宮本有紀, 金井智恵子, 志水かおる
    • Journal Title

      臨床精神医学 32

      Pages: 1235-1240

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Childhood Autism Rating Scale-Tokyo Version for screening pervasive developmental disorders.2003

    • Author(s)
      Tachimori, H., Osada, H., Kurita, H.
    • Journal Title

      Psychiatry and Clinical Neurosciences 57

      Pages: 113-118

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Reliability and validity of the Autism-Spectrum Quotient Japanese Version (AQ-J).2003

    • Author(s)
      Kurita, H., Osada, H., Koyama, T., Miyamoto, Y., Kanai, C., Shimizu, K.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 32

      Pages: 1235-1240

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 広汎性発達障害の診断補助尺度としての小児行動質問表改訂版(CBQ-R)の有用性に関する研究2001

    • Author(s)
      井筒節, 長田洋和, 立森久照, 長沼洋一, 加藤星花, 堤敦朗, 栗田広, 太田昌孝
    • Journal Title

      臨床精神医学 30

      Pages: 525-532

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] A study on the utility of the Child Behavior Questionnaire Revised (CBQ-R) as an adjunctive diagnostic scale of pervasive developmental disorders.2001

    • Author(s)
      Izutsu, T., Osada, H., Tachimori, H., Naganuma, Y., Kato, S., Tsutsumi, A., Kurita, H., Ohta, M.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 30

      Pages: 525-532

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Cognitive and symptom profiles in high-functioning PDDNOS and attention-deficit/hyperactivity disorder

    • Author(s)
      Koyama T, Tachimori H, Osada H, Kurita H
    • Journal Title

      Journal of Autism and Developmental Disorders (in press)

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Cognitive and symptom profiles in high-functioning pervasive developmental disorder not otherwise specified and attention-deficit/hyperactivity disorder.

    • Author(s)
      Koyama, T., Tachimori, H., Osada, H., Kurita, H.
    • Journal Title

      Journal of Autism and Developmental Disorders (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] 特定不能の広汎性発達障害.現代児童青年精神医学(山崎晃資,牛島定信,栗田広,青木省三編)2002

    • Author(s)
      栗田広
    • Total Pages
      151-155
    • Publisher
      永井書店
    • Description
      「研究成果報告書概要(和文)」より

URL: 

Published: 2006-07-11  

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