Development of Detection Methods of Dynamical Higher Order Structures of Proteins and Its Application to Elucidation of Structure-Function Relations of Proteins.

2006 Fiscal Year Final Research Report Summary

• Project/Area Number: 14001004
• Research Category: Grant-in-Aid for Specially Promoted Research
• Allocation Type: Single-year Grants
• Review Section: Chemistry
• Research Institution: Institute Molecular Science (2006); National Institutes of Natural Sciences Okazaki Research Facilities (2004-2005); Okazaki National Research Institutes (2002-2003)
• Principal Investigator: KITAGAWA Teizo Institute for Molecular Science, Emeritus Professor, 名誉教授 (40029955)
• Co-Investigator(Kenkyū-buntansha): MIZUTANI Yasuhisa Osaka University, Graduate School of Science, Professor, 理学研究科, 教授 (60270469) ; UCHIDA Takeshi Hokkaido University, Faculty of Science, Assistant Professor, 理学研究科, 助教 (30343742)
• Project Period (FY): 2002 – 2006
• Keywords: Resonance Raman / Gas Sensor Heme Protein / Higher Order Structures / Ultraviolet Resonance Raman / FTIR Microscopy / Amvloid / Time-resolved Raman / Vibrational Spectroscopy

Research Abstract

Structural biology became a main subject in biophysical chemistry after the human genome problem, and 'Protein 3000' project has been successfully carried out. This project intended to uncover the protein structures with x-ray crystallography and NMR spectroscopy. Thus, the static structures of many proteins have been solved, but dynamical structures remained to be revealed to understand how proteins perform their functions. Our research aimed to provide more detailed structures of active sites of large proteins and also dynamical structures in their functioning state. For this purpose vibrational spectroscopy was adopted. New systems for obtaining time-resolved visible and ultraviolet resonance Raman spectra and microscope FTIR spectra were developed and applied to the following eights subjects; 1) Detection of ultrafast structural change of chromophores by using picosecond time-resolved visible resonance Raman spectroscopy, 2) Detection of fast changes of higher order structures of p roteins by using subnanosecond time-resolved ultraviolet resonance Raman spectroscopy, 3) Elucidation of the primary process in protein folding/unfolding by using laser temperature jump technique, 4) Development of a novel spectroscopy for functionally-important protein fluctuation, 5) Elucidation of the primary process in the light-induced DNA repair by DNA photolyases, 6) FTIR microspectroscopic investigation of amyloid fibril structures and a trigger mechanism along its formation, 7) Mechanism of sensing of environment and information transduction to a functional domain by gas sensor heme proteins, 8) Elucidation of mechanism of oxygen activation and proton active transport by heme enzymes. In practice we have constructed several inventive time-resolved resonance Raman systems, which cover a wide ranges of excitation wavelengths (from ultraviolet to near infrared) and time-resolution (from picosecond to second). We applied these systems successfully to basic proteins like hemoglobin and myoglobin and some new proteins like gas sensor proteins. We succeeded in elucidating mechanisms of target discrimination and information transmission in the gas sensor proteins.

Research Products

• [Journal Article] Synthesis and- Reactivity of (μ-η^2 : η^2-Peroxo)dicopper(II) Complexes with Dinucleating Ligands : Hydroxylation of Xylyl Linker with a NIH Shift (2007)
  • Author(s): Matsumoto, M.
  • Journal Title: J. Organomet. Chem. 692 Pages: 111-121
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Regioselective Arene Hydroxylation Mediated by a (μ-Peroxo)diiron(III) Complex : A Functional Model for Toluene Monooxygenase (2007)
  • Author(s): Yamashita, M.
  • Journal Title: J. Am. Chem. Soc. 129 Pages: 2-3
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Synthesis, Characterization, and Reactivities of Manganese(V)-Oxo Porphyrin Complexes (2007)
  • Author(s): Song, W. J.
  • Journal Title: J. Am. Chem. Soc. 129 Pages: 1268-1277
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Ultraviolet Resonance Raman Evidence for Utilization of the Heme 6-Propionate Hydrogen Bond Network in Signal Transmission from Heme to Protein in Ec DOS Protein (2007)
  • Author(s): El-Mashtoly, S. F.
  • Journal Title: J. Am. Chem. Soc 129 Pages: 3556-3563
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Unique Peroxidase Reaction Mechanism in Prostagladin Endoperoxide H Synthase-2 : CONPOUND I IN PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-2 CAN BE FORMED WITHOUT ASSISTANCE BY DISTAL GLUTAMINE RESIDUE (2007)
  • Author(s): Ichimura, S.
  • Journal Title: J. Biol. Chem. 282 Pages: 16681-16690
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Observation of the Structural Dynamics of FixL on signal Transduction and Ligand Discrimination (2007)
  • Author(s): Hiruma, Y.
  • Journal Title: Biochemistry 46 Pages: 6086-6096
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] 気体センサー蛋白質が特異的に気体分子を認識し、応答するメカニズム (2007)
  • Author(s): 内田 毅
  • Journal Title: 化学と工業 60 Pages: 222-223
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] シトクロムc翻訳後修飾タンパク質の機能と構造 (2007)
  • Author(s): 内田 毅
  • Journal Title: 生物物理 47 Pages: 112-117
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Primary protein response after ligand photodissociation in carbonmonoxy myoglobin (2007)
  • Author(s): Sato, A.
  • Journal Title: Proc. Natl.Acad. Sci. U.S.A. 104 Pages: 9627-9632
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Synthesis and Reactivity of (μ-η^2 : η^2-Peroxo)dicopper(II) Complexes with Dinucleating Ligands : Hydroxylation of Xylyl Linker with a NIH Shift (2007)
  • Author(s): Matsumoto, M., Furutachi, H., Nagatomo, S., Tosha, T., Fujinami, S., Kitagawa, T., Suzuki, M.
  • Journal Title: J. Organomet. Chem. 692 Pages: 111
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Regioselective Arene Hydroxylation Mediated by a (μ-Peroxo)diiron(III) Complex : A Functional Model for Toluene Monooxygenase (2007)
  • Author(s): Yamashita, M., Furutachi, H., Tosha, T., Fujinami, S., Saito, W., Maeda, Y., Takahashi, K., Tanaka, K., Kitagawa, T., Suzuki, M.
  • Journal Title: J. Am. Chem. Soc. 129 Pages: 2
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Synthesis, Characterization, and Reactivities of Manganese(V)-Oxo Porphyrin Complexes (2007)
  • Author(s): Song, W.J., Seo, M.S., George, S.D., Ohta, T., Song, R., Kang, M-J., Tosha, T., Kitagawa, T., Solomon, E.I., Nam, W.
  • Journal Title: J. Am. Chem. Soc. 129 Pages: 1268
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Ultraviolet Resonance Raman Evidence for Utilization of the Heme 6-Propionate Hydrogen Bond Network in Signal Transmission from Heme to Protein in Ec DOS Protein (2007)
  • Author(s): El-Mashtoly, S.F., Takahashi, H., Shimizu, T., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 129 Pages: 3556
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Unique Peroxidase Reaction Mechanism in Prostagladin Endoperoxide H Synthase-2 : CONPOUND I IN PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-2 CAN BE FORMED WITHOUT ASSISTANCE BY DISTAL GLUTAMINE RESIDUE (2007)
  • Author(s): Ichimura, S., Uchida, T., Taniguchi, S., Hira, S., Tosha, T., Morishima, I., Kitagawa, T., Ishimori, K.
  • Journal Title: J. Biol. Chem. 282 Pages: 16681
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Observation of the Structural Dynamics of FixL on signal Transduction and Ligand Discrimination (2007)
  • Author(s): Hiruma, Y., Kikuchi, A., Tanaka, A., Shiro, Y., Mizutani, Y.
  • Journal Title: Biochemistry 46 Pages: 6086
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Recognition and Response Mechanism of Gas-Sensor Hemoproteins (2007)
  • Author(s): Uchida, T.
  • Journal Title: Chem. Chemical Industry 60 Pages: 222
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structure and Function of Cytochrome c Maturation Proteins (2007)
  • Author(s): Uchida, T.
  • Journal Title: Seibutsubutsuri 47 Pages: 112
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Primary Protein Response after Ligand Photodissociation in Carbonmonoxy Myoglobin (2007)
  • Author(s): Sato, A., Gao, Y., Kitagawa, T., Mizutani, Y.
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. 104 Pages: 9627
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Evidence for Displacement of the C-Helix by CO Ligation and DNA Binding to CooA Revealed by UV Resonance Raman Spectroscopy (2006)
  • Author(s): Kubo, M.
  • Journal Title: J. Biol. Chem. 281 Pages: 11271-11278
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] On the Relationship of Coral Allene Oxide Synthase to Catalase : A Single Active Site Mutation That Induces Catalase Activity in Coral Allene Oxide Synthase (2006)
  • Author(s): Tosha, T.
  • Journal Title: J. Biol. Chem. 281 Pages: 12610-12617
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Pathway of Information Transmission from Heme to Protein upon Ligand Binding/Dissociation in Myoglobin Revealed by UV Resonance Raman Spectroscopy (2006)
  • Author(s): Gao, Y.
  • Journal Title: Biol. Chem. 281 Pages: 24637-24646
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Similarities and Differences between Cyclobutane Pyrimidine Dimer (CPD) Photolyase and (6-4) Photolyase as Revealed by Resonance Raman Spectroscopy : Electron Transfer from FAD Cofactor to UV-Damaged DNA (2006)
  • Author(s): Li, J.
  • Journal Title: J. Biol. Chem. 281 Pages: 25551-25559
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Discovery of a Reaction Intermediate of Aliphatic Aldoxime Dehydratase Involving Heme as an Active Center (2006)
  • Author(s): Konishi, K.
