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2004 Fiscal Year Final Research Report Summary

Development of Real-Time MR Image guided Surgery

Research Project

Project/Area Number 14370352
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionShiga University of Medical Science

Principal Investigator

KURUMI Yoshimasa  Shiga University of Medical Science, Assistant Professor, 医学部, 講師 (70205219)

Co-Investigator(Kenkyū-buntansha) TANI Tohru  Shiga University of Medical Science, Professor, 医学部, 教授 (20179823)
MORIKAWA Shigehiro  MR Medical Research Center, Associate Professor, MRI医学総合研究センター, 助教授 (60220042)
ENDO Yoshihiro  Shiga University of Medical Science, Instructor, 医学部, 助手 (40263040)
NAKA Shigeyuki  Shiga University of Medical Science, Instructor, 医学部, 助手 (10359771)
HANASAWA Kazuyoshi  Shiga University of Medical Science, Associate Professor, 医学部, 助教授 (80146406)
Project Period (FY) 2002 – 2004
KeywordsNavigation Surgery / Real Time MR Image / Microwave Coagulation Therapy / Open MR / Microwave Surgery / MR Thermal Image / Vertical Open MR / 4 Dimensional Image
Research Abstract

Results outline of the research :
We have developed Real-time MR image guided surgery system and clarified a new effect of microwave.
1.Real-time MR image guided surgery : Real-time MR image guided surgery is carried out on a 0.5T vertically oriented open MR scanner (SIGNA SP/i). We also developed the original MRI navigation system which consists of a personal computer and integrated into the open MR scanner. The virtual organ image is reconstructed from a previously acquired MR or CT image. The composite image which contains the virtual slice image, real time MR image, temperature monitoring image, virtual 3D image and endoscopic image is shown on the LCD monitor in the bore of open MR scanner.
2.Real-time MR Temperature Monitoring : This technique is useful for the evaluation of microwave electrodes and for the optimization of output power and duration in microwave ablation. Real-time MR temperature images are calculated by the proton resonance frequency method and utilized in MRI navigation system.
3.New Effect of Microwave : Microwave fixation can be considered a type of coagulative necrosis without enzyme digestion. Disruption of erythrocytes on HE staining is an interesting and important diagnostic clue in distinguishing non-viable fixed tissues from viable tissues following microwave coagulation therapy.

  • Research Products

    (38 results)

All 2005 2004 2003 2002

All Journal Article (37 results) Book (1 results)

  • [Journal Article] Open-Configuration MR-Guided Microwave Thermocoagulation Therapy for Metastatic Liver Tumors from Breast Cancer2005

    • Author(s)
      Hajime ABE
    • Journal Title

      Breast Cancer 12(1)

      Pages: 26-31

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Distribution of erythrocytes distinguishes fixed cells / tissues from viable cells / tissues following microwave coagulation therapy2005

    • Author(s)
      Tsuyoshi YAMAGAUCHI
    • Journal Title

      Digestive Diseases and Science (In press)

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Open-Configuration MR-Guided Microwave Thermocoagulation Therapy for Metastatic Liver Tumors from Breast Cancer2005

    • Author(s)
      Hajime ABE, Yoshimasa KURUMI, Shigeyuki NAKA, Hisanori SHIOMI, Tomoko UMEDA, Hiroyuki Naito, Yoshihiro ENDO, Kazuyoshi HANASAWA, Shigehiro MORIKAWA, Tohru TANI
    • Journal Title

      Breast Cancer 12(1)

      Pages: 26-31

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Distribution of erythrocytes distinguishes fixed cells/tissues from viable cells/tissues following microwave coagulation therapy2005

    • Author(s)
      Tsuyoshi YAMAGAUCHI, Ken-ichi MUKAISHO, Hiroshi YAMAMOTO, Hisanori SHIOMI, Yoshimasa KURUMI, Hiroyuki SUGIHARA, Tohru
    • Journal Title

      Digestive Diseases and Science (In press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Robotic surgery in cancer2005

    • Author(s)
      Yoshimasa KURUMI, Shigehiro MORIKAWA, Shigeyuki NAKA, Hisanori SHIOMI, Hisakazu HOSHI, Tohru TANI
    • Journal Title

      New Perspective in Cancer Research and Therapy (In press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Feasibility of respiratory triggering for MR-guided microwave ablation of liver tumors under general anesthesia2004

