2005 Fiscal Year Final Research Report Summary
Development of an axial flow blood pump using a hydrodynamic pressure bearing
| Project/Area Number |
14380386
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
MITAMURA Yoshinori Hokkaido University, Graduate School of Information Science and Technology, Professor, 大学院・情報科学研究科, 教授 (70002110)
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| Co-Investigator(Kenkyū-buntansha) |
MURABAYASHI Shun Hokkaido University, Graduate School of Information Science and Technology, Associate Professor, 大学院・情報科学研究科, 助教授 (30200306)
NISHIMURA Ikuya Hokkaido University, Graduate School of Information Science and Technology, Assistant Professor, 大学院・情報科学研究科, 助手 (00228214)
OKAMOTO Eiji Hokkaido Tokai University, School of Engineering, Associate Professor, 工学部, 助教授 (30240633)
YOZU Rhohei Keio University, Medical School, Professor, 医学部, 教授 (30129738)
YAMBE Tomoyuki Tohoku University, Institute of Development Aging and Cancer, Professor, 加齢医学研究所, 教授 (70241578)
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| Project Period (FY) |
2002 – 2005
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| Keywords | Artificial heart / Blood pump / Hydrodynamic pressure bearing / Magnetic fluid seal / Computational fluid dynamics |
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| Research Abstract |
An axial flow blood pump was developed using a hydrodynamic pressure bearing, a magnetic fluid seal and a brushless direct current motor. This enabled contact-free rotation of the impeller without material wear. The motor rotor is directly connected to the impeller by a motor shaft. A hydrodynamic pressure bearing is installed on the motor shaft. The motor and the hydrodynamic bearing are housed in a cylindrical casing and are waterproofed by a magnetic fluid seal. The magnetic fluid seal was developed for use in an axial-flow blood pump. Sealing pressures at motor speeds of up to 10,000 rpm were measured with the seal immersed in water. The sealing pressure was above 400 mm Hg. The seal, installed in the pump, remained perfect for 60 days at a flow of 4 L/min against a pressure of 150 mmHg. Results of measurement of cell growth activity indicated that the magnetic fluid has no negative cytological effects. The developed blood pump could eject a flow of 5 L/min at a pressure difference of 100 mmHg with an allowable hemolysis level (N.I.H.<0.02).
The axial flow blood pump was implanted in goats between the left ventricle and the descending aorta. The goat survived for two days and a total left ventricular bypass was obtained with the pump.
A control system of the axial flow blood pump was developed. A prediction method of the pump flow based on power consumption of the motor and motor speed was proposed. Pump flow was predicted with an error of less than 10%. Backflow through the pump and obstruction of the inflow cannula were automatically detected based on the wave distortion rate of the motor current. The distortion rate was computed using the Walsh functions.
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[Journal Article] A mechanically non-contact axial flow blood pump2006
Author(s)
Mitamura, Y., Kido, K., Yano, T., Sakota, D., Yozu, R., Okamoto, E., Murabayashi, S., Nishimura, I.
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Journal Title
Biocybernetics and Biomedical Engineering 26(1)
Pages: 49-54
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Current status of the intra-cardiac axial flow pump2005
Author(s)
Mitamura, Y., Yano, T., Kido, K., Sakota, D., Takahashi, N., Mori, Y., Murabayashi, S., Nishimura, I., Sekine, K.
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Journal Title
Lecture note on the ICB seminar
Pages: 23-26
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Design improvement of the rotary blood pump by computational fluid dynamics analysis (in Japanese)2005
Author(s)
Yano, T., Mitoh, A., Mitamura, Y., Nishimura, I., Murabayashi, S., Yozu, R.
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Journal Title
Transactions of Japanese Society for Medical & Biological Engineering 43(1)
Pages: 85-92
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] A small axial flow blood pump2004
Author(s)
Mitamura, Y.
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Journal Title
Technical Report, Toward industrialization of medical electromagnetic driving systems, The Institute of Electrical Engineers of Japan No.958
Pages: 13-17
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] An Estimation Method of Hemolysis within an Axial Flow Blood Pump by Computational Fluid Dynamics (CFD) Analysis2003
Author(s)
Yano, T., Sekine, K., Mitoh, A., Mitamura, Y., Okamoto, E., Kim, D.-W.: Nishimura, I., Murabayashi, S., Yozu, R.
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Journal Title
Artificial Organs 27(10)
Pages: 920-925
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Development of a Magnetic Fluid Shaft Seal for an Axial-Flow Blood Pump2003
Author(s)
Sekine, K., Mitamura, Y., Murabayashi, S., Nishimura, I., Yozu, Y., Kim, D.-W.
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Journal Title
Artificial Organs 27(10)
Pages: 892-896
Description
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