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. 103 Pages: 564-568
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Intramolecular Arene Hydroxylation versus Intermolecular Olefin Epoxidation by (μ-η^2 : η^2-Peroxo)dicopper(II) Complex Supported by Dinucleating Ligand (2006)
  • Author(s): Matsumoto, T.
  • Journal Title: J. Am. Chem Soc. 128 Pages: 3874-3875
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identification of an "End-on" Nickel-Superoxo Adduct, [Ni(tmc)(O_2)]^+ (2006)
  • Author(s): Kieber-Emmons, M. T.
  • Journal Title: J. Am. Chem. Soc. 128 Pages: 14230-14231
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Characterization of the Phenoxyl Radical in Model Complexes for the Cu_B Site of Cytochrome c Oxidase : Steady-State and Transient Absorption Measurements, UV Resonance Raman Spectroscopy, EPR Spectroscopy, and DFT Calculations for M^<II>-BIAIP (2006)
  • Author(s): Nagano, Y.
  • Journal Title: J. Am. Chem. Soc. 128 Pages: 14560-14570
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Sequential Reaction Intermediates in Aliphatic C-H Bond Functionalization Initiated by a Bis(μ-oxo)dinickel(III) Complex (2006)
  • Author(s): Cho. J.
  • Journal Title: Inorg. Chem. 45 Pages: 2873-2885
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Characterization of a Bimetallic-Bridging Intermediate in the Reduction of NO to N_2O : a Density Functional Theory Study (2006)
  • Author(s): Ohta, T.
  • Journal Title: Inorg Chem. 45 Pages: 3187-3190
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Significance of the Molecular Shape of Iron Corrphycene in a Protein Pocket (2006)
  • Author(s): Neya, S.
  • Journal Title: Inorg. Chem. 45 Pages: 4238-4242
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] ^<17>O NMR Study of Oxo Metalloporphyrin Complexes : Correlation with Electronic Structure of M=O Moiety (2006)
  • Author(s): Fujii, H.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 533-541
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Nonheme Iron(II) Complexes of Macrocyclic Ligands in the Generation of Oxoiron(IV) Complexes and the Catalytic Epoxidation of Olefins (2006)
  • Author(s): Suh, Y.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 627-633
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Enhancement of Fe^<IV>=O Stretch in High-Valent Iron Porphyrins : An Insight from TD-DFT Calculations (2006)
  • Author(s): Kozlowski, P. M.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 744-750
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Spectroscopic and Substrate Binding Properties of Heme-Containing Aldoxime Dehydratases, OxdB and OxdRE (2006)
  • Author(s): Kobayashi, K.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 1069-1074
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Raman Evidence for Specific Substrate-Induced Structural Changes in the Heme Pocket of Human Cytochrome P450 Aromatase during the Three Consecutive Oxygen Activation Steps (2006)
  • Author(s): Tosha, T.
  • Journal Title: Biochemistry 45 Pages: 5631-5640
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Specific Hydrogen-Bonding Networks Responsible for Selective O_2 Sensing of the Oxygen Sensor Protein HemAT from Bacillus subtilis (2006)
  • Author(s): Yoshimura, H.
  • Journal Title: Biochemistry 45 Pages: 8301-8307
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Spectroscopic and DNA-Binding Characterization of the Isolated Heme-Bound Basic Helix-loop-helix-PAS-A Domain of Neuronal PAS Protein 2 (NPAS2), a Transcription Activator Protein Associated with Circadian Rhythms (2006)
  • Author(s): Mukaiyama, Y.
  • Journal Title: FEBS J. 273 Pages: 2528-2539
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Characteristic Structure and Environment in FAD Cofactor of (6-4) Photolyase Along Function Revealed by Resonance Raman Spectroscopy (2006)
  • Author(s): Li, J.
  • Journal Title: J. Phys. Chem. B 110 Pages: 239-243
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Time-Resolved Raman Evidence for Energy Funneling through Propionate Side Chains in Heme Cooling upon Photolysis of Carbonmonoxy Myoglobin (2006)
  • Author(s): Gao, Y.
  • Journal Title: Chem. Phys. Lett. 429 Pages: 239-243
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structure of Interacting Segments in the Growing Amyloid Fibril of β_2-Microglobulin Probed with IR Spectroscopy (2006)
  • Author(s): Lu, M.
  • Journal Title: J. Mol. Biol. 362 Pages: 355-364
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Intersite Structural Rearrangement of the Blue Copper Site Induced by Substrate Binding : Spectroscopic Studies of a Copper-Containing Nitrite Reductase from Alcaligenes xylosoxidans NCIMB 11015 (2006)
  • Author(s): Kohzuma, T.
  • Journal Title: Inorg. Chem. 45 Pages: 8474-8476
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A Mononuclear Alkylperoxocopper(II) Complex as a Reaction Intermediate in the Oxidation of the Methyl Group of the Supporting Ligand (2006)
  • Author(s): Mizuno, M.
  • Journal Title: Angew. Chem. Int. Ed. 118 Pages: 6911-6914
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mononuclear Copper(II)-Hydroperoxo Complex Derived from Reaction of Copper(I) Complex with Dioxygen as a Model of DβM and PHM (2006)
  • Author(s): Fujii, T.
  • Journal Title: Chem. Commun. Pages: 4428-4430
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Systematic Regulation of the Enzymatic Activity of Phenylacetaldoxime Dehydratase by Exogenous Ligands (2006)
  • Author(s): Kobayashi, K.
  • Journal Title: ChemBioChem 7 Pages: 2004-2009
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Role of Heme Propionates of Myoglobin in Vibrational Energy Relaxation (2006)
  • Author(s): Koyama, M.
  • Journal Title: Chem. Phys. Lett. 430 Pages: 404-408
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Dynamic Ligation Properties of the Escherichia coli Heme Chaperone CcmE to Non-Covalently Bound Heme (2006)
  • Author(s): Stevens, J.M., Uchida, T., Daltrop, O., Kitagawa, T., Ferguson, S.J.
  • Journal Title: J. Biol. Chem. 281 Pages: 6144
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Evidence for Displacement of the C-Helix by CO Ligation and DNA Binding to CooA Revealed by UV Resonance Raman Spectroscopy (2006)
  • Author(s): Kubo, M., Inagaki, S., Yoshioka, S., Uchida, T., Mizutani, Y., Aono, S., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 281 Pages: 11271
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] On the Relationship of Coral Allene Oxide Synthase to Catalase : A Single Active Site Mutation That Induces Catalase Activity in Coral Allene Oxide Synthase (2006)
  • Author(s): Tosha, T., Uchida, T., Brash, A.R., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 281 Pages: 12610
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Pathway of Information Transmission from Heme to Protein upon Ligand Binding/Dissociation in Myoglobin Revealed by UV Resonance Raman Spectroscopy (2006)
  • Author(s): Gao, Y., El-Mashtoly, S.F., Pal, B., Hayashi, T., Harada, K., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 281 Pages: 24637
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Similarities and Differences between Cyclobutane Pyrimidine Dimer (CPD) Photolyase and (6-4) Photolyase as Revealed by Resonance Raman Spectroscopy : Electron Transfer from FAD Cofactor to UV-Damaged DNA (2006)
  • Author(s): Li, J., Uchida, T., Todo, T., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 281 Pages: 25551
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Discovery of a Reaction Intermediate of Aliphatic Aldoxime Dehydratase Involving Heme as an Active Center (2006)
  • Author(s): Konishi, K., Ohta, T., Oinuma, K., Hashimoto, Y., Kitagawa, T., Kobayashi, M.
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. 103 Pages: 564
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Intramolecular Arene Hydroxylation versus Intermolecular Olefin Epoxidation by (μ-η^2 : η^2-Peroxo)dicopper(II) Complex Supported by Dinucleating Ligand", J. Am. Chem Soc., 128, 3874 (2006). (2006)
  • Author(s): Matsumoto, T., Furutachi, H., Kobino, M., Tomii, M., Nagatomo, S., Tosha, T., Osako, T., Fujinami, S., Itoh, S., Kitagawa, T., Suzuki, M.
  • Journal Title: J. Am. Chem Soc. 128 Pages: 3874
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Identification of an End-on Nickel-Superoxo Adduct, [Ni(tmc)(O_2)]+ (2006)
  • Author(s): Kieber-Emmons, M.T., Annaraj, J., Seo, M.S., Van Heuvelen, K.M., Tosha, T., Kitagawa, T., Brunold, T.C., Nam, W., Riordan, C.G.
  • Journal Title: J. Am. Chem. Soc. 128 Pages: 14230
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characterization of the Phenoxyl Radical in Model Complexes for the Cu_B Site of Cytochrome c Oxidase : Steady-State and Transient Absorption Measurements, UV Resonance Raman Spectroscopy, EPR Spectroscopy, and DFT Calculations for MII-BIAIP (2006)
  • Author(s): Nagano, Y., Liu, J.-G., Naruta, Y., Ikoma, T., Tero-Kubota, S., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 128 Pages: 14560
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Sequential Reaction Intermediates in Aliphatic C-H Bond Functionalization Initiated by a Bis(μ-oxo)dinickel(III) Complex (2006)
  • Author(s): Cho.J., Furutachi, H., Fujinami, S., Tosha, T., Ohtsu, H., Ikeda, O., Suzuki, A., Nomura, M., Uruga, T., Tanida, H., Kawai, T., Tanaka, K., Kitagawa, T., Suzuki, M.
  • Journal Title: Inorg. Chem. 45 Pages: 2873
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characterization of a Bimetallic-Bridging Intermediate in the Reduction of NO to _2O : a Density Functional Theory Study (2006)
  • Author(s): Ohta, T., Kitagawa, T., Varotsis, C.