    • Author(s)
      Shigehiro MORIKAWA
    • Journal Title

      Cardiovasc Intervent Radiol 27

      Pages: 370-373

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 肝癌に対するMR Navigationによるマイクロ波凝固療法2004

    • Author(s)
      来見良誠
    • Journal Title

      外科治療 90

      Pages: 89-90

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MRガイド下マルチチャンネルマイクロ波凝固のためのマルチスライスMR温度モニタリング2004

    • Author(s)
      森川茂廣
    • Journal Title

      J Microwave Surg 22

      Pages: 57-61

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MR空間におけるMicrowave surgeryの各種疾患への応用-甲状腺腫瘍-2004

    • Author(s)
      来見良誠
    • Journal Title

      J Microwave Surg. 22

      Pages: 37-41

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MR空間におけるMicrowave surgeryの各種疾患への応用-骨盤内腫瘍-2004

    • Author(s)
      遠藤善裕
    • Journal Title

      J Microwave Surg. 22

      Pages: 43-57

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MR空間におけるMicrowave Surgeryの現況と展望2004

    • Author(s)
      来見良誠
    • Journal Title

      J Microwave Surg. 22

      Pages: 31-35

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Open MRを用いた手術ナビゲーション2004

    • Author(s)
      森川茂廣
    • Journal Title

      J.JSCAS 6(2)

      Pages: 79-82

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] マイクロ波による治療の新展開2004

    • Author(s)
      谷 徹
    • Journal Title

      Medical Science Digest 30(9)

      Pages: 23-26

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Feasibility of respiratory triggering for MR-guided microwave ablation of liver tumors under general anesthesia2004

    • Author(s)
      Shigehiro MORIKAWA, Toshiro INUBUSHI, Yoshimasa KURUMI, Shigeyuki NAKA, Koichirou SATO, Kouichi DEMURA, Tohru TANI, Hasnine A Haque
    • Journal Title

      Academic Radiology 27

      Pages: 370-373

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 進行・再発大腸癌に対するinterventional MR navigation surgery2003

    • Author(s)
      遠藤善裕
    • Journal Title

      外科 65(10)

      Pages: 1147-1152

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] New assistive devices for MR-guided microwave thermocoagulation of liver tumors2003

    • Author(s)
      Shigehiro MORIKWAWA
    • Journal Title

      Acad Radiol 10

      Pages: 180-188

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 局所再発直腸癌に対するMRI navigation surgery2003

    • Author(s)
      遠藤善裕
    • Journal Title

      手術 57(12)

      Pages: 1491-1497

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Advanced computer assistance for magnetic resonance-guided microwave thermocoagulation of liver tumors2003

    • Author(s)
      Shigehiro MORIKAWA
    • Journal Title

      Acad Radiol 10

      Pages: 1442-1449

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 肝腫瘍マイクロ波凝固治療におけるMR温度モニタリングの改良2003

    • Author(s)
      森川茂廣
    • Journal Title

      J Microwave Surg 21

      Pages: 43-47

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] New assistive devices for MR-guided microwave thermocoagulation of liver tumors2003

    • Author(s)
      Shigehiro MORIKWAWA, Toshiro INUBUSHI, Yoshimasa KURUMI, Shigeyuki NAKA, Koichiro SATO, Tohru TANI, Hasnine A Haque, Junichi TOKUDA, Nobuhiko HATA, Tani T, Haque HA, Tokuda J, Hata N.
    • Journal Title

      Academic Radiology 10

      Pages: 180-188

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Advanced computer assistance for magnetic resonance-guided microwave thermocoagulation of liver tumors2003

    • Author(s)
      Shigehiro MORIKAWA, Toshiro INUBUSHI, Yoshimasa KURUMI, Shigeyuki NAKA, Koichiro SATO, Kouichi DEMURA, Tohru TANI, Hasnine A Haque, Junichi TOKUDA, Nobuhiko HATA
    • Journal Title

      Academic Radiology 10

      Pages: 1442-1449

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Effects o f Microwave Irradiation on Rat Hepatic Tissue Evaluated by Enzyme Histochemistry for Acid Phosphatase2002

    • Author(s)
      Ken-ichi MUKAISHO
    • Journal Title

      Digestive Diseases and Science 47

      Pages: 376-379

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 腹部病変に対するオープンMRIを用いたMicrowave Surgery2002

