2004 Fiscal Year Final Research Report Summary
Development of linear motor driven pulsatile ventricular assist device
| Project/Area Number |
14380416
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Denki University |
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Principal Investigator |
FUKUI Yasuhiro Tokyo Denki University, School of Science and Engineering, Professor, 理工学部, 教授 (60112877)
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| Co-Investigator(Kenkyū-buntansha) |
FUNAKUBO Akio Tokyo Denki University, School of Science and Engineering, Assistant Professor, 理工学部, 助教授 (00307670)
MIYAWAKI Fujio Tokyo Denki University, School of Science and Engineering, Professor, 理工学部, 教授 (50174222)
MASUZAWA Toru Ibaraki University, Faculty of Engineering, Professor, 工学部, 教授 (40199691)
SAKUMA Ichiro The University of Tokyo, Graduate School of Frontier Science, Professor, 大学院・新領域創成科学研究科, 教授 (50178597)
FUKUNAGA Kazuyoshi Tokyo Denki University, Frontier Research and Development Center, Research Associate, フロンティア共同研究センター, 助手 (30366405)
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| Project Period (FY) |
2002 – 2004
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| Keywords | Artificial Heart / Ventricular Assist Device / Linear Motor / Linear Oscillatory Actuator / Non-Symmetrical Thrust Characteristics / Magnetic Field Analysis / Movement Converter / Chronic Animal Experiment |
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| Research Abstract |
Heart transplantation is a reliable way to treat patients with severe cardiac failure. The limited number of donor hearts available requires the establishment of alternative treatments for these patients. A left ventricular assist device(VAD) has been used for such patients and has shown reliable results as a bridge to heart transplantation. Electromechanical and electrohydraulic mechanisms have been reported as the driving mechanisms for pulsatile VADs. These require a movement converter, such as a roller screw. This causes problems in that the use of the movement converter prevents the VAD from becoming smaller and reduces the reliability of the VAD.
In this study, a new implantable direct electromagnetic VAD (Linear-VAD) was developed, that uses a linear oscillatory actuator(LOA) without any movement converter. A magnetic field analysis was applied to examine proposal structures and to design LOA. The three proposal structures of LOA are as follows :
(1)New structure of the Inner-Stator/Outer-Mover.
(2)New structure which has the non-symmetrical thrust characteristics.
(3)The structure to improve the starting thrust.
The dimensions of prototype LOA are 60 mm in diameter, 24 mm in thickness, with a mass of 465 g and a volume of 68 mL, Moreover, the prototype Linear-VAD was developed that uses the LOA. The dimensions of the first prototype Linear-VAD are 96 mm in diameter, 50 mm in thickness, with a mass of 0.62 kg and a volume of 280 mL. An in vitro test demonstrated over 10 L/min maximum output and 18 % maximum efficiency. The Linear-VAD was evaluated for pump performance, long-term durability in a chronic animal experiment. The goat implanted with the Linear-VAD survived for 42 days. The Linear-VAD had no troubles relating to the electronic control unit or the electronic drive line. The experiment confirmed the durability of the Linear-VAD for 42 days.
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