  • Journal Title: Inorg Chem. 45 Pages: 3187
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Significance of the Molecular Shape of Iron Corrphycene in a Protein Pocket (2006)
  • Author(s): Neya, S., Imai, K., Hiramatsu, Y., Kitagawa, T., Hoshino, T., Hata, M., Funasaki, N.
  • Journal Title: Inorg. Chem. 45 Pages: 4238
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] ^<17>O NMR Study of Oxo Metalloporphyrin Complexes : Correlation with Electronic Structure of M=O Moiety (2006)
  • Author(s): Fujii, H., Kurahashi, T., Tosha, T., Yoshimura, T., Kitagawa, T.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 533
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Nonheme Iron(II) Complexes of Macrocyclic Ligands in the Generation of Oxoiron(IV) Complexes and the Catalytic Epoxidation of Olefins (2006)
  • Author(s): Suh, Y., Seo, M.S., Kim, K.M., Kim, Y.S., Jang, H.G., Tosha, T., Kitagawa, T., Kim, J., Nam, W.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 627
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Enhancement of FeIV=O Stretch in High-Valent Iron Porphyrins : An Insight from TD-DFT Calculations (2006)
  • Author(s): Kozlowski, P.M., Kutta, J., Ohta, T., Kitagawa, T.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 744
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Spectroscopic and Substrate Binding Properties of Heme-Containing Aldoxime Dehydratases, OxdB and OxdRE (2006)
  • Author(s): Kobayashi, K., Pal, B., Yoshioka, S., Kato, Y., Asano, Y., Kitagawa, T., Aono, S.
  • Journal Title: J. Inorg. Biochem. 100 Pages: 1069
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Raman Evidence for Specific Substrate-Induced Structural Changes in the Heme Pocket of Human Cytochrome P450 Aromatase during the Three Consecutive Oxygen Activation Steps (2006)
  • Author(s): Tosha, T., Kagawa, N., Ohta, T., Yoshioka, S., Waterman, M.R., Kitagawa, T.
  • Journal Title: Biochemistry 45 Pages: 5631
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Specific Hydrogen-Bonding Networks Responsible for Selective O_2 Sensing of the Oxygen Sensor Protein HemAT from Bacillus subtilis (2006)
  • Author(s): Yoshimura, H., Yoshioka, S., Kobayashi, K., Ohta, T., Uchida, T., Kubo, M., Kitagawa, T., Aono, S.
  • Journal Title: Biochemistry 45 Pages: 8301
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Spectroscopic and DNA-Binding Characterization of the Isolated Heme-Bound Basic Helix-loop-helix-PAS-A Domain of Neuronal PAS Protein 2 (NPAS2), a Transcription Activator Protein Associated with Circadian Rhythms (2006)
  • Author(s): Mukaiyama, Y., Uchida, T., Sato, E., Sasaki, A., Sato, Y., Igarashi, J., Kurokawa, H., Sagami, I., Kitagawa, T., Shimizu, T.
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  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characteristic Structure and Environment in FAD Cofactor of (6-4) Photolyase Along Function Revealed by Resonance Raman Spectroscopy (2006)
  • Author(s): Li, J., Uchida, T., Ohta, T., Todo, T., Kitagawa, T.
  • Journal Title: J. Phys. Chem. B 110 Pages: 16724
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Time-Resolved Raman Evidence for Energy Funneling through Propionate Side Chains in Heme Cooling upon Photolysis of Carbonmonoxy Myoglobin (2006)
  • Author(s): Gao, Y., Koyama, M., El-Mashtoly, S.F., Hayashi, T., Harada, K., Mizutani, Y., Kitagawa, T.
  • Journal Title: Chem. Phys. Lett. 429 Pages: 239
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Role of Heme Propionates of Myoglobin in Vibrational Energy Relaxation (2006)
  • Author(s): Koyama, M., Neya, S., Mizutani, Y.
  • Journal Title: Chem. Phys. Lett. 430 Pages: 404
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structure of Interacting Segments in the Growing Amyloid Fibril of β_2-Microglobulin Probed with IR Spectroscopy (2006)
  • Author(s): Lu, M., Hiramatsu, H., Goto, Y., Kitagawa, T.
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  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Intersite Structural Rearrangement of the Blue Copper Site Induced by Substrate Binding : Spectroscopic Studies of a Copper-Containing Nitrite Reductase from Alcaligenes xylosoxidans NCIMB 11015 (2006)
  • Author(s): Kohzuma, T., Kikuchi, M., Horikoshi, N., Nagatomo, S., Kitagawa, T., Czernuszewicz, R.S.
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  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A Mononuclear Alkylperoxocopper(II) Complex as a Reaction Intermediate in the Oxidation of the Methyl Group of the Supporting Ligand (2006)
  • Author(s): Mizuno, M., Honda, K., Cho, J., Furutachi, H., Tosha, T., Matsumoto, T., Fujinami, S., Kitagawa, T., Suzuki, M.
  • Journal Title: Angew. Chem. Int. Ed. 118 Pages: 7065
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Mononuclear Copper(II)-Hydroperoxo Complex Derived from Reaction of Copper(I) Complex with Dioxygen as a Model of D M and PHM (2006)
  • Author(s): Fujii, T., Yamaguchi, S., Funahashi, Y., Ozawa, T., Tosha, T., Kitagawa, T., Masuda, H.
  • Journal Title: Chem. Commun. Pages: 4428
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Systematic Regulation of the Enzymatic Activity of Phenylacetaldoxime Dehydratase by Exogenous Ligands (2006)
  • Author(s): Kobayashi, K., Kubo, M., Yoshioka, S., Kitagawa, T., Kato, Y., Asano, Y., Aono, S.
  • Journal Title: Chem. Bio. Chem. 7 Pages: 2004
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Physical Chemistry for the Biosciences" (Raymond Chang) (2006)
  • Author(s): Iwasawa, Y., Kitagawa, T., Hamaguchi, H.
  • Journal Title: Tokyo Kagaku Dozin Co., Ltd.
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Interactions of Soluble Guanylate Cyclase with Diatomics as Probed by Resonance Raman Spectroscopy (2005)
  • Author(s): Pal, B.
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  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Mechanism for Transduction of the Ligand-Binding Signal in Heme-Based Gas Sensory Proteins Reavealed by Resonance Raman Spectroscopy (2005)
  • Author(s): Uchida, T.
  • Journal Title: Acc. Chem. Res. 38 Pages: 662-670
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Investigation on the Specific Sensing Mechanism of a Target Molecule by Gas Sensory Proteins (2005)
  • Author(s): Ohta, T.
  • Journal Title: Inorg. Chem. 44 Pages: 758-769
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Oxidizing Intermediates from the Sterically Hindered Iron Salen Complexes Related to the Oxygen Activation by Nonheme Iron Enzymes (2005)
  • Author(s): Kurahashi, T.
  • Journal Title: Inorg. Chem. 44 Pages: 8156-8166
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural Studies Reveal That the Diverse Morphology of β_2-microglobulin Aggregates Is a Reflection of Different Molecular Architectures (2005)
  • Author(s): Kardos, J.
  • Journal Title: Biochim Biophys Acta. 1753 Pages: 108-120
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] FT-IR Approaches on Amyloid Fibril Structure (2005)
  • Author(s): Hiramatsu, H.
  • Journal Title: Biochem. Biophys. Acta. 1753 Pages: 100-107
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Evidence for the Presence of Two Heme Pocket Conformations with Varied Activities in CO-Bound Bovine Soluble Guanylate Cyclase and Their Conversion (2005)
  • Author(s): Li, Z. Q.
  • Journal Title: Biochemistry 44 Pages: 939-946
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural Characterization of the Proximal and Distal Histidine Environment of Cytoglobin and Neuroglobin (2005)
  • Author(s): Sawai, H.
  • Journal Title: Biochemistry 44 Pages: 13257-13265
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Biophysical Properties of a c-Type Heme in Chemotaxis Signal Transducer Protein DcrA. (2005)
  • Author(s): Yoshioka, S.
  • Journal Title: Biochemistry 44 Pages: 15406-15413
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Quaternary Structures of Intermediately Ligated Hemoglobin and Influences from Strong Allosteric Effectors; Resonance Raman Investigation (2005)
  • Author(s): Nagatomo, S.
  • Journal Title: Biophys. J 89 Pages: 1203-1213
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Spectroscopic and Redox Properties of a CooA Homologue from Carboxydothermus hydrogenoformans (2005)
  • Author(s): Inagaki, S.
  • Journal Title: J. Biol. Chem. 280 Pages: 3269-3274
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural Diversities of Active Site in Clinical Azole-Bound Forms between Sterol 14α-Demethylases (CYP51s) from Human and Mycobacterium tuberculosis (2005)
  • Author(s): Matsuura, K.
  • Journal Title: J. Biol. Chem. 280 Pages: 9088-9096
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] CO-Dependent Activity-Controlling Mechanism of Heme-Containing CO-Sensor Protein, Neuronal PAS Domain Protein 2 (2005)
  • Author(s): Uchida, T.
  • Journal Title: J. Biol. Chem. 280 Pages: 21358-21368
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] UV Resonance Raman Study of Model Complexes of the Cu_B Site of Cytochrome c Oxidase (2005)
  • Author(s): Nagano, Y.
