2005 Fiscal Year Final Research Report Summary
Development of Reaction and Function Control Systems by Microchip Integration
| Project/Area Number |
13GS0024
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| Research Category |
Grant-in-Aid for Creative Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TAKEHIKO Kitamori The University of Tokyo, Graduate school of Engineering, Professor (60214821)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Shu The University of Tokyo, Graduate school of Pharmaceutical Science, Professor (50195781)
MATSUMOTO Kazuko Waseda University, Faculty of Science and Engineering, Professor (60111457)
SHOJI Shuichi Waseda University, Faculty of Science and Engineering, Professor (00171017)
UOZUMI Yasuhiro National Institutes of National Sciences, Institute of molecular science, Professor (90201954)
HISAMOTO Hideaki University of Hyogo, Faculty of Science, Assistant Professor (00286642)
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| Project Period (FY) |
2001 – 2005
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| Keywords | Microchip / Catalytic reaction / Macromolecular Metal Complexes / Micro machine / Organic synthesis / Micro reactor / Integrated chemistry |
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| Research Abstract |
Major purpose of the project is to create the new research field, microspace chemistry, by creating chemically functional microspace such as asymmetric catalyst, molecular harvesting, molecular recognition, and stimulate-responsive properties. Within a given period of this project, we exploited chemically functional microspace on a chip, highly functional matrices, and high performance analysis devices. Detailed information is as follows ;
(1) Development of micro liquid/liquid interface and synthesis of a chemicofunctional mebbrane.
(2) Development of the efficient catalyst for microscale synthesis and the nano-structured catalyst.
(3) Realization of various combinatorial synthesis chips.
(4) New reaction system using Gas-Liquid-Solid phase reactions in a microchannel (Ref. Science).
(5) Development of surface modification method in a microchannel and demonstration of fluid control of gas/liquid or liquid/liquid.
(6) Demonstration of asymmetric synthesis based on supercooling water.
(7) Development of high performance p-ELISA devices for medical diagnosis.
We published these results in high impact factor journals, and gave a lecture in various international conferences. Furthermore, these results can contribute to a variety of application in industrial circles.
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