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2003 Fiscal Year Final Research Report Summary

Research on Development and Validity of New Therapeutic Strategy for Anorexia Nervosa

Research Project

Project/Area Number 13671020
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionKagoshima University

Principal Investigator

NOZOE Shin-ichi  Kagoshima University, Graduate School of Medical and Dental Sciences, Professor, 大学院・医歯学総合研究科, 教授 (10117533)

Co-Investigator(Kenkyū-buntansha) NARUO Tetsuro  Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 (70244233)
Project Period (FY) 2001 – 2003
Keywordsanorexia nervosa / bulimia nervosa / starvation / chronicity / team approach / stress coping / bringing-up experience / early prevention
Research Abstract

1)Examination about chronic patients with eating disorders (ED) whose ill period passed ten years or more :
Among 31 patients with chronic ED we found 7 restrictive anorexia nervosa patients (AN-R), 12 anorexia nervosa with binge eating and purging (AN-BP), 6 bulimia nervosa with purging (BN-P), 1 bulimia nervosa without purging (BN-NP) and 5 eating disorders not otherwise specified (EDNOS). These findings indicate that more than 80% of the chronic patients are exposed to long term of severe malnutrition which have great impact on physiological and psychological state relating with abnormal eating.
2)Examination about an eating disorder patient's bringing-up experience :
As compared with the control group, "refusal" of the ED group was significantly higher in the father and the mother, and the patients did not feel "emotion-warmth". Moreover, the father's (results serious consideration) and (excessive meddling) of "overprotection" were significantly low, and the father thought that unconcern and an attitude (presence is thin) of noninterference were taken.
3)Proposal about the new medical treatment program based on the research results :
Since the action by disorder of the mind-and-body balance by repetition of overeating and vomiting makes correspondence much more difficult, it is better to consider the team medical treatment by the hospitalization which that it can do burns. Thus, the early treatment by early detection is most important and effective and parents who have familiar problems should also be supported from the side.

  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] Naruo T, Nakabeppu Y, Deguchi D, Nagai N, Tsutsui J, Nakajo M, Nozoe S: "Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysis"BMC Psychiatry. 1. 2 (2001)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nagai N, Naruo T, Homan H, Tatebe Y, Muranaga T, Munemoto T, Yasuhara D, Deguchi D, Nozoe S: "Effectiveness of multidisciplinary team approach and prognosis of inpatients with eating disorders."Psycho-neuro-endocrino-immunology. 1241. 137-141 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tanaka M, Naruo T, Nagai N, Kuroki N, Shiiya T, Nakazato M, Matsukura S, Nozoe S: "Habitual binge/purge behavior influences circulating ghrelin levels in eating disorders."Journal of Psychiatry Research. 37. 17-22 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yasuhara D, Naruo T, Nagai N, Tanaka M, Muranaga T, Nozoe S: "Insulinogenic index at 15 min as a marker of nutritional rehabilitation in anorexia nervosa."American Journal of Clinical Nutrition. 77. 292-299 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Naruo T, Nakabeppu Y, Deguchi D, Nagai N, Tsutsui J, Nakajo M, Nozoe S: "Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysis"BMC Psychiatry. 1. 2 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nagai N, Naruo T, Homan H, Tatebe Y, Muranaga T, Munemoto T, Yasuhara D, Deguchi, D, Nozoe S: "Effectiveness of multidisciplinary team approach and prognosis of inpatients with eating disorders."Psycho-neuro-endocrino-immunology. 1241. 137-141 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tanaka M, Naruo T, Nagai N, Kuroki N, Shiiya T, Nakazato M, Matsukura S, Nozoe S: "Habitual binge/purge behavior influences circulating ghrelin levels in eating disorders."Journal of Psychiatry Research. 37. 17-22 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yasuhara D, Naruo T, Nagai N, Tanaka M, Muranaga T, Nozoe S: "Insulinogenic index at 15 min as a marker of nutritional rehabilitation in anorexia nervosa."American Journal of Clinical Nutrition. 77. 292-299 (2003)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2005-04-19  

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