  • Journal Title: J. Mol. Struct. 279 Pages: 735-736
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural and Spectroscopic Characterization of (μ-Hydroxo or μ-Oxo)(μ-peroxo)diiron(III) Complexes; Model for Peroxo Intermediates of Non-Heme Diiron Proteins (2005)
  • Author(s): Zhang, X.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 826-827
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Reversible O-O Bond Cleavage and Formation of a Peroxo Moiety of Peroxocabonate Ligand Performed by an Iron(III) Complex (2005)
  • Author(s): Furutachi, H.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 4550-4551
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Synthesis and Reactivity of a (μ-1,1-Hydroperoxo)(μ-hydroxo)dicopper(II) Complex : Ligand Hydroxylation by a Bridging Hydroperoxo Ligand (2005)
  • Author(s): Itoh, K.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 5212-5223
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural Model of the Amyloid Fibril Formed by β_2-Microglobulin #21-31 Fragment Based on Vibrational Spectroscopy (2005)
  • Author(s): Hiramatsu, H.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 7988-7989
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Energy Funneling of IR Photons Captured by Dendritic Antennae and Acceptor Mode Specificity : Anti-Stokes Resonance Raman Studies on Iron(III)-Porphyrin Complexes with a Poly(aryl ether) Dendrimer Framework (2005)
  • Author(s): Mo, Y.-J.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 10020-10027
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Axial Ligand Substituted Nonheme Fe^<IV>=O Complexes : Observation of New Near-UV LMCT bands and Fe=O Raman Vibrations (2005)
  • Author(s): Sastri, C. V.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 12494-12495
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Detection of the His-Heme Fe^<2+>-NO Species in the Reduction of NO to N_2O by bα_3-Oxidase from Thermus thermophilus (2005)
  • Author(s): Pinakoulaki, E.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 15161-15167
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Stopped-Flow Spectrophotometric and Resonance Raman Analyses of Aldoxime Dehydratase Involved in Carbon-Nitrogen Triple Bond Synthesis (2005)
  • Author(s): Oinuma, K.
  • Journal Title: FEBS Lett. 579 Pages: 1394-1398
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Spectroscopic Characterization of the Isolated Heme-Bound PAS-B Domain of Neuronal PAS Domain Protein 2 (NPAS2) Associated with Circadian Rhythms (2005)
  • Author(s): Koudo, R.
  • Journal Title: FEBS J. 272 Pages: 4153-4162
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Synthesis, Characterization, and Thermal Stability of New Mononuclear Hydrogenperoxocopper(II) Complexes with N_3O-Type Tripodal Ligands Bearing Hydrogen-Bonding Interaction Sites (2005)
  • Author(s): Yamaguchi, S.
  • Journal Title: Bull. Chem. Soc. Jpn 78 Pages: 116-124
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Excited State Property of Hardly Photodissociable Heme-CO Adduct Studied by Time-Dependent Density Functional Theory (2005)
  • Author(s): Ohta, T.
  • Journal Title: J. Phys. Chem. B 109 Pages: 21110-21117
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structure and Dioxygen-Reactivity of Copper(I) Complexes Supported by Bis(6-Methylpyridin-2-yl-methyl)amine Tridentate Ligands (2005)
  • Author(s): Osako, T.
  • Journal Title: Dalton Trans. Pages: 3514-3521
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Kinetics and DFT studies on the reaction of copper(II) complexes and H_2O_2 (2005)
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  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Isotope Dilution Effects on the Hydroxyl Stretch Bands of Alcohols (2005)
  • Author(s): Uemura T.
  • Journal Title: Mol. Phys. 103 Pages: 37-44
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Picosecond Structural Dynamics of Myoglobin Following Photodissociation of Carbon Monoxide as Revealed by Ultraviolet Time-Resolved Resonance Raman Spectroscopy (2005)
  • Author(s): Sato A.
  • Journal Title: Biochemistry 44 Pages: 14709-14714
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Covalent Cofactor Attachment to Proteins : Cytochrome c Biogenesis (2005)
  • Author(s): Stevens, J. M.
  • Journal Title: Biochem. Soc. Trans. 33 Pages: 792-795
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] チトクロムcの合成におけるヘムシャペロン(CcmE)の役割 (2005)
  • Author(s): 内田 毅
  • Journal Title: 化学と工業 58 Pages: 503
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Interactions of Soluble Guanylate Cyclase with Diatomics as Probed by Resonance Raman Spectroscopy (2005)
  • Author(s): Pal, B., Kitagawa, T.
  • Journal Title: J. Inorg. Biochem. 99 Pages: 267
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Mechanism for Transduction of the Ligand-Binding Signal in Heme-Based Gas Sensory Proteins Reavealed by Resonance Raman Spectroscopy (2005)
  • Author(s): Uchida, T., Kitagawa, T.
  • Journal Title: Acc. Chem. Res. 38 Pages: 662
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Isotope Dilution Effects on the Hydroxyl Stretch Bands of Alcohols (2005)
  • Author(s): Uemura T., Saito S., Mizutani Y., Tominaga K.
  • Journal Title: Mol. Phys. 103 Pages: 37
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Investigation on the Specific Sensing Mechanism of a Target Molecule by Gas Sensory Proteins (2005)
  • Author(s): Ohta, T., Kitagawa, T.
  • Journal Title: Inorg. Chem. 44 Pages: 758
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Oxidizing Intermediates from the Sterically Hindered Iron Salen Complexes Related to the Oxygen Activation by Nonheme Iron Enzymes (2005)
  • Author(s): Kurahashi, T., Kobayashi, Y., Nagatomo, S., Tosha, T., Kitagawa, T., Fujii, H.
  • Journal Title: Inorg. Chem. 44 Pages: 8156
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Studies Reveal That the Diverse Morphology of β2-microglobulin Aggregates Is a Reflection of Different Molecular Architectures (2005)
  • Author(s): Kardos, J., Okuno, D., Kawai, T., Hagihara, Y., Yumoto, N., Kitagawa, T., Zavodszky, P., Naiki, H., Goto, Y.
  • Journal Title: Biochim Biophys Acta 1753 Pages: 108
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] FT-IR Approaches on Amyloid Fibril Structure (2005)
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  • Journal Title: Biochem. Biophys. Acta 1753 Pages: 100
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Evidence for the Presence of Two Heme Pocket Conformations with Varied Activities in CO-Bound Bovine Soluble Guanylate Cyclase and Their Conversion (2005)
  • Author(s): Li, Z.Q., Pal, B., Takenaka, S., Tsuyama, S., Kitagawa, T.
  • Journal Title: Biochemistry 44 Pages: 939
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Characterization of the Proximal and Distal Histidine Environment of Cytoglobin and Neuroglobin (2005)
  • Author(s): Sawai, H., Makino, M., Mizutani, Y., Ohta, T., Sugimoto, H., Uno, T., Kawada, N., Yoshizato, K., Kitagawa, T., Shiro, Y.
  • Journal Title: Biochemistry 44 Pages: 13257
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Picosecond Structural Dynamics of Myoglobin Following Photodissociation of Carbon Monoxide as Revealed by Ultraviolet Time-Resolved Resonance Raman Spectroscopy (2005)
  • Author(s): Sato A., Mizutani Y.
  • Journal Title: Biochemistry 44 Pages: 14709
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Unique Structural Properties of a Chemotaxis Signal Transducer Protein DcrA Containing a c-Type Heme (2005)
  • Author(s): Yoshioka, S., Kobayashi, K., Uchida, T., Kitagawa, T., Aono, S.
  • Journal Title: Biochemistry 44 Pages: 15406
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Quaternary Structures of Intermediately Ligated Hemoglobin and Influences from Strong Allosteric Effectors; Resonance Raman Investigation (2005)
  • Author(s): Nagatomo, S., Nagai, M., Mizutani, Y., Yonetani, T., Kitagawa, T.
  • Journal Title: Biophys. J. 89 Pages: 1203
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Spectroscopic and Redox Properties of a CooA Homologue from Carboxydothermus hydrogencformans (2005)
  • Author(s): Inagaki, S., Masuda, C., Akaishi, T., Nakajima, H., Yoshioka, S., Ohta, T., Pal, B., Kitagawa, T., Aono, S.
  • Journal Title: J. Biol. Chem. 280 Pages: 3269
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Diversities of Active Site in Clinical Azole-Bound Forms between Sterol 14α-Demethylases (CYP51s) from Human and Mycobacterium tuberculosis (2005)
  • Author(s): Matsuura, K., Shiro, Y., Tosha, T., Hori, H., Ishimori, K., Kitagawa, T., Morishima, I., Kagawa, N., Waterman, M.R.
  • Journal Title: J. Biol. Chem. 280 Pages: 9088
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] CO-Dependent Activity-Controlling Mechanism of Heme-Containing CO-Sensor Protein, Neuronal PAS Domain Protein 2 (2005)
  • Author(s): Uchida, T., Sato, E., Sato, A., Sagami, I., Shimizu, T., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 280 Pages: 21358
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] UV Resonance Raman Study of Model Complexes of the Cu_B Site of Cytochrome c Oxidase (2005)
  • Author(s): Nagano, Y., Liu, J.-G., Naruta, Y., Kitagawa, T.
