2002 Fiscal Year Final Research Report Summary
Effects of swimming on blood pressure and endotheliall function in mild hypertensive subjects
| Project/Area Number |
13672542
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical nursing
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| Research Institution | Nursing College Wakayama Medical University |
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Principal Investigator |
MIZUTA Mayumi Nursing College Wakayama Medical University, Lecturer, その他部局等, 講師 (00300377)
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| Co-Investigator(Kenkyū-buntansha) |
ARITA Mikio Nursing College Wakayama Medical University, Professor, その他部局等, 教授 (40168018)
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| Project Period (FY) |
2001 – 2002
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| Keywords | endothelial function / swimming / hypertension |
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| Research Abstract |
Background and Objective: Though swimming is recommended against the hypertension (HT), there are few reports that effect of swimming on blood pressure was examined scientifically. In this study, effects of swimming on blood pressure and the endothe-lial function in subje-cts with mild hypertension were examined.
Methods: Subjects(mild HT group(7 women) and normal tension group(9 women)) participated in the study and exercised by swimming (50%VO2max for 60 minutes, 2-3 tim-es/week) for 3 months. Blood pressure, function of vascular endothelial cells (flow-mediated dilatation), BMI, total cholesterol and HDL cholesterol were compared bef-ore and after the exercise swimming.
Results: Diastolic blood pressure decreased significantly after the exercise(miId HT group : 88,4 ± ll.lmmHg vs 78.7 ± 5.9mmHg, normal tension group:67.9 ± 9.5mmHg vs 61.6± 9.lmnHg, p <0.05) , and flow-mediated dilatation (% FMD) increased in both groups by swimming(mild HT group : 12.0 ± 4.2 % vs 17.7 ± 4.3 %, normal tension group:12.9 ±5.7% vs 19.4 ± 8.9%, p<0.05). Though there was no significant change in BMI, total cholesterol of mild HT group decreased sign-ificantly(238.0 ± 24,7mg/dl vs217.9 ±28.2mg/dl, p < 0.05) , and HDL cholesterol of normatensive group increased significantly (63.2 ± 12.6mg/a vs 71.4 ± 12.9mg/dl, p < 0.01).
Conclusion: The present study suggests that swimming exercise can he useful for alt-eration in the function of vascular endothelial cells in hypertensive subjects.
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