    • Author(s)
      谷 徹
    • Journal Title

      Radiology Frontier 5(1)

      Pages: 31-36

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MR監視下肝腫瘍マイクロ波凝固療法2002

    • Author(s)
      来見良誠
    • Journal Title

      臨床消化器内科 17(4)

      Pages: 523-528

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MRIガイド下における肝腫瘍治療2002

    • Author(s)
      仲 成幸
    • Journal Title

      手術 56(8)

      Pages: 1053-1059

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 腹部外科とナビゲーションサージェリー2002

    • Author(s)
      谷 徹
    • Journal Title

      手術 56(10)

      Pages: 1451-1460

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 垂直型オープンMRIを用いた癌治療2002

    • Author(s)
      谷 徹
    • Journal Title

      血液・腫瘍科 44(3)

      Pages: 195-202

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Enzyme Histochemistry is Useful to Assess Viability of Tumor Tissue after Microwave Coagulation Therapy2002

    • Author(s)
      Ken-ichi MUKAISHO
    • Journal Title

      Digestive Diseases and Science 47(11)

      Pages: 2441-2445

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors : Initial Clinical Experiences Using a 0.5 T Open MR System2002

    • Author(s)
      Shigehiro MORIKAWA
    • Journal Title

      Journal of Magnetic Resonance Imaging 16

      Pages: 576-583

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Technical Developments for MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors2002

    • Author(s)
      Shigehiro MORIKAWA
    • Journal Title

      Lecture Notes in Computer Science 2

      Pages: 52-59

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] マイクロ波出力と針状電極の形状による加温領域への影響-MR温度画像を用いた連続的モニタリング-2002

    • Author(s)
      森川茂廣
    • Journal Title

      J.Microwave Surg. 20

      Pages: 27-33

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] リアルタイムMR画像ガイド下手術へのカスタマイズしたナビゲーションソフトウェアの統合2002

    • Author(s)
      森川茂廣
    • Journal Title

      J.JSCAS 4(1)

      Pages: 27-33

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] リアルタイムMR画像ガイドにおけるオフセット型穿刺補助器具の開発2002

    • Author(s)
      森川茂廣
    • Journal Title

      J.JSCAS 4(4)

      Pages: 345-350

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Effects of Microwave Irradiation on Rat Hepatic Tissue Evaluated by Enzyme Histochemistry for Acid Phosphata2002

    • Author(s)
      Ken-ichi MUKAISHO, Hiroyuki SUGIHARA, Tohru TANI, Yoshimasa KURUMI, Sumihiro KAMITANI, Tomoki TOKUGAWA, Takanori HATTORI
    • Journal Title

      Digestive Diseases and Science 47

      Pages: 376-379

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Enzyme Histochemistry is Useful to Assess Viability of Tumor Tissue after Microwave Coagulation Therapy2002

    • Author(s)
      Ken-ichi MUKAISHO, Yoshimasa KURUMI, Hiroyuki SUGIHARA, Shigeyuki.NAKA, Yasuhiro TSUBOSA, Suzuko MORITANI, Yoshihiro ENDO, Kazuyoshi HANASAWA, Shigehiro MORIKAWA, Toshiro INUBUSHI, Takanori HATTORI, Tohru TANI
    • Journal Title

      Digestive Diseases and Science 47(11)

      Pages: 2441-2445

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors : Initial Clinical Experiences Using a 0.5 T Open MR System2002

    • Author(s)
      Shigehiro MORIKAWA, Toshiro INUBUSHI, Yoshimasa KURUMI, Shigeyuki NAKA, Koichiro SATO, Tohru TANI, Ikuo YAMAMOTO, Masaki FUJIMURA
    • Journal Title

      Journal of Magnetic Resonance Imaging 16

      Pages: 576-583

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Technical Developments for MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors2002

    • Author(s)
      Shigehiro MORIKAWA, Toshiro INUBUSHI, Yoshimasa KURUMI, Shigeyuki NAKA, Koichiro SATO, Tohru TANI, Nobuhiko HATA, Viswanathan Seshan, Hasnine A Haque
    • Journal Title

      Lecture Notes in Computer Science 2

      Pages: 52-59

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] New Perspective in Cancer Research and Therapy2005

    • Author(s)
      Yoshimasa KURUMI
    • Publisher
      (In Press)
    • Description
      「研究成果報告書概要(和文)」より

URL: 

Published: 2006-07-11  

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