  • Journal Title: J. Mol. Struct. 279 Pages: 735
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural and Spectroscopic Characterization of (μ-Hydroxo or μ-Oxo)(μ-peroxo)diiron(III) Complexes; Model for Peroxo Intermediates of Non-Heme Diiron Proteins (2005)
  • Author(s): Zhang, X., Furutachi, H., Fujinami, S., Nagatomo, S., Maeda, Y., Watanabe, Y., Kitagawa, T., Suzuki, M.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 826
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Reversible O-O Bond Cleavage and Formation of a Peroxo Moiety of Peroxocabonate Ligand Performed by an Iron(III) Complex", J. Am. Chem. Soc., 127, 4550 (2005). (2005)
  • Author(s): Furutachi, H., Hashimoto, K., Nagatomo, S., Endo, T., Fujinami, S., Watanabe, Y., Kitagawa, T., Suzuki, M.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 4550
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Synthesis and Reactivity of a (μ-1,1-Hydroperoxo)(μ-hydroxo)dicopper(II) Complex : Ligand Hydroxylation by a Bridging Hydroperoxo Ligand (2005)
  • Author(s): Itoh, K., Hayashi, H., Furutachi, H., Matsumoto, T., Nagatomo, S., Tosha, T., Terada, S., Fujinami, S., Suzuki, M., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 5212
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Model of the Amyloid Fibril Formed by β_2-Microglobulin #21-31 Fragment Based on Vibrational Spectroscopy (2005)
  • Author(s): Hiramatsu, H., Goto, Y., Naiki, H., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 7988
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Energy Funneling of IR Photons Captured by Dendritic Antennae and Acceptor Mode Specificity : Anti-Stokes Resonance Raman Studies on Iron(III)-Porphyrin Complexes with a Poly(aryl ether) Dendrimer Framework (2005)
  • Author(s): Mo, Y.-J., Jiang, D.-L., Uyemura, M., Aida, T., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 10020
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Axial Ligand Substituted Nonheme Fe^<IV>=O Complexes : Observation of New Near-UV LMCT bands and Fe=O Raman Vibrations (2005)
  • Author(s): Sastri, C.V., Park, M.J., Ohta, T., Jackson, T.A., Stubna, A., Seo, M.S., Lee, J., Kim, J., Kitagawa, T., Munck, E., Que, L.Jr., Nam, W.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 12494
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Detection of the His-Heme Fe^<2+>-NO Species in the Reduction of NO to N_2O by ba_3-Oxidase from Thermus thermophilus (2005)
  • Author(s): Pinakoulaki, E., Ohta, T., Soulimane, T., Kitagawa, T., Varotsis, C.
  • Journal Title: J. Am. Chem. Soc. 127 Pages: 15161
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Stopped-Flow Spectrophotometric and Resonance Raman Analyses of Aldoxime Dehydratase Involved in Carbon-Nitrogen Triple Bond Synthesis (2005)
  • Author(s): Oinuma, K., Kumita, H., Ohta, T., Konishi, K., Y.Hashimoto, Higashibata, H., Kitagawa, T., Shiro, Y., Kobayashi, M.
  • Journal Title: FEBS Lett. 579 Pages: 1394
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Spectroscopic Characterization of the Isolated Heme-Bound PAS-B Domain of Neuronal PAS Domain Protein 2 (NPAS2) Associated with Circadian Rhythms (2005)
  • Author(s): Koudo, R., Kurokawa, H., Sato, E., Igarashi, J., Uchida, T., Sagami, I., Kitagawa, T., Shimizu, T.
  • Journal Title: FEBS J. 272 Pages: 4153
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Synthesis, Characterization, and Thermal Stability of New Mononuclear Hydrogenperoxocopper(II) Complexes with N3O-Type Tripodal Ligands Bearing Hydrogen-Bonding Interaction Sites (2005)
  • Author(s): Yamaguchi, S., Kumagai, A., Nagatomo, S., Kitagawa, T., Funahashi, Y., Ozawa, T., Jitsukawa, K., Masuda, H.
  • Journal Title: Bull. Chem. Soc. Jpn 78 Pages: 116
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Excited State Property of Hardly Photodissociable Heme-CO Adduct Studied by Time-Dependent Density Functional Theory (2005)
  • Author(s): Ohta, T., Pal, B., Kitagawa, T.
  • Journal Title: J. Phys. Chem. B 109 Pages: 21110
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structure and Dioxygen-Reactivity of Copper(I) Complexes Supported by Bis(6-Methylpyridin-2-yl-methyl)amine Tridentate Ligands (2005)
  • Author(s): Osako, T., Terada, S., Tosha, T., Nagatomo, S., Furutachi, H., Fujinami, S., Kitagawa, T., Suzuki, M., Itoh, S.
  • Journal Title: Dalton Trans. Pages: 3514
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Kinetics and DFT studies on the reaction of copper(II) complexes and H_2O_2 (2005)
  • Author(s): Osako, T., Nagatomo, S., Kitagawa, T., Cramer, C.J., Itoh, S.
  • Journal Title: J. Biol. Inorg. Chem. 10 Pages: 581
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Covalent Cofactor Attachment to Proteins : Cytochrome c Biogenesis (2005)
  • Author(s): Stevens, J.M., Uchida, T., Daltrop, O., Ferguson, S.J.
  • Journal Title: Biochem. Soc. Trans. 33 Pages: 792
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The Role of Heme Chaperone Protein, CcmE, in Biosynthesis of Heme (2005)
  • Author(s): Uchida, T.
  • Journal Title: Chem. Chemical Industry 58 Pages: 503
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Raman Spectroscopy" Frontiers in Optical Science (2005)
  • Author(s): Uchida, T.
  • Journal Title: Japan Intense Light Field Science Society Pages: 96
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Characterization of a Binuclear Center of a Cu-Containing NO Reductase Homologue from Roseobacter denitrificans : EPR and Resonance Raman Studies (2004)
  • Author(s): Matsuda, Y.
  • Journal Title: Biochim. Biophys. Acta. 1656 Pages: 37-45
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Dinuclear Copper-Dioxygen Intermediates Supported by Polyamine Liaands (2004)
  • Author(s): Teramae, S.
  • Journal Title: J. Inorg. Biochem. 98 Pages: 746-757
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Study on Synergistic Activation of Soluble Guanylate Cyclase by Imidazole, YC-1 and GTP (2004)
  • Author(s): Pal, B.
  • Journal Title: J. Inorg. Biochem. 98 Pages: 824-832
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Activation of Heme-Regulated Eukaryotic Initiation Factor 2α Kinase (HRI) Activation by Nitric Oxide is Induced by the Formation of a Five-Coordinate NO-Heme Complex : Optical Absorption, Electron Spin Resonance and Resonance Raman Spectral Studies (2004)
  • Author(s): Igarashi, J.
  • Journal Title: J. Biol. Chem. 279 Pages: 15752-15762
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Simultaneous Resonance Raman Detection of the Heme a_3-Fe-CO and Cu_B-CO Species in CO-Bound ba_3-Cytochrome c Oxidase from Thermus thermophilus (2004)
  • Author(s): Pinakoulaki, E.
  • Journal Title: J. Biol. Chem. 279 Pages: 22791-22794
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Refolding Processes of Cytochrome P450_<cam> from Ferric and Ferrous Acid Forms to the Native Conformation (2004)
  • Author(s): Egawa, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 32008-32017
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Identification of Crucial Histidines Involved in Carbon-Nitrogen Triple Bond Synthesis by Aldoxime Dehydratase (2004)
  • Author(s): Konishi, K.
  • Journal Title: J. Biol. Chem. 279 Pages: 47619-47625
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] The Interaction of Covalently Bound Heme with the Cytochrome c Maturation Protein CcmE (2004)
  • Author(s): Uchida, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 51981
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Role of Tyr-288 at the Dioxygen Reduction Site of Cytochrome bo Studied by Stable Isotope Labeling and Resonance Raman Spectroscopy (2004)
  • Author(s): Uchida, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 53613-53620
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Core Structure of Amyloid Fibril Proposed from IR-Microscope Linear Dichroism (2004)
  • Author(s): Hiramatsu, H.
  • Journal Title: J. Am. Chem. Soc. 126 Pages: 3008-3008
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Oxygen Sensing Mechanism of HemAT from Bacillus subtilis : A Resonance Raman Spectroscopic Study (2004)
  • Author(s): Ohta, T.
  • Journal Title: J. Am. Chem. Soc. 126 Pages: 15000-15001
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Dioxygen Reactivity of Copper(I) Complexes with Retradentate Tripodal Ligands Having Apliphatic Nitrogen Donors : Synthesis, Structures, and Properties of Peroxo and Superoxo Complexes (2004)
  • Author(s): Komiyama, K.
  • Journal Title: Bull. Chem. Soc. Jpn 77 Pages: 59-72
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Heme Structures of Five Variants of Hemoglobin M Probed by Resonance Raman Spectroscopy (2004)
  • Author(s): Jin, Y.
  • Journal Title: Biochemistry 43 Pages: 8517-8527
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] SOUL in Mouse Eyes is a Novel Hexameric Heme-Binding Protein with Characteristic Optical Absorption, Resonance Raman Spectral and Heme Binding Properties (2004)
  • Author(s): Sato, E.
  • Journal Title: Biochemstry 43 Pages: 14189-14198
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Vibronic Coupling between Soret and Higher Energy Excited States in Iron(II) Porphyrins : Raman Excitation Profiles of A_<2g> Modes in the Soret Region (2004)
  • Author(s): Egawa, T.
  • Journal Title: J. Phys. Chem. A, 108 Pages: 568-577
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Detection of a Photostable Five-Coordinate Heme a_3-Fe-CO Species and Functional Implications of His384/α10 in CO-Bound ba_3-Cytochrome c Oxidase from Thermus thermophilus (2004)
  • Author(s): Ohta, T.
  • Journal Title: J. Phys. Chem. B 108 Pages: 5489-5491
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Model Complexes of the Active Site of Galactose Oxidase. Effects of the Metal Ion Binding Sites (2004)
  • Author(s): Taki, M.
  • Journal Title: Inorg. Chim. Acta 357 Pages: 3369-3381
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Heme Environment in Aldoxime Dehydratase Involved in Carbon-Nitrogen Triple Bond Synthesis (2004)
  • Author(s): Oinuma, K.
  • Journal Title: FEBS Lett 568 Pages: 44-48
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Steric and Hydrogen-Bonding Effects on the Stability of Copper Complexes with Small Molecules (2004)
  • Author(s): Wada, A.
  • Journal Title: Inorg. Chem. 43 Pages: 5725-5735
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Thermal Stability of Mononuclear Hydroperoxocopper(II) Species. Effects of Hydrogen Bonding and Hydrophobic Field (2004)
  • Author(s): Yamaguchi, S.
