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2002 Fiscal Year Final Research Report Summary

Evaluation of the guidelines for infection control and prevention, which was made for national university hospitals in Japan

Research Project

Project/Area Number 13672418
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory medicine
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

ICHIYAMA Satoshi  Graduate School of Medicine, Professor, 医学研究科, 教授 (30223118)

Co-Investigator(Kenkyū-buntansha) SENDA Kazuyoshi  Graduate School of Medicine, Instructor, 医学研究科, 助手 (90324649)
KUDO Toyoichiro  Graduate School of Medicine, Instructor, 医学研究科, 助手 (80324622)
LINUMA Yoshitsugu  Graduate School of Medicine, Assistant Professor, 医学研究科, 講師 (90303627)
HORII Toshinobu  Hamamatsu University School of Medicine, Instructor, 医学部, 助手 (80283430)
Project Period (FY) 2001 – 2002
KeywordsHospital Infection / Infection Control Guideline / Centers for Disease Control and Prevention / Surveillance / Infectious Disease Specialist / Infection Conlrol Doctor / Recommendation / Infection Control Team
Research Abstract

Head investigator, Satoshi Ichiyama, headed the committee set up to make the guidelines for infection control and prevention for the National University Hospitals in Japan. The guidelines were made with referring the guidelines of Centers of Disease Control and Prevention (CDC) modified to fit the hospitals and were completed at November 2001. The guidelines comprises five parts: Standard precautions and transmission-based precautions; Prevention and control of specific pathogens (I.e., Tuberculosis, Measles, Legionella); Prevention of specific nosocomial infections (I.e., Urinary Tract Infection, Ventilator Associated Pneumonia, Surgical Site Infection); Environmental Infection Control; Others (I.e., Management of Intravascular Catheter-related Infections, Management of Occupational Exposures to HBV, HCV, and HIV). The guidelines were revised at December 2002, and the guideline for food poisoning was added
Infection Control Doctors (ICD), who were specialists for infectious diseases, practiced the infection control based on this guidelines at Kyoto University Hospital. Until December 2002, a total of 636 cases were investigated. Among them, 500 had abnormal laboratory data associated with severe infectious diseases, 98 had consultation to ICD, and 28 had inappropriate use of antibiotics. Appropriate diagnosis and treatment were recommended on 62% and 69% of the cases, respectively, and the diagnosis and treatment were modified according to the recommendations on 56% and 51% among them, respectively. Furthermore, appropriate infection control practices were recommended on 14% of the cases, with 85% modification. In conclusion, many of medical doctors in Japan had only inadequate knowledge of infectious diseases and infection control, therefore, ICD should commit to the diagnosis and treatment of infectious diseases for the compliance of infection control guidelines

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] Hisashi Baba: "Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity"Infect Immun. 70. 107-113 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yoshitsugu Iinuma: "Evaluation of a commercially available serologic assay for antibodies against tuberculosis-associated glycolipid antigen"Clin Chem Lab Med. 40. 832-836 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Satoshi Ichiyama: "The role of microbiology laboratory information for the control of nosocomial infections"Rinsho Byori. 121. 193-197 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takashi Saito: "Biliary bacteria in living related liver transplant recipients : Microbiology and rapid detection system using flow cytometry"Clin Chem Lab Med. 41. 159-163 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takashi Saito: "Anaerobic bacteremia : the yield of positive anaerobic blood cultures : patient characteristics and potential risk factors"Clin Chem Lab Med. 41. 293-297 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yoshitsugu Iinuma: "Evaluation of the BDProbeTec ET System for direct detection of Mycobacterium tuberculosis in Respiratory samples in comparison to the Cobas Amplicor PCR"Eur J Clin Microbiol Infecti Dis. (in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 一山 智: "病院感染対策ガイドライン(改訂版)"国立大学医学部附属病院感染対策協議会. 160 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Baba H, Kawamura,I, Kohda,C, Nomura,T, Ito,Y, Kimoto,T, Watanabe,I, Ichiyama,S, Mitsuyama,M: "Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity"Infect Immun. 70. 107-113 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Iinuma,Y, Senda,K, Takakura,S, Ichiyama,S, Tano,M, Abe,T, Yamamoto,T, Nakashima,K, Baba,H, Hasegawa,Y, Shimokata,K.: "Evaluadon of a commercially available serologic assay for antibodies against tuberculosis-associated glycolipid antigen"Clin Chem Lab Med. 40. 832-836 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ichiyama,S: "The role of microbiology laboratory information for the control Nosocomial infections"Rinsho Byori. 121. 193-197 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Saito,T, Senda,K, Takakura,S, Fujihara,N, Kudo,T, Iinuma,Y, Kiuchi,T, Tanimoto,M, Ichiyama,S: "Biliary bacteria in living related liver transplant recipients: Microbiology and rapid detection system using flow cytometry"Clin Chem Lab Med. 41. 159-163 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Saito,T, Senda,K, Takakura,S, Fujihara,N, Kudo,T, Iinuma,Y, Fujita,N, Komori,T, Baba,H, Horii,T, Matsuoka,K, Tanimoto,M, Ichiyama,S: "Anaerobic bacteremia; the yield of positive anaerobic blood cultures: patient characteristics and potential risk factors"Clin Chem Lab Med.. 41. 293-297 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Iinuma,Y, Senda,K, Fujihara,N, Saito,T, Takakura,S, Shimojima,M, Kudo,T, Ichiyama,S: "Evaluation of the BDProbeTec ETSystem for direct detection of Mycobacterium tuberculosis in Respiratory samples in comparison to the Cobas Amplicor PCR"Eur J Clin Microbiol Infecti Dis. in press.

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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