  • Journal Title: Chem. Lett. 33 Pages: 1556-1557
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman and Ligand-Binding Analysis of the Oxygen-Sensing Signal Transducer Protein HemAT from Bacillus subtilis (2004)
  • Author(s): Aono, S.
  • Journal Title: Methods Enzymol 381 Pages: 618-628
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] タンパク質の構造揺らぎと反応の相関-実験的研究法 (2004)
  • Author(s): 水谷 泰久
  • Journal Title: 生物物理 44 Pages: 222-225
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Characterization of the P Intermediate in the Reaction of Bovine Cytochrome c Oxidase (2004)
  • Author(s): Ogura, T., Kitagawa, T.
  • Journal Title: Biochim. Biophys. Acta 1655 Pages: 290
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural Characterization of a Binuclear Center of a Cu-Containing NO Reductase Homologue from Roseobacter denitrificans : EPR and Resonance Raman Studies (2004)
  • Author(s): Matsuda, Y., Uchida, T., Hori, H., Kitagawa, T., Arata, H.
  • Journal Title: Biochim. Biophys. Acta 1656 Pages: 37
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Dinuclear Copper-Dioxygen Intermediates Supported by Polyamine Ligands (2004)
  • Author(s): Teramae, S., Osako, T., Nagatomo, S., Kitagawa, T., Fukuzumi, S., Itoh, S.
  • Journal Title: J. Inorg. Biochem. 98 Pages: 746
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Study on Synergistic Activation of Soluble Guanylate Cyclase by Imidazole, YC-1 and GTP (2004)
  • Author(s): Pal, B., Li, Z., Ohta, T., Takenaka, S., Tsuyama, S., Kitagawa, T.
  • Journal Title: J. Inorg. Biochem. 98 Pages: 824
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Activation of Heme-Regulated Eukaryotic Initiation Factor 2α Kinase (HRI) Activation by Nitric Oxide is Induced by the Formation of a Five-Coordinate NO-Heme Complex : Optical Absorption, Electron Spin Resonance and Resonance Raman Spectral Studies (2004)
  • Author(s): Igarashi, J., Sato, A., Kitagawa, T., Yoshimura, T., Yamauchi, S., Sagami, I., Shimizu, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 15752
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Simultaneous Resonance Raman Detection of the Heme a_3-Fe-CO and Cu_B-CO Species in CO-Bound bα_3-Cytochrome c Oxidase from Thermus thermophilus (2004)
  • Author(s): Pinakoulaki, E., Ohta, T., Soulimane, T., Kitagawa, T., Varotsis, C.
  • Journal Title: J. Biol. Chem. 279 Pages: 22791
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Refolding Processes of Cytochrome P450_<cam> from Ferric and Ferrous Acid Forms to the Native Conformation (2004)
  • Author(s): Egawa, T., Hishiki, T., Ichikawa, Y., Kanamori, Y., Shimada, H., Takahashi, S., Kitagawa, T., Ishimura, Y.
  • Journal Title: J. Biol. Chem. 279 Pages: 32008
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Identification of Crucial Histidines Involved in Carbon-Nitrogen Triple Bond Synthesis by Aldoxime Dehydratase (2004)
  • Author(s): Konishi, K., Ishida, K., Oinuma, K., Ohta, T., Hashimoto, Y., Higashibata, H., Kitagawa, T., Kobayashi, M.
  • Journal Title: J. Biol. Chem. 279 Pages: 74619
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The Interaction of Covalently Bound Heme with the Cytochrome c Maturation Protein CcmE (2004)
  • Author(s): Uchida, T.*, Stevens, J.M.*, Daltrop, O., Harvat, E.M., Hong, L., Ferguson, S.J., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 51981
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Role of Tyr-288 at the Dioxygen Reduction Site of Cytochrome bo Studied by Stable Isotope Labeling and Resonance Raman Spectroscopy (2004)
  • Author(s): Uchida, T., Mogi, T., Nakamura, H., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 279 Pages: 53613
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Core Structure of Amyloid Fibril Proposed from IR-Microscope Linear Dichroism (2004)
  • Author(s): Hiramatsu, H., Goto, Y., Naiki, H., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 126 Pages: 3008
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Oxygen Sensing Mechanism of HemAT from Bacillus subtilis : A Resonance Raman Spectroscopic Study (2004)
  • Author(s): Ohta, T., Yoshimura, H., Yoshioka, S., Aono, S., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 126 Pages: 15000
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Dioxygen Reactivity of Copper(I) Complexes with Retradentate Tripodal Ligands Having Apliphatic Nitrogen Donors : Synthesis, Structures, and Properties of Peroxo and Superoxo Complexes (2004)
  • Author(s): Komiyama, K., Furutachi, H., Nagatomo, S., Hashimoto, A., Hayashi, H., Fujinami, S., Suzuki, M., Kitagawa, T.
  • Journal Title: Bull. Chem. Soc. Jpn 77 Pages: 59
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Heme Structures of Five Variants of Hemoglobin M Probed by Resonance Raman Spectroscopy (2004)
  • Author(s): Jin, Y., Nagai, M., Nagai, Y., Nagatomo, S., Kitagawa, T.
  • Journal Title: Biochemistry 43 Pages: 8517
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] SOUL in Mouse Eyes is a Novel Hexameric Heme-Binding Protein with Characteristic Optical Absorption, Resonance Raman Spectral and Heme Binding Properties (2004)
  • Author(s): Sato, E., Sagami, I., Uchida, T., Sato, A., Kitagawa, T., Igarashi, J., Shimizu, T.
  • Journal Title: Biochemstry 43 Pages: 14189
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Vibronic Coupling between Soret and Higher Energy Excited States in Iron(II) Porphyrins : Raman Excitation Profiles of A_<2g> Modes in the Soret Region (2004)
  • Author(s): Egawa, T., Suzuki, N., Dokoh, T., Higuchi, T., Shimada, H., Kitagawa, T., Ishimura, Y.
  • Journal Title: J. Phys. Chem. A 108 Pages: 568
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Detection of a Photostable Five-Coordinate Heme α_3-Fe-CO Species and Functional Implications of His384α10 in CO-Bound bα_3-Cytochrome c Oxidase from Thermus thermophilus (2004)
  • Author(s): Ohta, T., Pinakoulaki, E., Soulmane, T., Kitagawa, T., Varotsis, C.
  • Journal Title: J. Phys. Chem. B 108 Pages: 5389
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Model Complexes of the Active Site of Galactose Oxidase. Effects of the Metal Ion Binding Sites (2004)
  • Author(s): Taki, M., Hattori, H., Osako, T., Nagatomo, S., Shiro, M., Kitagawa, T., Itoh, S.
  • Journal Title: Inorg. Chim. Acta 357 Pages: 3369
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Heme Environment in Aldoxime Dehydratase Involved in Carbon-Nitrogen Triple Bond Synthesis (2004)
  • Author(s): Oinuma, K., Ohta, T., Konishi, K., Hashimoto, Y., Higashibata, H., Kitagawa, T., Kobayashi, M.
  • Journal Title: FEBS Lett. 568 Pages: 44
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Steric and Hydrogen-Bonding Effects on the Stability of Copper Complexes with Small Molecules (2004)
  • Author(s): 36.Wada, A., Honda, Y., Yamaguchi, S., Nagatomo, S., Kitagawa, T., Jitsukawa, K., Masuda, H.
  • Journal Title: Inorg. Chem. 43 Pages: 5725
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Thermal Stability of Mononuclear Hydroperoxocopper(II) Species. Effects of Hydrogen Bonding and Hydrophobic Field (2004)
  • Author(s): Yamaguchi, S., Wada, A., Nagatomo, S., Kitagawa, T., Jitsukawa, K., Masuda, H.
  • Journal Title: Chem. Lett. 33 Pages: 1556
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman and Ligand-Binding Analysis of the Oxygen-Sensing Signal Transducer Protein HemAT from Bacillus subtilis (2004)
  • Author(s): Aono, S., Nakajima, H., Ohta, T., Kitagawa, T.
  • Journal Title: Methods Enzymol. 381 Pages: 618
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Correlation between Structural Fluctuation and Reaction in Proteins : An Experimental Approach (2004)
  • Author(s): Mizutani, M.
  • Journal Title: Seibutsubutsuri 44 Pages: 222
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "UV/Vis Absorption, Infrared and Raman Spectroscopy" Tanpakushitsu Kakusan Koso (2004)
  • Author(s): Uchida, T., Kitagawa, T.
  • Journal Title: Kyoritsu Shuppan Pages: 1693
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman Studies on Xanthine Oxiase : Observation of the Mo^<VI>-Liizand Vibration (2003)
  • Author(s): Maiti, N. C.
  • Journal Title: J. Biol. Inorg. Chem. 8 Pages: 327-333
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] C-H Activation by Cu(III)_2-O_2 Intermediate with Secondary Amino Ligand (2003)
  • Author(s): Arii, H.
  • Journal Title: Chem. Lett. 32 Pages: 156-157
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] FTIR Detection of Protonation/Deprotonation of Key Carboxyl Side Chains Caused by Redox Change of the Cu_A-Heme α Moiety and Ligand Dissociation from the Heme a_3-Cu_B Center of Bovine Heart Cvtochrome c Oxidase (2003)
  • Author(s): Okuno, D.
  • Journal Title: J. Am. Chem. Soc. 125 Pages: 7209-7218
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Copper Hydroperoxo Species Activated by Hydrogen-Bonding Interaction with Its Distal Oxygen (2003)
  • Author(s): Yamaguchi, S.
  • Journal Title: Inorg. Chem. 42 Pages: 6968-6970
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Ligand Effect on Reversible Conversion between Copper(I) and Bis(μ-oxo)dicopper(III) Complex with a Sterically Hindered Tetradentate Tripodal Ligand and Monooxygenase Activity of Bis(μ-oxo)dicopper(III) Complex (2003)
  • Author(s): Mizuno, M.
  • Journal Title: Inorg. Chem. 42 Pages: 8534-8544
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Construction of a Square-Planar Hydroperoxo-Copper(II) Complex Inducing a Higher Catalytic Reactivity (2003)
  • Author(s): Fujii, T.
  • Journal Title: Chem. Commun. Pages: 2700-2701
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Thermal Stability and Absorption Spectroscpic Behavior of (μ-Peroxo)dicopper Complexes Regulated with Intramolecular Hydrogen Bonding Interactions (2003)
  • Author(s): Yamaguchi, S.
  • Journal Title: Eur. J. Inorg. Chem. Pages: 4378-4386
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] CO Binding Study of Mouse Heme-Regulated eIF-2α Kinase : Kinetics and Resonance Raman Spectra (2003)
  • Author(s): Igarashi, J.
  • Journal Title: Biochim. Biophys. Acta 1650 Pages: 99-104
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Characterization of the P Intermediate in the Reaction of Bovine Cytochrome c Oxidase (2003)
  • Author(s): Ogura, T.
  • Journal Title: Biochim. Biophys. Acta 1655 Pages: 290-297
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman Studies on Xanthine Oxiase : Observation of the Mo^<VI>-Ligand Vibration (2003)
  • Author(s): Maiti, N.C., Tomita, T., Kitagawa, T., Okamoto, K., Nishino, T.
  • Journal Title: J. Biol. Inorg. Chem. 8 Pages: 327
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] C-H Activation by Cu(III)2-O2 Intermediate with Secondary Amino Ligand (2003)
  • Author(s): Arii, H., Saito, Y., Nagatomo, S., Kitagawa, T., Funahashi, Y., Jitsukawa, K., Masuda, H.
  • Journal Title: Chem. Lett. 32 Pages: 156
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] FTIR Detection of Protonation/Deprotonation of Key Carboxyl Side Chains Caused by Redox Change of the CuA-Heme α Moiety and Ligand Dissociation from the Heme α_3-Cu_B Center of Bovine Heart Cytochrome c Oxidase (2003)
  • Author(s): Okuno, D., Iwase, T., Shinzawa-Itoh, K., Yoshikawa, S., Kitagawa, T.
  • Journal Title: J. Am. Chem. Soc. 125 Pages: 7209
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Copper Hydroperoxo Species Activated by Hydrogen-Bonding Interaction with Its Distal Oxygen (2003)
  • Author(s): Yamaguchi, S., Nagatomo, S., Kitagawa, T., Funahashi, Y., Ozawa, T., Jitsukawa, K., Masuda, H.
  • Journal Title: Inorg. Chem. 42 Pages: 6968
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Ligand Effect on Reversible Conversion between Copper(I) and Bis(μ-oxo)dicopper(III) Complex with a Sterically Hindered Tetradentate Tripodal Ligand and Monooxygenase Activity of Bis(μ-oxo)dicopper(III) Complex (2003)
  • Author(s): Mizuno, M., Hayashi, H., Fujinami, S., Furutachi, H., Nagatomo, S., Otake, S., Uozumi, K., Suzuki, M., Kitagawa, T.
  • Journal Title: Inorg. Chem. 42 Pages: 8534
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Construction of a Square-Planar Hydroperoxo-Copper(II) Complex Inducing a Higher Catalytic Reactivity (2003)
  • Author(s): Fujii, T., Naito, A., Yamaguchi, S., Wada, A., Funahashi, Y., Jitsukawa, K., Nagatomo, S., Kitagawa, T., Masuda, H.
  • Journal Title: Chem. Commun. Pages: 2700
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Thermal Stability and Absorption Spectroscpic Behavior of (μ-Peroxo)dicopper Complexes Regulated with Intramolecular Hydrogen Bonding Interactions (2003)
  • Author(s): Yamaguchi, S., Wada, A., Funahashi, Y., Nagatomo, S., Kitagawa, T., Jitsukawa, K., Masuda, H.
  • Journal Title: Eur. J. Inorg. Chem. Pages: 4378
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] CO Binding Study of Mouse Heme-Regulated eIF-2α Kinase : Kinetics and Resonance Raman Spectra (2003)
  • Author(s): Igarashi, J., Sato, A., Kitagawa, T., Sagami, I., Shimizu, T.
  • Journal Title: Biochim. Biophys. Acta 1650 Pages: 99
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Physical Chemistry for the Chemical and Biological Sciences" (Raymond Chang) (2003)
  • Author(s): Iwasawa, Y., Kitagawa, T., Hamaguchi, H.
  • Journal Title: Tokyo Kagaku Dozin Co., Ltd.
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Observation of an Isotope Sensitive Low Frequency Raman Band Specific to Metmyoglobin (2002)
  • Author(s): Hirota, S
  • Journal Title: J. Biol. Inorg. Chem. 7 Pages: 217-221
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] UV Resonance Raman Characterization of Model Compounds of Tyr244 of Bovine Cytochrome c Oxidase in Its Neutral, Deprotonated Anion, and Deprotonated Neutral Radical Forms; Effects of Covalent Binding between Tyrosine and Histidine (2002)
  • Author(s): Aki, M.
  • Journal Title: J. Phys. Chem. A 106 Pages: 3436-3444
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Resonance Raman and Ligand Binding Studies of the Oxygen Sensing Signal Transducer Protein HemAT from Bacillus subtilis (2002)
  • Author(s): Aono, S.
  • Journal Title: J. Biol. Chem. 277 Pages: 13528-13538
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Stationary and Time-Resolved Resonance Raman Spectra of His" and Met^<95> Mutants of the Isolated Heme Domain of a Direct Oxygen Sensor from Escherichia coli (2002)
  • Author(s): Sato, A.
  • Journal Title: J. Biol. Chem. 277 Pages: 32650-32658
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Time-Resolved UV Resonance Raman Investigation of Protein Folding Using a Rapid Mixer : Characterization of Kinetic Folding Intermediates of Apomyoglobin (2002)
  • Author(s): Haruta, N.
  • Journal Title: Biochemistry 41 Pages: 6595-6604
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Differences in Changes of the αl-β2 Subunit Contacts between Ligand Binding to the α and β Subunits of Hemoglobin A : UV Resonance Raman Analysis Using Ni-Fe Hybrid Hemoglobin (2002)
  • Author(s): Nagatomo, S.
  • Journal Title: Biochemistry 41 Pages: 10010-10020
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Vibrational Energy Relaxation of Metalloporphyrins in a Condensed Phase Probed by Time-Resolved Resonance Raman Spectroscopy (2002)
  • Author(s): Mizutani, Y.
  • Journal Title: Bull. Chem. Soc. Jpn. 75 Pages: 623-639
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Time-resolved Resonance Raman Study on Ultrafast Structural Relaxation and Vibrational Cooling of Photodissociated Carbonmonoxy Myoglobin (2002)
  • Author(s): Mizutani, Y.
  • Journal Title: Bull. Chem. Soc. Jpn. 75 Pages: 965-971
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Time-Resolved Resonance Raman Study on Ultrafast Structural Relaxation and Vibrational Cooling of Photodissociated Carbonmonoxy Myoglobin (2002)
  • Author(s): Kitagawa, T.
  • Journal Title: Biopolymers (Biospectroscopy) 67 Pages: 207-213
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] UV Resonance Raman and NMR Spectroscopic Studies on the pH Dependent Metal Ion Release from Pseudoazurin (2002)
  • Author(s): Sato, K.
  • Journal Title: Inorg. Chim. Acta 339 Pages: 383-392
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Changes in the Abnormal α-Subunit upon CO-Binding to the Normal β-subunit of Hb M Boston : Resonance Raman, EPR, and CD Study (2002)
  • Author(s): Nagatomo, S.
  • Journal Title: Biophys. Chem. 98 Pages: 217-232
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Fine Tuning of Copper(I)-Dioxygen Reactivity with 2-(2-Pyridyl)ethylamine Bidentate Ligands (2002)
  • Author(s): Taki, M.
  • Journal Title: J. Am. Chem. Soc. 124 Pages: 6367-6377
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Reactivity of Hydroperoxide Bound to a Mononuclear Non-Heme Iron Site (2002)
  • Author(s): Wada, A.
  • Journal Title: Inorg. Chem. 41 Pages: 616-618
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Modulation of the Copper-Dioxygen Reactivity by Stereochemical Effect of Tetradentate Tripodal Ligands (2002)
  • Author(s): Hayashi, H.
  • Journal Title: Chem. Lett. 31 Pages: 416-417
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] A New Mononuclear Iron(III) Complex Containing a Peroxocarbonate Ligand (2002)
  • Author(s): Hashimoto, K.
  • Journal Title: Angew. Chem. Intnl. Ed. 41 Pages: 1202-1205
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Coordination Geometry of Cu-Porphyrin in Cu(II)-Fe(II) Hybrid Hemoglobins Studied by Q-Band EPR and Resonance Raman Spectroscopies (2002)
  • Author(s): Venkatesh, B.
  • Journal Title: J. Inorg. Biochem. 88 Pages: 310-315
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Structural and Spectroscopic Features of a cis (Hydroxo)-Fe-^<III>-(Carboxylato) Configuration as an Active Site Model for Lipoxygenases (2002)
  • Author(s): Ogo, S.
  • Journal Title: Inorg. Chem. 41 Pages: 5513-5520
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Low-Temperature Stopped-Flow Studies on the Reactions of Copper(II) Complexes and H_2O_2 : The First Detection of a Mononuclear Copper(II)-Peroxo Intermediate (2002)
  • Author(s): Osako, T.
  • Journal Title: Angew. Chem. Int. Ed. 41 Pages: 4325-4328
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Observation of an Isotope Sensitive Low Frequency Raman Band Specific to Metmyoglobin (2002)
  • Author(s): Hirota, S., Mizoguchi, Y., Yamauchi, O., Kitagawa, T.
  • Journal Title: J. Biol. Inorg. Chem. 7 Pages: 217
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] UV Resonance Raman Characterization of Model Compounds of Tyr244 of Bovine Cytochrome c Oxidase in Its Neutral, Deprotonated Anion, and Deprotonated Neutral Radical Forms; Effects of Covalent Binding between Tyrosine and Histidine (2002)
  • Author(s): Aki, M., Ogura, T., Naruta, Y., Le, T.H., Sato, T., Kitagawa, T.
  • Journal Title: J. Phys. Chem. A 106 Pages: 3436
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Resonance Raman and Ligand Binding Studies of the Oxygen Sensing Signal Transducer Protein HemAT from Bacillus subtilis (2002)
  • Author(s): Aono, S., Kato, T., Matsuki, M., Nakajima, H., Ohta, T., Uchida, T., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 277 Pages: 13528
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Stationary and Time-Resolved Resonance Raman Spectra of His^<77> and Met^<95> Mutants of the Isolated Heme Domain of a Direct Oxygen Sensor from Escherichia coli (2002)
  • Author(s): Sato, A., Sasakura, Y., Sugiyama, S., Sagami, I., Shimizu, T., Mizutani, Y., Kitagawa, T.
  • Journal Title: J. Biol. Chem. 277 Pages: 32650
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Time-Resolved UV Resonance Raman Investigation of Protein Folding Using a Rapid Mixer : Characterization of Kinetic Folding Intermediates of Apomyoglobin (2002)
  • Author(s): Haruta, N., Kitagawa, T.
  • Journal Title: Biochemistry 41 Pages: 6595
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Differences in Changes of the αl-β2 Subunit Contacts between Ligand Binding to the α and β Subunits of Hemoglobin A : UV Resonance Raman Analysis Using Ni-Fe Hybrid Hemoglobin (2002)
  • Author(s): Nagatomo, S., Nagai, M., Shibayama, N., Kitagawa, T.
  • Journal Title: Biochemistry 41 Pages: 10010
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Vibrational Energy Relaxation of Metalloporphyrins in a Condensed Phase Probed by Time-Resolved Resonance Raman Spectroscopy (2002)
  • Author(s): Mizutani, Y., Kitagawa, T.
  • Journal Title: Bull. Chem. Soc. Jpn 75 Pages: 623
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Mode Dependence of Vibrational Energy Redistribution in Nickel Tetraphenylporphyrin Probed by Picosecond Time-Resolved Resonance Raman Spectroscopy : Slow IVR to Phenyl Peripherals (2002)
  • Author(s): Mizutani, Y., Kitagawa, T.
  • Journal Title: Bull. Chem. Soc. Jpn 75 Pages: 965
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Time-Resolved Resonance Raman Study on Ultrafast Structural Relaxation and Vibrational Cooling of Photodissociated Carbonmonoxy Myoglobin (2002)
  • Author(s): Kitagawa, T., Haruta, N., Mizutani, Y.
  • Journal Title: Biopolymers (Biospectroscopy) 67 Pages: 207
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] UV Resonance Raman and NMR Spectroscopic Studies on the pH Dependent Metal Ion Release from Pseudoazurin (2002)
  • Author(s): Sato, K., Nagatomo, S., Dennison, C., Niizeki, T., Kitagawa, T., Kohzuma, T.
  • Journal Title: Inorg. Chim. Acta 339 Pages: 383
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Changes in the Abnormal α-Subunit upon CO-Binding to the Normal β-subunit of Hb M Boston : Resonance Raman, EPR, and CD Study (2002)
  • Author(s): Nagatomo, S., Jin, Y., Nagai, M., Hori, H., Kitagawa, T.
  • Journal Title: Biophys. Chem. 98 Pages: 217
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Fine Tuning of Copper(I)-Dioxygen Reactivity with 2-(2-Pyridyl)ethylamine Bidentate Ligands (2002)
  • Author(s): Taki, M., Teramae, S., Nagatomo, S., Tachi, Y., Kitagawa, T., Itoh, S., Fukuzumi, S.
  • Journal Title: J. Am. Chem. Soc. 124 Pages: 6367
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Reactivity of Hydroperoxide Bound to a Mononuclear Non-Heme Iron Site (2002)
  • Author(s): Wada, A., Ogo, S., Nagatomo, S., Kitagawa, T., Watanabe, Y., Jitsukawa, K., Masuda, H.
  • Journal Title: Inorg. Chem. 41 Pages: 616
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Modulation of the Copper-Dioxygen Reactivity by Stereochemical Effect of Tetradentate Tripodal Ligands (2002)
  • Author(s): Hayashi, H., Uozumi, K., Fujinami, S., Nagatomo, S., Shiren, K., Furutachi, H., Suzuki, M., Uehara, A., Kitagawa, T.
  • Journal Title: Chem. Lett. 31 Pages: 416
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A New Mononuclear Iron(III) Complex Containing a Peroxocarbonate Ligand (2002)
  • Author(s): Hashimoto, K., Nagatomo, S., Fujinami, S., Furutachi, H., Ogo, S., Suzuki, S., Uehara, A., Maeda, Y., Watanabe, Y., Kitagawa, T.
  • Journal Title: Angew. Chem. Intnl. Ed. 41 Pages: 1202
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Coordination Geometry of Cu-Porphyrin in Cu(II)-Fe(II) Hybrid Hemoglobins Studied by Q-Band EPR and Resonance Raman Spectroscopies (2002)
  • Author(s): Venkatesh, B., Hori, H., Miyazaki, G., Nagatomo, S., Kitagawa, T., Morimoto, H.
  • Journal Title: J. Inorg. Biochem. 88 Pages: 310
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Structural and Spectroscopic Features of a cis (Hydroxo)-Fe-^<III>-(Carboxylato) Configuration as an Active Site Model for Lipoxygenases (2002)
  • Author(s): Ogo, S., Yamahara, R., Roach, M., Suenobu, T., Aki, M., Ogura, T., Kitagawa, T., Masuda, H., Fukuzumi, S., Watanabe, Y.
  • Journal Title: Inorg. Chem. 41 Pages: 5513
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Low-Temperature Stopped-Flow Studies on the Reactions of Copper(II) Complexes and H_2O_2 : The First Detection of a Mononuclear Copper(II)-Peroxo Intermediate (2002)
  • Author(s): Osako, T., Nagatomo, S., Tachi, Y., Kitagawa, T., Itoh, S.
  • Journal Title: Angew. Chem. Int. Ed. 41 Pages: 4325
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Resonance Raman Spectroscopy" J. Porphyrins Phthalocyanines (2002)
  • Author(s): Kitagawa, T.
  • Journal Title: Society of Porphyrine and Phtalocyanines Pages: 301
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] "Raman Spectroscopy of Proteins" in 'Handbook of Vibrational Spectroscopy' (2002)
  • Author(s): Kitagawa, T., Hirota, S.
  • Journal Title: John Wiley ＆ Sons, Ltd. Chichester
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] ガスセンサーヘム蛋白質の情報検出及び伝達の構造化学(豊田研究報告) (2007)
  • Author(s): 北川 禎三
  • Total Pages: 81-88 (8)
  • Publisher: 豊田理化学研究所
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 生命科学系のための物理化学 (2006)
  • Author(s): 岩澤 康裕
  • Total Pages: (448)
  • Publisher: 東京化学同人
  • Description: 「研究成果報告書概要(和文)」より
• [Book] ラマン分光(光科学研究の最前線) (2005)
  • Author(s): 内田 毅
  • Total Pages: 96-97 (2)
  • Publisher: 強光子場科学研究懇談会
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 可視・紫外・赤外・ラマン分光法 『蛋白質 核酸 酵素』増刊号 バイオ高性能機器・新技術利用マニュアル (2004)
  • Author(s): 内田 毅
  • Total Pages: 1693-1699 (7)
  • Publisher: 共立出版
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 「時間分解振動分光法で観たタンパク質の動き」ナノバイオテクノロジーの最前線 (2003)
  • Author(s): 水谷 泰久
  • Total Pages: 425-437 (13)
  • Publisher: シーエムシー出版
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 「ヘモグロビンの機能と高次構造変化-ゲルマトリックスを用いて構造変化をスローモーションで観る」化学 (2003)
  • Author(s): 水谷 泰久
  • Total Pages: 54-55 (2)
  • Publisher: 化学同人
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 化学・生命科学系のための物理化学 (2003)
  • Author(s): 岩澤 康裕
  • Total Pages: (688)
  • Publisher: 東京化学同人
  • Description: 「研究成果報告書概要(和文)」より
• [Book] J. Porphyrins Phthalocyanines, Resonance Raman Spectroscopy (2002)
  • Author(s): Kitagawa, T.
  • Total Pages: 301-302 (2)
  • Publisher: Society of Porphyrine and Phthalocyanines
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Handbook of Vibrational Spectroscopy, Raman spectroscopy of Proteins (2002)
  • Author(s): Kitagawa, T
  • Total Pages: (21)
  • Publisher: John Wiley ＆ Sons, Ltd. Chichester
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 物理化学から生体分子科学へ(未来材料) (2002)
  • Author(s): 北川 禎三
  • Total Pages: 75-78 (4)
  • Publisher: (株)エヌ・ティー・エス
  • Description: 「研究成果報告書概要(和文)」より